STRINGSTRING
BTG1 BTG1 CNOT4 CNOT4 PNLDC1 PNLDC1 Y1Q_0003408 Y1Q_0003408 CNOT6L CNOT6L DIS3L DIS3L WDR61 WDR61 PATL2-1 PATL2-1 EDC3 EDC3 ENO2-2 ENO2-2 CNOT8 CNOT8 EXOSC2 EXOSC2 PNPT1 PNPT1 LSM3 LSM3 LSM4 LSM4 PABPC1 PABPC1 EXOSC5 EXOSC5 CNOT6L-2 CNOT6L-2 EXOSC8 EXOSC8 CNOT10 CNOT10 PAN3 PAN3 CNOT1 CNOT1 EXOSC3 EXOSC3 EXOSC1 EXOSC1 PATL1 PATL1 SKIV2L2 SKIV2L2 ENO2 ENO2 PARN PARN TOB1 TOB1 ENO1 ENO1 EXOSC10 EXOSC10 RQCD1 RQCD1 HSPD1 HSPD1 XRN1 XRN1 DHX36 DHX36 LSM1 LSM1 BTG2 BTG2 XRN2 XRN2 LSM7 LSM7 NUDT16 NUDT16 ZCCHC7 ZCCHC7 BTG4 BTG4 PAN2 PAN2 DCPS DCPS TOB2 TOB2 PFKP PFKP EDC4 EDC4 DIS3 DIS3 MPHOSPH6 MPHOSPH6 EXOSC4 EXOSC4 HSPA9 HSPA9 PABPC1L PABPC1L LSM5 LSM5 DDX6 DDX6 PFKM PFKM CNOT7 CNOT7 Y1Q_0006955 Y1Q_0006955 LSM6 LSM6 EXOSC9 EXOSC9 CNOT2 CNOT2 LSM8 LSM8 TTC37 TTC37 DCP2 DCP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BTG1Protein BTG1. (170 aa)
CNOT4CCR4-NOT transcription complex subunit 4 isoform A. (762 aa)
PNLDC1Poly(A)-specific ribonuclease PARN-like domain-containing protein 1 isoform B. (534 aa)
Y1Q_0003408Protein BTG3-like. (178 aa)
CNOT6LCCR4-NOT transcription complex subunit 6-like. (627 aa)
DIS3LDIS3-like exonuclease 1; Belongs to the RNR ribonuclease family. (1050 aa)
WDR61WD repeat-containing protein 61. (339 aa)
PATL2-1PAT1-like protein 2 isoform B. (800 aa)
EDC3Enhancer of mRNA-decapping protein 3. (508 aa)
ENO2-2Uncharacterized protein. (849 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
EXOSC2Exosome complex component RRP4. (294 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (769 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (170 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (617 aa)
EXOSC5Exosome complex component RRP46. (200 aa)
CNOT6L-2Endo/exonuclease/phosphatase domain-containing protein. (594 aa)
EXOSC8Exosome complex component RRP43. (269 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (745 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (760 aa)
CNOT1CCR4-NOT transcription complex subunit 1 isoform B. (2350 aa)
EXOSC3Exosome complex component RRP40. (257 aa)
EXOSC1Exosome complex component CSL4. (133 aa)
PATL1PAT1-like protein 1. (770 aa)
SKIV2L2Superkiller viralicidic activity 2-like 2. (1033 aa)
ENO2Gamma-enolase. (386 aa)
PARNPoly(A)-specific ribonuclease PARN. (638 aa)
TOB1Protein Tob1. (323 aa)
ENO1Uncharacterized protein. (470 aa)
EXOSC10Exosome component 10; Belongs to the spermidine/spermine synthase family. (1132 aa)
RQCD1Cell differentiation RCD1-like protein isoform A. (309 aa)
HSPD1Heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (519 aa)
XRN15'-3' exoribonuclease 1. (1728 aa)
DHX36ATP-dependent RNA helicase DHX36. (991 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
BTG2Protein BTG2. (152 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (955 aa)
LSM7U6 snRNA-associated Sm-like protein LSm7. (110 aa)
NUDT16U8 snoRNA-decapping enzyme. (218 aa)
ZCCHC7Zinc finger CCHC domain-containing protein 7. (495 aa)
BTG4Protein BTG4. (232 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1115 aa)
DCPSM7GpppX diphosphatase. (303 aa)
TOB2Protein Tob2. (336 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (781 aa)
EDC4Enhancer of mRNA-decapping protein 4. (1375 aa)
DIS3Exosome complex exonuclease RRP44; Belongs to the RNR ribonuclease family. (960 aa)
MPHOSPH6M-phase phosphoprotein 6. (149 aa)
EXOSC4Exosome complex component RRP41. (188 aa)
HSPA9Uncharacterized protein; Belongs to the heat shock protein 70 family. (672 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (580 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
DDX6Putative ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family. (483 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (841 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (262 aa)
Y1Q_0006955Anti_prolifrtn domain-containing protein. (80 aa)
LSM6U6 snRNA-associated Sm-like protein LSm6. (105 aa)
EXOSC9Exosome complex component RRP45. (439 aa)
CNOT2CCR4-NOT transcription complex subunit 2 isoform A. (561 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
TTC37Tetratricopeptide repeat protein 37. (1582 aa)
DCP2M7GpppN-mRNA hydrolase isoform B. (418 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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