STRINGSTRING
GLB1 GLB1 SLC11A2 SLC11A2 Y1Q_0011740 Y1Q_0011740 IGF2R IGF2R CTSK CTSK Y1Q_0010431 Y1Q_0010431 LAMP3-1 LAMP3-1 MCOLN1 MCOLN1 CTSL CTSL Y1Q_0007013 Y1Q_0007013 AP4E1 AP4E1 CTSE CTSE ACP2 ACP2 CTSD CTSD HYAL1 HYAL1 HYAL2 HYAL2 HYAL3-1 HYAL3-1 ABCA2 ABCA2 GNPTG GNPTG HGSNAT HGSNAT CD164-1 CD164-1 SUMF1 SUMF1 HEXB HEXB NEU1 NEU1 CLTCL1 CLTCL1 TAP2 TAP2 FUCA1 FUCA1 PPT1 PPT1 DNASE2 DNASE2 TCIRG1 TCIRG1 SCARB2 SCARB2 ATP6V1H ATP6V1H PLA2G15 PLA2G15 CTSAL CTSAL AP3M1 AP3M1 BMS1-2 BMS1-2 CTSH CTSH GALNS GALNS CTSC CTSC CTSS CTSS TPP1 TPP1 SLC11A1 SLC11A1 CLTB-1 CLTB-1 AP1S2-1 AP1S2-1 LITAF LITAF LITAFL LITAFL ARSG ARSG GGA1L GGA1L AP1B1 AP1B1 GUSB GUSB NAGPA NAGPA CLTC CLTC IDS IDS SORT1 SORT1 GBA GBA NAGLU NAGLU CTNS CTNS AP1S3 AP1S3 ATP6AP1 ATP6AP1 MAN2B1 MAN2B1 ATP6V0D1 ATP6V0D1 AP3M2 AP3M2 ATP6V0B ATP6V0B CLTA CLTA IDUA IDUA Y1Q_0020688 Y1Q_0020688 Y1Q_0013147 Y1Q_0013147 Y1Q_0013148 Y1Q_0013148 AP4B1 AP4B1 NAGA NAGA Y1Q_0013149 Y1Q_0013149 GGA1 GGA1 ATP6V0A4 ATP6V0A4 NPC2 NPC2 GAA GAA CD63 CD63 GM2A GM2A AP4S1 AP4S1 SGSH SGSH CLN5 CLN5 FUCA2 FUCA2 MANBA MANBA ACP5 ACP5 GLA GLA LAMP2-1 LAMP2-1 ATP6V0A2 ATP6V0A2 AP1M2 AP1M2 Y1Q_0019890 Y1Q_0019890 CTSB CTSB CLN3 CLN3 LAMP1 LAMP1 EARS2 EARS2 CTSZ CTSZ AP1M1 AP1M1 Y1Q_0022212 Y1Q_0022212 Y1Q_0022217 Y1Q_0022217 PSAP-2 PSAP-2 Y1Q_0022210 Y1Q_0022210 LIPA LIPA CTSG CTSG AP1S1 AP1S1 Y1Q_0000231 Y1Q_0000231 CTSA CTSA Y1Q_0022211 Y1Q_0022211 PSAP-1 PSAP-1 GLB1-2 GLB1-2 CTSW CTSW ENTPD4 ENTPD4 M6PR M6PR SMPD1 SMPD1 CD68 CD68 ARSA ARSA LGMN LGMN ASAH1 ASAH1 AGA AGA CTSO-1 CTSO-1 ATP6V0A1 ATP6V0A1 MFSD8 MFSD8 HYAL6 HYAL6 HYAL4 HYAL4 Y1Q_0019660 Y1Q_0019660 SPAM1-1 SPAM1-1 GNS GNS NOTS NOTS AP4M1 AP4M1 LAPTM5 LAPTM5 ATP6V0D2 ATP6V0D2 HEXB-2 HEXB-2 NPC1-2 NPC1-2 AP3B1 AP3B1 ARSB ARSB AP3S1 AP3S1 PPT2 PPT2 LAPTM4A LAPTM4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLB1Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family. (569 aa)
SLC11A2Uncharacterized protein. (611 aa)
Y1Q_0011740Tetraspanin. (244 aa)
IGF2RCation-independent mannose-6-phosphate receptor. (2470 aa)
CTSKCathepsin K isoform B; Belongs to the peptidase C1 family. (388 aa)
Y1Q_0010431Major facilitator superfamily domain-containing protein 8-like. (516 aa)
LAMP3-1Lysosome-associated membrane glycoprotein 3 isoform A. (422 aa)
MCOLN1Mucolipin-1 isoform B. (617 aa)
CTSLCathepsin L1; Belongs to the peptidase C1 family. (317 aa)
Y1Q_0007013Clat_adaptor_s domain-containing protein. (160 aa)
AP4E1AP-4 complex subunit epsilon-1 isoform A. (1148 aa)
CTSECathepsin E; Belongs to the peptidase A1 family. (392 aa)
ACP2Lysosomal acid phosphatase; Belongs to the histidine acid phosphatase family. (390 aa)
CTSDCathepsin D; Belongs to the peptidase A1 family. (405 aa)
HYAL1Hyaluronidase. (445 aa)
HYAL2Hyaluronidase. (474 aa)
HYAL3-1Hyaluronidase. (644 aa)
ABCA2Uncharacterized protein. (2511 aa)
GNPTGN-acetylglucosamine-1-phosphotransferase subunit gamma. (258 aa)
HGSNATHeparan-alpha-glucosaminide N-acetyltransferase isoform A. (627 aa)
CD164-1Sialomucin core protein 24 isoform A. (210 aa)
SUMF1Sulfatase-modifying factor 1. (351 aa)
