(12 nodes) Trimeric LpxA-like superfamily network (Methylomonas methanica)

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Your Input:
	AEF98857.1	Hypothetical protein; KEGG: pph:Ppha_0561 putative acetyltransferase. (181 aa)
	AEF99619.1	KEGG: vsp:VS_0225 putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ. (200 aa)
	glgC	Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (426 aa)
	AEF99983.1	PFAM: Bacterial transferase hexapeptide repeat; KEGG: csa:Csal_0401 anhydrase family 3 protein. (175 aa)
	AEG00274.1	PFAM: Bacterial transferase hexapeptide repeat; KEGG: rle:RL3644 putative polysaccharide acetyltransferase protein. (157 aa)
	lpxD	UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (342 aa)
	lpxA	Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (256 aa)
	AEG01484.1	KEGG: mca:MCA1830 serine acetyltransferase; TIGRFAM: Serine O-acetyltransferase. (259 aa)
	AEG02272.1	KEGG: mca:MCA2611 serine acetyltransferase; TIGRFAM: Serine O-acetyltransferase. (249 aa)
	AEG02315.1	TIGRFAM: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; KEGG: mca:MCA0397 UDP-N-acetylglucosamine acyltransferase; PFAM: Bacterial transferase hexapeptide repeat. (258 aa)
	dapD	TIGRFAM: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; HAMAP: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; KEGG: mca:MCA1490 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (272 aa)
	glmU	Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa)

Your Current Organism:

Methylomonas methanica

NCBI taxonomy Id: 857087
Other names: M. methanica MC09, Methylomonas methanica MC09, Methylomonas methanica str. MC09, Methylomonas methanica strain MC09

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEG01484.1	AEG02272.1	Metme_3106	Metme_3918	KEGG: mca:MCA1830 serine acetyltransferase; TIGRFAM: Serine O-acetyltransferase.	KEGG: mca:MCA2611 serine acetyltransferase; TIGRFAM: Serine O-acetyltransferase.	0.906
AEG02272.1	AEG01484.1	Metme_3918	Metme_3106	KEGG: mca:MCA2611 serine acetyltransferase; TIGRFAM: Serine O-acetyltransferase.	KEGG: mca:MCA1830 serine acetyltransferase; TIGRFAM: Serine O-acetyltransferase.	0.906
AEG02315.1	glmU	Metme_3961	Metme_4503	TIGRFAM: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; KEGG: mca:MCA0397 UDP-N-acetylglucosamine acyltransferase; PFAM: Bacterial transferase hexapeptide repeat.	Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.846
AEG02315.1	lpxA	Metme_3961	Metme_2639	TIGRFAM: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; KEGG: mca:MCA0397 UDP-N-acetylglucosamine acyltransferase; PFAM: Bacterial transferase hexapeptide repeat.	Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.913
AEG02315.1	lpxD	Metme_3961	Metme_2562	TIGRFAM: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; KEGG: mca:MCA0397 UDP-N-acetylglucosamine acyltransferase; PFAM: Bacterial transferase hexapeptide repeat.	UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.	0.837
dapD	glmU	Metme_4092	Metme_4503	TIGRFAM: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; HAMAP: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; KEGG: mca:MCA1490 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.	Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.411
glmU	AEG02315.1	Metme_4503	Metme_3961	Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	TIGRFAM: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; KEGG: mca:MCA0397 UDP-N-acetylglucosamine acyltransferase; PFAM: Bacterial transferase hexapeptide repeat.	0.846
glmU	dapD	Metme_4503	Metme_4092	Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	TIGRFAM: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; HAMAP: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; KEGG: mca:MCA1490 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.	0.411
glmU	lpxA	Metme_4503	Metme_2639	Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.846
lpxA	AEG02315.1	Metme_2639	Metme_3961	Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	TIGRFAM: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; KEGG: mca:MCA0397 UDP-N-acetylglucosamine acyltransferase; PFAM: Bacterial transferase hexapeptide repeat.	0.913
lpxA	glmU	Metme_2639	Metme_4503	Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.846
lpxA	lpxD	Metme_2639	Metme_2562	Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.	0.884
lpxD	AEG02315.1	Metme_2562	Metme_3961	UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.	TIGRFAM: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; KEGG: mca:MCA0397 UDP-N-acetylglucosamine acyltransferase; PFAM: Bacterial transferase hexapeptide repeat.	0.837
lpxD	lpxA	Metme_2562	Metme_2639	UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.	Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.884