STRINGSTRING
KPC52037.1 KPC52037.1 surE surE cpdB cpdB algC_1 algC_1 ihfA ihfA KPC54602.1 KPC54602.1 guaA_1 guaA_1 cpdA cpdA KPC54782.1 KPC54782.1 ppnP ppnP yhcR yhcR KPC53984.1 KPC53984.1 purN purN purM purM dgt dgt cyaA_1 cyaA_1 nudK_1 nudK_1 cdhC_1 cdhC_1 hcrB_1 hcrB_1 tqsA tqsA pyk pyk nudK_2 nudK_2 cyaA_2 cyaA_2 hupB hupB gmk gmk spoT spoT rph rph rdgB rdgB rpfG_3 rpfG_3 guaA_2 guaA_2 pgm pgm nudF nudF purD purD purH purH purL purL KPC53385.1 KPC53385.1 hcrB_2 hcrB_2 coxS coxS nrdR nrdR tilS tilS KPC52964.1 KPC52964.1 etfB etfB apt apt hpt hpt nrdA nrdA KPC52570.1 KPC52570.1 nrdB nrdB guaB guaB ndk ndk purA purA purT purT yjmC yjmC ihfB ihfB truA truA purF purF tlyC_1 tlyC_1 KPC52071.1 KPC52071.1 adoK adoK KPC52161.1 KPC52161.1 ychF ychF deoB deoB purC purC purK purK purE purE cysD cysD cysN cysN KPC52272.1 KPC52272.1 nrdD nrdD clcB clcB KPC51948.1 KPC51948.1 algC_2 algC_2 pgdA pgdA KPC51728.1 KPC51728.1 allA allA alc alc gppA gppA KPC51527.1 KPC51527.1 KPC50499.1 KPC50499.1 KPC50531.1 KPC50531.1 KPC50538.1 KPC50538.1 rpfG_9 rpfG_9 arcC1 arcC1 relA relA pykA pykA KPC50151.1 KPC50151.1 yvdD yvdD cdhC_2 cdhC_2 hcrB_3 hcrB_3 KPC49688.1 KPC49688.1 guaA_3 guaA_3 prs prs ymdB ymdB corC corC ttcA ttcA KPC49440.1 KPC49440.1 KPC49079.1 KPC49079.1 KPC49151.1 KPC49151.1 adk adk purB purB apaH apaH
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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KPC52037.1Putative lysine decarboxylase; Belongs to the LOG family. (245 aa)
surE5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (247 aa)
cpdB2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. (700 aa)
algC_1Phosphomannomutase/phosphoglucomutase. (454 aa)
ihfAIntegration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (105 aa)
KPC54602.1Putative glutathione-dependent formaldehyde-activating enzyme. (133 aa)
guaA_1GMP synthase [glutamine-hydrolyzing]. (240 aa)
cpdA3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA. (294 aa)
KPC54782.1CHAD domain protein. (270 aa)
ppnPHypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (104 aa)
yhcREndonuclease YhcR precursor; Belongs to the 5'-nucleotidase family. (596 aa)
KPC53984.1HIT-like protein. (118 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (201 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (347 aa)
dgtDeoxyguanosinetriphosphate triphosphohydrolase. (440 aa)
cyaA_1Adenylate cyclase 1. (734 aa)
nudK_1GDP-mannose pyrophosphatase NudK. (199 aa)
cdhC_1Caffeine dehydrogenase subunit gamma. (168 aa)
hcrB_14-hydroxybenzoyl-CoA reductase subunit beta. (329 aa)
tqsAAI-2 transport protein TqsA. (630 aa)
pykPyruvate kinase. (583 aa)
nudK_2GDP-mannose pyrophosphatase NudK. (194 aa)
cyaA_2Adenylate cyclase 1. (620 aa)
hupBDNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa)
spoTBifunctional (p)ppGpp synthase/hydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (733 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
rdgBdITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
rpfG_3Cyclic di-GMP phosphodiesterase response regulator RpfG. (491 aa)
guaA_2GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. (518 aa)
pgmPhosphoglucomutase. (542 aa)
nudFADP-ribose pyrophosphatase. (189 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (429 aa)
purHBifunctional purine biosynthesis protein PurH. (520 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1315 aa)
KPC53385.1Hypothetical protein; Belongs to the UPF0301 (AlgH) family. (183 aa)
hcrB_24-hydroxybenzoyl-CoA reductase subunit beta. (325 aa)
coxSCarbon monoxide dehydrogenase small chain. (228 aa)
nrdRTranscriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (150 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (458 aa)
KPC52964.1Hypothetical protein. (196 aa)
etfBElectron transfer flavoprotein subunit beta. (252 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa)
hptHypoxanthine phosphoribosyltransferase. (184 aa)
nrdARibonucleoside-diphosphate reductase 1 subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (972 aa)
KPC52570.1Pheromone autoinducer 2 transporter. (393 aa)
nrdBRibonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (363 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (404 aa)
yjmCPutative oxidoreductase YjmC; Belongs to the LDH2/MDH2 oxidoreductase family. (356 aa)
ihfBIntegration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (94 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (260 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (510 aa)
tlyC_1Hemolysin C. (437 aa)
KPC52071.1DegV domain-containing protein. (315 aa)
adoKAdenosine kinase. (313 aa)
KPC52161.1CYTH domain protein. (156 aa)
ychFRibosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (408 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (293 aa)
purKN5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (379 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa)
cysDSulfate adenylyltransferase subunit 2. (308 aa)
cysNSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (483 aa)
KPC52272.1Anaerobic ribonucleoside triphosphate reductase. (57 aa)
nrdDAnaerobic ribonucleoside-triphosphate reductase. (582 aa)
clcBVoltage-gated ClC-type chloride channel ClcB. (196 aa)
KPC51948.1Transcriptional regulator BolA; Belongs to the BolA/IbaG family. (88 aa)
algC_2Phosphomannomutase/phosphoglucomutase. (455 aa)
pgdAPeptidoglycan deacetylase. (309 aa)
KPC51728.1Asp/Glu/Hydantoin racemase. (243 aa)
allAUreidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (167 aa)
alcAllantoicase; Belongs to the allantoicase family. (335 aa)
gppAGuanosine-5'-triphosphate,3'-diphosphate pyrophosphatase. (493 aa)
KPC51527.1Hypothetical protein. (110 aa)
KPC50499.1Hypothetical protein. (362 aa)
KPC50531.1Hypothetical protein. (126 aa)
KPC50538.1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (341 aa)
rpfG_9Cyclic di-GMP phosphodiesterase response regulator RpfG. (455 aa)
arcC1Carbamate kinase 1; Belongs to the carbamate kinase family. (319 aa)
relAGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (732 aa)
pykAPyruvate kinase II; Belongs to the pyruvate kinase family. (478 aa)
KPC50151.15'-nucleotidase. (313 aa)
yvdDLOG family protein YvdD; Belongs to the LOG family. (195 aa)
cdhC_2Caffeine dehydrogenase subunit gamma. (192 aa)
hcrB_34-hydroxybenzoyl-CoA reductase subunit beta. (351 aa)
KPC49688.1Putative inner membrane protein. (408 aa)
guaA_3GMP synthase [glutamine-hydrolyzing]. (254 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
ymdBO-acetyl-ADP-ribose deacetylase. (174 aa)
corCMagnesium and cobalt efflux protein CorC. (288 aa)
ttcAtRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (314 aa)
KPC49440.1LysM domain/BON superfamily protein. (354 aa)
KPC49079.1Glutathione-dependent formaldehyde-activating enzyme. (163 aa)
KPC49151.1AP-4-A phosphorylase. (138 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa)
purBAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa)
apaHBis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (274 aa)
Your Current Organism:
Amantichitinum ursilacus
NCBI taxonomy Id: 857265
Other names: A. ursilacus, Amantichitinum ursilacus Moss et al. 2013, CIP 110167, DSM 23761, Neisseriaceae bacterium IGB-41, strain IGB-41
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