25 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PVRL1	Nectin-1. (710 aa)
	NPC1-2	SSD domain-containing protein. (1281 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (925 aa)
	CD68	Macrosialin. (403 aa)
	GLB1-2	Beta-galactosidase. (651 aa)
	GLB1L2	Beta-galactosidase. (635 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
	SAMHD1	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1. (629 aa)
	AXL	Tyrosine-protein kinase receptor UFO isoform B. (557 aa)
	RHOA	Transforming protein RhoA. (255 aa)
	CD40	Tumor necrosis factor receptor superfamily member 5. (300 aa)
	CTSS	Cathepsin S; Belongs to the peptidase C1 family. (168 aa)
	GLB1	Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family. (569 aa)
	DPP4	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (757 aa)
	DPP4-2	Uncharacterized protein; Belongs to the peptidase S9B family. (992 aa)
	CXCR4	C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	SLAMF1	Signaling lymphocytic activation molecule. (331 aa)
	CD81	Tetraspanin. (233 aa)
	CD4	T-cell surface glycoprotein CD4. (551 aa)
	TMPRSS2	Transmembrane protease serine 2; Belongs to the peptidase S1 family. (539 aa)
	NPC1	Niemann-Pick C1 protein. (1300 aa)
	Y1Q_0018238	Actin, clone 302-like; Belongs to the actin family. (398 aa)
	Y1Q_0018253	Uncharacterized protein; Belongs to the peptidase S8 family. (460 aa)
	IRF3	Interferon regulatory factor 3 isoform B. (462 aa)
	ACE2	Angiotensin-converting enzyme. (805 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	CD4	A0A151N089	A0A151MCU8	Angiotensin-converting enzyme.	T-cell surface glycoprotein CD4.	0.496
ACE2	DPP4	A0A151N089	A0A151M0A4	Angiotensin-converting enzyme.	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	0.708
ACE2	DPP4-2	A0A151N089	A0A151M0D2	Angiotensin-converting enzyme.	Uncharacterized protein; Belongs to the peptidase S9B family.	0.790
ACE2	NRP2	A0A151N089	A0A151PCV6	Angiotensin-converting enzyme.	Neuropilin; Belongs to the neuropilin family.	0.621
ACE2	TMPRSS2	A0A151N089	A0A151MED3	Angiotensin-converting enzyme.	Transmembrane protease serine 2; Belongs to the peptidase S1 family.	0.700
ACE2	Y1Q_0018253	A0A151N089	A0A151N609	Angiotensin-converting enzyme.	Uncharacterized protein; Belongs to the peptidase S8 family.	0.665
AXL	CD4	A0A151MP36	A0A151MCU8	Tyrosine-protein kinase receptor UFO isoform B.	T-cell surface glycoprotein CD4.	0.465
AXL	NPC1-2	A0A151MP36	A0A151PHK5	Tyrosine-protein kinase receptor UFO isoform B.	SSD domain-containing protein.	0.418
CD4	ACE2	A0A151MCU8	A0A151N089	T-cell surface glycoprotein CD4.	Angiotensin-converting enzyme.	0.496
CD4	AXL	A0A151MCU8	A0A151MP36	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase receptor UFO isoform B.	0.465
CD4	CD40	A0A151MCU8	A0A151MVS6	T-cell surface glycoprotein CD4.	Tumor necrosis factor receptor superfamily member 5.	0.732
CD4	CD68	A0A151MCU8	A0A151P6V8	T-cell surface glycoprotein CD4.	Macrosialin.	0.860
CD4	CD81	A0A151MCU8	A0A151MCB7	T-cell surface glycoprotein CD4.	Tetraspanin.	0.722
CD4	CLDN1	A0A151MCU8	A0A151MM51	T-cell surface glycoprotein CD4.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.584
CD4	CTSS	A0A151MCU8	A0A151MW96	T-cell surface glycoprotein CD4.	Cathepsin S; Belongs to the peptidase C1 family.	0.451
CD4	CXCR4	A0A151MCU8	A0A151M0R9	T-cell surface glycoprotein CD4.	C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family.	0.824
CD4	DPP4	A0A151MCU8	A0A151M0A4	T-cell surface glycoprotein CD4.	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	0.419
CD4	DPP4-2	A0A151MCU8	A0A151M0D2	T-cell surface glycoprotein CD4.	Uncharacterized protein; Belongs to the peptidase S9B family.	0.589
CD4	IRF3	A0A151MCU8	A0A151N0Z2	T-cell surface glycoprotein CD4.	Interferon regulatory factor 3 isoform B.	0.785
CD4	NRP2	A0A151MCU8	A0A151PCV6	T-cell surface glycoprotein CD4.	Neuropilin; Belongs to the neuropilin family.	0.694