HEXBBeta-hexosaminidase. (531 aa)
NEU1Sialidase-1. (242 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1672 aa)
TAP2Antigen peptide transporter 2. (580 aa)
FUCA1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (452 aa)
PPT1Palmitoyl-protein thioesterase 1. (266 aa)
DNASE2Deoxyribonuclease-2-beta. (383 aa)
TCIRG1V-type proton ATPase subunit a. (1063 aa)
SCARB2Lysosome membrane protein 2; Belongs to the CD36 family. (482 aa)
ATP6V1HV-type proton ATPase subunit H. (514 aa)
PLA2G15Group XV phospholipase A2. (406 aa)
CTSALCarboxypeptidase; Belongs to the peptidase S10 family. (642 aa)
AP3M1MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (418 aa)
BMS1-2Heparan-alpha-glucosaminide N-acetyltransferase-like. (496 aa)
CTSHPro-cathepsin H; Belongs to the peptidase C1 family. (334 aa)
GALNSN-acetylgalactosamine-6-sulfatase. (505 aa)
CTSCDipeptidyl peptidase 1; Belongs to the peptidase C1 family. (475 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (168 aa)
TPP1Tripeptidyl-peptidase 1. (428 aa)
SLC11A1Natural resistance-associated macrophage protein 1. (635 aa)
CLTB-1Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (220 aa)
AP1S2-1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (161 aa)
LITAFLipopolysaccharide-induced tumor necrosis factor-alpha factor. (116 aa)
LITAFLLipopolysaccharide-induced tumor necrosis factor-alpha factor. (174 aa)
ARSGArylsulfatase G isoform A. (544 aa)
GGA1LADP-ribosylation factor-binding protein GGA1. (752 aa)
AP1B1AP complex subunit beta. (970 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (644 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (451 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1744 aa)
IDSIduronate 2-sulfatase. (545 aa)
SORT1Sortilin. (773 aa)
GBAGlucosylceramidase. (779 aa)
NAGLUAlpha-N-acetylglucosaminidase. (620 aa)
CTNSCystinosin. (367 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
ATP6AP1V-type proton ATPase subunit S1. (434 aa)
MAN2B1Alpha-mannosidase. (985 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
AP3M2AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family. (418 aa)
ATP6V0BV-type proton ATPase proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (226 aa)
IDUAAlpha-L-iduronidase. (549 aa)
Y1Q_0020688Glucosylceramidase. (347 aa)
Y1Q_0013147Peptidase S1 domain-containing protein. (164 aa)
Y1Q_0013148Mast cell protease 3-like; Belongs to the peptidase S1 family. (167 aa)
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (718 aa)
NAGAAlpha-galactosidase. (511 aa)
Y1Q_0013149Mast cell protease 1A-like. (71 aa)
GGA1ADP-ribosylation factor-binding protein GGA1. (669 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa)
NPC2Epididymal secretory protein E1. (150 aa)
GAALysosomal alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family. (915 aa)
CD63Tetraspanin. (240 aa)
GM2AGanglioside GM2 activator. (191 aa)
AP4S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (138 aa)
SGSHN-sulfoglucosamine sulfohydrolase. (415 aa)
CLN5Ceroid-lipofuscinosis neuronal protein 5. (335 aa)
FUCA2Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (453 aa)
