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guaA_2 guaA_2 apt apt hpt hpt guaB guaB guaA_3 guaA_3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
guaA_2GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. (518 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa)
hptHypoxanthine phosphoribosyltransferase. (184 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa)
guaA_3GMP synthase [glutamine-hydrolyzing]. (254 aa)
Your Current Organism:
Amantichitinum ursilacus
NCBI taxonomy Id: 857265
Other names: A. ursilacus, Amantichitinum ursilacus Moss et al. 2013, CIP 110167, DSM 23761, Neisseriaceae bacterium IGB-41, strain IGB-41
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