(8 nodes) D-Glutamine and D-glutamate metabolism network (Streptomyces turgidiscabies)

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Your Input:
	murD	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (480 aa)
	murC_1	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (462 aa)
	gdhA	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (396 aa)
	murC_2	UDP-N-acetylmuramate--L-alanine ligase. (471 aa)
	murI	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (256 aa)
	glsA	Thermolabile glutaminase; Belongs to the glutaminase family. (318 aa)
	T45_08140	Hypothetical protein; Belongs to the D-glutamate cyclase family. (273 aa)
	purQ	Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (226 aa)

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
gdhA	glsA	T45_05576	T45_07097	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Thermolabile glutaminase; Belongs to the glutaminase family.	0.906
gdhA	murI	T45_05576	T45_07073	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.915
gdhA	purQ	T45_05576	T45_08710	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]	0.898
glsA	gdhA	T45_07097	T45_05576	Thermolabile glutaminase; Belongs to the glutaminase family.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.906
glsA	murD	T45_07097	T45_03985	Thermolabile glutaminase; Belongs to the glutaminase family.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.894
glsA	murI	T45_07097	T45_07073	Thermolabile glutaminase; Belongs to the glutaminase family.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.919
murC_1	murD	T45_02741	T45_03985	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.997
murC_1	murI	T45_02741	T45_07073	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.510
murC_2	murD	T45_06190	T45_03985	UDP-N-acetylmuramate--L-alanine ligase.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.984
murC_2	murI	T45_06190	T45_07073	UDP-N-acetylmuramate--L-alanine ligase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.410
murD	glsA	T45_03985	T45_07097	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Thermolabile glutaminase; Belongs to the glutaminase family.	0.894
murD	murC_1	T45_03985	T45_02741	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.997
murD	murC_2	T45_03985	T45_06190	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	UDP-N-acetylmuramate--L-alanine ligase.	0.984
murD	murI	T45_03985	T45_07073	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.987
murD	purQ	T45_03985	T45_08710	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]	0.891
murI	gdhA	T45_07073	T45_05576	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.915
murI	glsA	T45_07073	T45_07097	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Thermolabile glutaminase; Belongs to the glutaminase family.	0.919
murI	murC_1	T45_07073	T45_02741	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.510
murI	murC_2	T45_07073	T45_06190	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	UDP-N-acetylmuramate--L-alanine ligase.	0.410
murI	murD	T45_07073	T45_03985	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.987