STRINGSTRING
AEF98599.1 AEF98599.1 AEF98623.1 AEF98623.1 AEF98690.1 AEF98690.1 dsbB dsbB AEF99403.1 AEF99403.1 msrA msrA AEG00061.1 AEG00061.1 AEG00156.1 AEG00156.1 AEG00157.1 AEG00157.1 dsbD dsbD AEG00159.1 AEG00159.1 prmA prmA AEG00164.1 AEG00164.1 AEG00165.1 AEG00165.1 AEG00166.1 AEG00166.1 AEG00288.1 AEG00288.1 AEG00744.1 AEG00744.1 AEG00745.1 AEG00745.1 AEG00746.1 AEG00746.1 AEG00747.1 AEG00747.1 ccmE ccmE AEG00749.1 AEG00749.1 ccmC ccmC AEG00751.1 AEG00751.1 ccmA ccmA AEG01094.1 AEG01094.1 AEG01405.1 AEG01405.1 AEG02242.1 AEG02242.1 tpx tpx msrB msrB AEG02684.1 AEG02684.1 AEG02691.1 AEG02691.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEF98599.1PFAM: DSBA oxidoreductase; KEGG: mca:MCA2602 thiol:disulfide interchange protein DsbA. (201 aa)
AEF98623.1Protein-disulfide reductase; KEGG: lil:LA_1321 disulfide interchange transmembrane protein; PFAM: Cytochrome c assembly protein, transmembrane region. (636 aa)
AEF98690.1Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (193 aa)
dsbBDisulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (169 aa)
AEF99403.1Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (173 aa)
msrAPeptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (209 aa)
AEG00061.1Disulfide bond isomerase, DsbC/G; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (236 aa)
AEG00156.1PFAM: FxsA cytoplasmic membrane protein; KEGG: tgr:Tgr7_0437 FxsA cytoplasmic membrane protein. (150 aa)
AEG00157.1PFAM: Divalent ion tolerance protein, CutA1; KEGG: noc:Noc_1056 CutA1 divalent ion tolerance protein. (105 aa)
dsbDThiol:disulfide interchange protein dsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (738 aa)
AEG00159.1Redoxin domain protein; PFAM: Redoxin; KEGG: nmu:Nmul_A2682 thioredoxin. (175 aa)
prmARibosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (294 aa)
AEG00164.1KEGG: mca:MCA1048 hypothetical protein. (212 aa)
AEG00165.1KEGG: mca:MCA1049 hypothetical protein; PFAM: RNA cap guanine-N2 methyltransferase; SMART: Pseudouridine synthase/archaeosine transglycosylase. (398 aa)
AEG00166.1KEGG: mca:MCA2501 hypothetical protein. (184 aa)
AEG00288.1Hypothetical protein; KEGG: nwa:Nwat_2778 signal peptide protein. (162 aa)
AEG00744.1KEGG: gca:Galf_1765 cytochrome c-type biogenesis protein CcmI; TIGRFAM: Cytochrome c-type biogenesis protein CcmI; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-3. (381 aa)
AEG00745.1Cytochrome C biogenesis protein; Possible subunit of a heme lyase. (153 aa)
AEG00746.1KEGG: pna:Pnap_0584 periplasmic protein thiol--disulphide oxidoreductase DsbE; TIGRFAM: Periplasmic protein thiol:disulphide oxidoreductase DsbE; PFAM: Redoxin. (179 aa)
AEG00747.1KEGG: gca:Galf_1768 cytochrome c-type biogenesis protein CcmF; TIGRFAM: Cytochrome c-type biogenesis protein CcmF; PFAM: Cytochrome c assembly protein. (649 aa)
ccmECytochrome c-type biogenesis protein ccmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (144 aa)
AEG00749.1Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (54 aa)
ccmCHeme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (253 aa)
AEG00751.1Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (224 aa)
ccmAHeme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (210 aa)
AEG01094.1Redoxin domain protein; PFAM: Redoxin; KEGG: noc:Noc_1223 hypothetical protein. (167 aa)
AEG01405.1TIGRFAM: Thioredoxin reductase; KEGG: mca:MCA1694 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (318 aa)
AEG02242.1Thioredoxin; KEGG: nmu:Nmul_A0053 thioredoxin; TIGRFAM: Thioredoxin; PFAM: Thioredoxin domain. (144 aa)
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (168 aa)
msrBPeptide methionine sulfoxide reductase msrB; PFAM: Methionine sulphoxide reductase B; TIGRFAM: Methionine sulphoxide reductase B; HAMAP: Peptide methionine sulfoxide reductase msrB; KEGG: pmy:Pmen_2521 methionine sulfoxide reductase B. (131 aa)
AEG02684.1Thioredoxin; KEGG: mca:MCA0057 thioredoxin; TIGRFAM: Thioredoxin; PFAM: Thioredoxin domain; Belongs to the thioredoxin family. (108 aa)
AEG02691.1Peroxiredoxin; KEGG: hch:HCH_04994 peroxiredoxin; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin, C-terminal. (200 aa)
Your Current Organism:
Methylomonas methanica
NCBI taxonomy Id: 857087
Other names: M. methanica MC09, Methylomonas methanica MC09, Methylomonas methanica str. MC09, Methylomonas methanica strain MC09
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