99 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CALM1	Calmodulin; Belongs to the calmodulin family. (149 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1017 aa)
	ANAPC1	Anaphase-promoting complex subunit 1. (1942 aa)
	BUB1	Mitotic checkpoint serine/threonine-protein kinase BUB1. (1069 aa)
	PPP2R5E	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (515 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (733 aa)
	SMC1A-2	Structural maintenance of chromosomes protein. (1233 aa)
	CPEB4	Cytoplasmic polyadenylation element-binding protein 4. (345 aa)
	PTTG1	Securin. (195 aa)
	PPP2CA	Serine/threonine-protein phosphatase; Belongs to the SKP1 family. (474 aa)
	CAMK2G	Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform B; Belongs to the protein kinase superfamily. (489 aa)
	CALML4	Calmodulin-like protein 4. (153 aa)
	MAP2K1-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1363 aa)
	CCNB2	G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (398 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (147 aa)
	PPP2R1A	Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform. (643 aa)
	PPP2R5D	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (596 aa)
	ANAPC2	Anaphase-promoting complex subunit 2; Belongs to the cullin family. (675 aa)
	CDC26	Anaphase-promoting complex subunit CDC26. (84 aa)
	PPP3R1	Calcineurin subunit B type 1. (170 aa)
	CDC25C	M-phase inducer phosphatase 3 isoform B. (470 aa)
	CDC23	Cell division cycle 23-like protein isoform B. (585 aa)
	CDK2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (1680 aa)
	CPEB1	Cytoplasmic polyadenylation element-binding protein 1 isoform D. (595 aa)
	YWHAE	14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
	MOS	Proto-oncogene serine/threonine-protein kinase mos; Belongs to the protein kinase superfamily. (350 aa)
	Y1Q_0013899	Uncharacterized protein. (103 aa)
	ITPR2-2	Uncharacterized protein. (2702 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1074 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (509 aa)
	PPP2R5B	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (493 aa)
	PPP1CA-2	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	ADCY6	Uncharacterized protein. (1272 aa)
	CDK1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
	YWHAZ	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (319 aa)
	CCNE2-1	G1/S-specific cyclin-E2 isoform B; Belongs to the cyclin family. (410 aa)
	FBXO43	F-box only protein 43. (214 aa)
	ANAPC10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (179 aa)
	RPS6KA3	Non-specific serine/threonine protein kinase. (914 aa)
	MAD1L1	Mitotic spindle assembly checkpoint protein MAD1 isoform B. (1005 aa)
	CALML6	Calmodulin-like protein 6. (159 aa)
	MAD2L2	Mitotic spindle assembly checkpoint protein MAD2B. (228 aa)
	YWHAH	14-3-3 protein eta; Belongs to the 14-3-3 family. (247 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	YWHAG	14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
	CCNE1	G1/S-specific cyclin-E1; Belongs to the cyclin family. (408 aa)
	YWHAQ	14-3-3 protein theta; Belongs to the 14-3-3 family. (267 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	PPP3CC-2	Serine/threonine-protein phosphatase. (1065 aa)
	ADCY2-2	Guanylate cyclase domain-containing protein. (226 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (104 aa)
	IGF1	Insulin-like growth factor I. (153 aa)
	PLCZ1	Phosphoinositide phospholipase C. (652 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily. (368 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (758 aa)
	Y1Q_0006499	Uncharacterized protein; Belongs to the protein kinase superfamily. (401 aa)
	FBXO5	F-box only protein 5. (431 aa)
	REC8-1	Meiotic recombination REC8-like protein isoform B. (528 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (511 aa)
	AR	Androgen receptor. (634 aa)
	RPS6KA6-2	Ribosomal protein S6 kinase. (747 aa)
	Y1Q_0023495	Calmodulin-alpha-like; Belongs to the calmodulin family. (149 aa)
	STAG3	SCD domain-containing protein. (858 aa)
	ANAPC11	Anaphase-promoting complex subunit 11. (98 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
	ANAPC7	Anaphase-promoting complex subunit 7. (608 aa)
	ANAPC5	Anaphase-promoting complex subunit 5. (756 aa)
	Y1Q_0020451	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (281 aa)
	SLK	Uncharacterized protein. (1281 aa)
	SMC3	Structural maintenance of chromosomes protein. (1235 aa)
	PLK1	Serine/threonine-protein kinase PLK. (664 aa)
	CDC16	Cell division cycle 16-like protein. (622 aa)
	AURKA	Aurora kinase A; Belongs to the protein kinase superfamily. (450 aa)
	YWHAB	14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (300 aa)
	CALM3	Uncharacterized protein; Belongs to the calmodulin family. (78 aa)
	ADCY3-2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1124 aa)
	ADCY1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (776 aa)
	SPDYA	Speedy protein A. (243 aa)
	PPP2R5C	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (479 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (347 aa)
	ITPR3	Uncharacterized protein. (2667 aa)
	ESPL1	Separin. (2192 aa)
	CDC20	Cell division cycle 20-like protein. (427 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1238 aa)
	PGR-1	Progesterone receptor isoform B. (408 aa)
	PPP2R5C-2	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (602 aa)
	CPEB2	Uncharacterized protein. (495 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (796 aa)
	CDC27	Cell division cycle 27-like protein. (834 aa)
	PKMYT1	Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase. (554 aa)
	MAD2L1	Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
	MAPK12	Mitogen-activated protein kinase. (309 aa)
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (959 aa)
	CCNB1	G2/mitotic-specific cyclin-B1 isoform B; Belongs to the cyclin family. (411 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	A0A151P235	A0A151PGT0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.449
ADCY1	ADCY2-2	A0A151P235	A0A151NCX3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein.	0.429
ADCY1	ADCY3	A0A151P235	A0A151M126	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.459
ADCY1	ADCY3-2	A0A151P235	A0A151P1B5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.948
ADCY1	ADCY6	A0A151P235	A0A151MUF3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.460
ADCY1	ADCY7	A0A151P235	A0A151MRZ2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.455
ADCY1	CALM1	A0A151P235	A0A0Q3ZXL6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin; Belongs to the calmodulin family.	0.958
ADCY1	CALM3	A0A151P235	A0A151P0Z1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.959
ADCY1	CALML4	A0A151P235	A0A151M8V9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like protein 4.	0.942
ADCY1	CALML6	A0A151P235	A0A151N3P5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like protein 6.	0.952
ADCY1	PRKACB	A0A151P235	A0A151NJ28	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily.	0.961
ADCY1	Y1Q_0006499	A0A151P235	A0A151NKT3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.961
ADCY1	Y1Q_0023495	A0A151P235	A0A151NPX3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-alpha-like; Belongs to the calmodulin family.	0.959
ADCY2	ADCY1	A0A151PGT0	A0A151P235	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.449
ADCY2	ADCY3	A0A151PGT0	A0A151M126	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.638
ADCY2	ADCY6	A0A151PGT0	A0A151MUF3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.640
ADCY2	PRKACB	A0A151PGT0	A0A151NJ28	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily.	0.930
ADCY2	Y1Q_0006499	A0A151PGT0	A0A151NKT3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.930
ADCY2-2	ADCY1	A0A151NCX3	A0A151P235	Guanylate cyclase domain-containing protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY2-2	ADCY3	A0A151NCX3	A0A151M126	Guanylate cyclase domain-containing protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.628