(15 nodes) Glycosphingolipid biosynthesis - ganglio series network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GLB1	Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family. (569 aa)
	ST6GALNAC4	N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D); Belongs to the glycosyltransferase 29 family. (302 aa)
	HEXB	Beta-hexosaminidase. (531 aa)
	ST8SIA5	Alpha-2,8-sialyltransferase 8E isoform A; Belongs to the glycosyltransferase 29 family. (428 aa)
	B4GALNT1	Beta-1,4 N-acetylgalactosaminyltransferase. (537 aa)
	B3GALT4	Hexosyltransferase. (361 aa)
	SLC33A1	Acetyl-coenzyme A transporter 1. (546 aa)
	ST6GALNAC5	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Belongs to the glycosyltransferase 29 family. (337 aa)
	ST6GALNAC3	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (305 aa)
	ST8SIA1-1	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform A; Belongs to the glycosyltransferase 29 family. (381 aa)
	ST3GAL2	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (407 aa)
	GLB1-2	Beta-galactosidase. (651 aa)
	ST3GAL1	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (339 aa)
	ST3GAL5-1	Lactosylceramide alpha-2,3-sialyltransferase isoform B; Belongs to the glycosyltransferase 29 family. (396 aa)
	HEXB-2	Uncharacterized protein. (441 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3GALT4	B4GALNT1	A0A151N8E4	A0A151N3A4	Hexosyltransferase.	Beta-1,4 N-acetylgalactosaminyltransferase.	0.916
B3GALT4	GLB1	A0A151N8E4	A0A151LY90	Hexosyltransferase.	Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family.	0.900
B3GALT4	GLB1-2	A0A151N8E4	A0A151P2K4	Hexosyltransferase.	Beta-galactosidase.	0.900
B3GALT4	HEXB	A0A151N8E4	A0A151ML73	Hexosyltransferase.	Beta-hexosaminidase.	0.904
B3GALT4	HEXB-2	A0A151N8E4	A0A151PHJ1	Hexosyltransferase.	Uncharacterized protein.	0.902
B3GALT4	ST3GAL1	A0A151N8E4	A0A151P860	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family.	0.926
B3GALT4	ST3GAL2	A0A151N8E4	A0A151NJP1	Hexosyltransferase.	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family.	0.926
B4GALNT1	B3GALT4	A0A151N3A4	A0A151N8E4	Beta-1,4 N-acetylgalactosaminyltransferase.	Hexosyltransferase.	0.916
B4GALNT1	GLB1	A0A151N3A4	A0A151LY90	Beta-1,4 N-acetylgalactosaminyltransferase.	Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family.	0.900
B4GALNT1	GLB1-2	A0A151N3A4	A0A151P2K4	Beta-1,4 N-acetylgalactosaminyltransferase.	Beta-galactosidase.	0.900
B4GALNT1	HEXB	A0A151N3A4	A0A151ML73	Beta-1,4 N-acetylgalactosaminyltransferase.	Beta-hexosaminidase.	0.934
B4GALNT1	HEXB-2	A0A151N3A4	A0A151PHJ1	Beta-1,4 N-acetylgalactosaminyltransferase.	Uncharacterized protein.	0.924
B4GALNT1	SLC33A1	A0A151N3A4	A0A151NB00	Beta-1,4 N-acetylgalactosaminyltransferase.	Acetyl-coenzyme A transporter 1.	0.909
B4GALNT1	ST3GAL5-1	A0A151N3A4	A0A151P9A4	Beta-1,4 N-acetylgalactosaminyltransferase.	Lactosylceramide alpha-2,3-sialyltransferase isoform B; Belongs to the glycosyltransferase 29 family.	0.923
B4GALNT1	ST8SIA1-1	A0A151N3A4	A0A151NJL9	Beta-1,4 N-acetylgalactosaminyltransferase.	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform A; Belongs to the glycosyltransferase 29 family.	0.947
B4GALNT1	ST8SIA5	A0A151N3A4	A0A151MWI5	Beta-1,4 N-acetylgalactosaminyltransferase.	Alpha-2,8-sialyltransferase 8E isoform A; Belongs to the glycosyltransferase 29 family.	0.903
GLB1	B3GALT4	A0A151LY90	A0A151N8E4	Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family.	Hexosyltransferase.	0.900
GLB1	B4GALNT1	A0A151LY90	A0A151N3A4	Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family.	Beta-1,4 N-acetylgalactosaminyltransferase.	0.900
GLB1	GLB1-2	A0A151LY90	A0A151P2K4	Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family.	Beta-galactosidase.	0.902
GLB1	HEXB	A0A151LY90	A0A151ML73	Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family.	Beta-hexosaminidase.	0.930