MANBABeta-mannosidase; Belongs to the ubiquitin-conjugating enzyme family. (1003 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (272 aa)
GLAAlpha-galactosidase. (431 aa)
LAMP2-1Lysosome-associated membrane glycoprotein 2 isoform C. (470 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (841 aa)
AP1M2MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (425 aa)
Y1Q_0019890Cathepsin D-like; Belongs to the peptidase A1 family. (395 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (400 aa)
CLN3Battenin. (460 aa)
LAMP1Lysosome-associated membrane glycoprotein 1. (420 aa)
EARS2Putative glutamate--tRNA ligase, mitochondrial. (1101 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
AP1M1AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (423 aa)
Y1Q_0022212Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (405 aa)
Y1Q_0022217Lysosomal acid lipase/cholesteryl ester hydrolase-like. (365 aa)
PSAP-2Prosaposin. (529 aa)
Y1Q_0022210Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (403 aa)
LIPALysosomal acid lipase/cholesteryl ester hydrolase isoform B. (456 aa)
CTSGMast cell protease 1A; Belongs to the peptidase S1 family. (242 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (128 aa)
Y1Q_0000231Cathepsin L1-like; Belongs to the peptidase C1 family. (334 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (376 aa)
Y1Q_0022211Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (368 aa)
PSAP-1Prosaposin isoform B. (529 aa)
GLB1-2Beta-galactosidase. (651 aa)
CTSWCathepsin W; Belongs to the peptidase C1 family. (457 aa)
ENTPD4Ectonucleoside triphosphate diphosphohydrolase 4 isoform B; Belongs to the GDA1/CD39 NTPase family. (616 aa)
M6PRCation-dependent mannose-6-phosphate receptor. (308 aa)
SMPD1Sphingomyelin phosphodiesterase. (287 aa)
CD68Macrosialin. (403 aa)
ARSAArylsulfatase A. (384 aa)
LGMNLegumain. (470 aa)
ASAH1Acid ceramidase; Belongs to the acid ceramidase family. (395 aa)
AGAN(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase isoform A. (349 aa)
CTSO-1Cathepsin O isoform B; Belongs to the peptidase C1 family. (318 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
MFSD8Major facilitator superfamily domain-containing protein 8. (528 aa)
HYAL6Hyaluronidase. (454 aa)
HYAL4Hyaluronidase. (507 aa)
Y1Q_0019660Uncharacterized protein. (458 aa)
SPAM1-1Hyaluronidase. (464 aa)
GNSN-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (531 aa)
NOTSNothepsin isoform A; Belongs to the peptidase A1 family. (403 aa)
AP4M1AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (218 aa)
LAPTM5Lysosomal-associated transmembrane protein 5. (258 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
HEXB-2Uncharacterized protein. (441 aa)
NPC1-2SSD domain-containing protein. (1281 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1114 aa)
ARSBArylsulfatase B. (379 aa)
AP3S1AP-3 complex subunit sigma-1. (193 aa)
PPT2Lysosomal thioesterase PPT2. (230 aa)
LAPTM4ALysosomal-associated transmembrane protein 4A. (229 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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