STRINGSTRING
AEF98889.1 AEF98889.1 AEF98890.1 AEF98890.1 uppP uppP xseA xseA uppS uppS dxr dxr AEG00250.1 AEG00250.1 AEG00464.1 AEG00464.1 AEG00465.1 AEG00465.1 ispG ispG ispH ispH ispD ispD ispF ispF xseB xseB AEG01834.1 AEG01834.1 dxs dxs dxs-2 dxs-2 ispE ispE rsmA rsmA AEG02739.1 AEG02739.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
AEF98889.1TIGRFAM: Hopanoid biosynthesis associated RND transporter like protein HpnN; KEGG: nmu:Nmul_A1652 hypothetical protein. (894 aa)
AEF98890.1KEGG: CACA family Na+/Ca+ antiporter; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like; PFAM: Sodium/calcium exchanger membrane region. (324 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (275 aa)
xseAExodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (447 aa)
uppSUndecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (254 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (394 aa)
AEG00250.1Phosphoesterase PA-phosphatase related protein; KEGG: mca:MCA2985 PAP2 superfamily protein; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase. (173 aa)
AEG00464.1PFAM: NUDIX hydrolase domain; KEGG: ote:Oter_2376 NUDIX hydrolase. (167 aa)
AEG00465.1Regulatory protein TetR; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: abo:ABO_0054 TetR family transcriptional regulator. (209 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (406 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (318 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (234 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa)
xseBExodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (64 aa)
AEG01834.1KEGG: mca:MCA0818 geranyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (297 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (620 aa)
dxs-21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (620 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (285 aa)
rsmARibosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (263 aa)
AEG02739.1PFAM: Polyprenyl synthetase; KEGG: nth:Nther_1254 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (322 aa)
Your Current Organism:
Methylomonas methanica
NCBI taxonomy Id: 857087
Other names: M. methanica MC09, Methylomonas methanica MC09, Methylomonas methanica str. MC09, Methylomonas methanica strain MC09
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