(18 nodes) Prostate gland development network (Crocodylus porosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AR	Androgen receptor. (681 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	HOXB13	Homeobox B13. (296 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (508 aa)
	EAF2	ELL associated factor 2. (276 aa)
	FEM1B	Fem-1 homolog B. (797 aa)
	ESR1	Estrogen receptor 1. (587 aa)
	CYP7B1	25-hydroxycholesterol 7-alpha-hydroxylase. (501 aa)
	HOXA13	Homeobox A13. (305 aa)
	ENSCPRP00005023167	annotation not available (92 aa)
	HOXA10	Homeobox A10. (271 aa)
	SERPINF1	Serpin family F member 1. (417 aa)
	WDR77	WD repeat domain 77. (460 aa)
	STK11	Serine/threonine kinase 11. (440 aa)
	HOXD13	Homeobox D13. (339 aa)
	TNC	Tenascin C. (2272 aa)
	TP63	Tumor protein p63. (647 aa)
	UBE3A	Ubiquitin protein ligase E3A. (911 aa)

Your Current Organism:

Crocodylus porosus

NCBI taxonomy Id: 8502
Other names: Australian saltwater crocodile, C. porosus, ZMB 278, estuarine crocodile

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	CTNNB1	ENSCPRP00005012750	ENSCPRP00005012052	Androgen receptor.	Catenin beta 1.	0.902
AR	ESR1	ENSCPRP00005012750	ENSCPRP00005026190	Androgen receptor.	Estrogen receptor 1.	0.625
AR	HOXB13	ENSCPRP00005012750	ENSCPRP00005010170	Androgen receptor.	Homeobox B13.	0.445
AR	UBE3A	ENSCPRP00005012750	ENSCPRP00005016761	Androgen receptor.	Ubiquitin protein ligase E3A.	0.487
AR	WDR77	ENSCPRP00005012750	ENSCPRP00005022745	Androgen receptor.	WD repeat domain 77.	0.465
CTNNB1	AR	ENSCPRP00005012052	ENSCPRP00005012750	Catenin beta 1.	Androgen receptor.	0.902
CTNNB1	ESR1	ENSCPRP00005012052	ENSCPRP00005026190	Catenin beta 1.	Estrogen receptor 1.	0.641
CTNNB1	UBE3A	ENSCPRP00005012052	ENSCPRP00005016761	Catenin beta 1.	Ubiquitin protein ligase E3A.	0.881
ENSCPRP00005023167	HOXA10	ENSCPRP00005023167	ENSCPRP00005023160	annotation not available	Homeobox A10.	0.861
ESR1	AR	ENSCPRP00005026190	ENSCPRP00005012750	Estrogen receptor 1.	Androgen receptor.	0.625
ESR1	CTNNB1	ENSCPRP00005026190	ENSCPRP00005012052	Estrogen receptor 1.	Catenin beta 1.	0.641
ESR1	UBE3A	ENSCPRP00005026190	ENSCPRP00005016761	Estrogen receptor 1.	Ubiquitin protein ligase E3A.	0.778
HOXA10	ENSCPRP00005023167	ENSCPRP00005023160	ENSCPRP00005023167	Homeobox A10.	annotation not available	0.861
HOXB13	AR	ENSCPRP00005010170	ENSCPRP00005012750	Homeobox B13.	Androgen receptor.	0.445
STK11	TP63	ENSCPRP00005022295	ENSCPRP00005018050	Serine/threonine kinase 11.	Tumor protein p63.	0.518
TP63	STK11	ENSCPRP00005018050	ENSCPRP00005022295	Tumor protein p63.	Serine/threonine kinase 11.	0.518
TP63	UBE3A	ENSCPRP00005018050	ENSCPRP00005016761	Tumor protein p63.	Ubiquitin protein ligase E3A.	0.661
UBE3A	AR	ENSCPRP00005016761	ENSCPRP00005012750	Ubiquitin protein ligase E3A.	Androgen receptor.	0.487
UBE3A	CTNNB1	ENSCPRP00005016761	ENSCPRP00005012052	Ubiquitin protein ligase E3A.	Catenin beta 1.	0.881
UBE3A	ESR1	ENSCPRP00005016761	ENSCPRP00005026190	Ubiquitin protein ligase E3A.	Estrogen receptor 1.	0.778