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pck pck CVAR_0553 CVAR_0553 cat1 cat1 cat2 cat2 gltA gltA purU purU mdh mdh gabD3 gabD3 gabD6 gabD6 gabD5 gabD5 ppc ppc mqo mqo fum fum CVAR_1945 CVAR_1945 sdhB sdhB sdhA sdhA CVAR_2763 CVAR_2763 gabD4 gabD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pckPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (612 aa)
CVAR_0553Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa)
cat1succinyl-CoA:Coenzyme A transferase; Acetyl-CoA hydrolase. (500 aa)
cat2succinyl-CoA:Coenzyme A transferase; Acetyl-CoA hydrolase. (500 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (431 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (297 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (336 aa)
gabD3NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (464 aa)
gabD6NAD-dependent aldehyde dehydrogenases. (463 aa)
gabD5NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (492 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (946 aa)
mqoMalate:quinone oxidoreductase; Predicted dehydrogenase. (492 aa)
fumFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (469 aa)
CVAR_1945Hypothetical protein; NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (527 aa)
sdhBSuccinate dehydrogenase/fumarate reductase, Fe- S protein subunit. (249 aa)
sdhASuccinate dehydrogenase/fumarate reductase, flavoprotein subunit. (677 aa)
CVAR_2763Succinate dehydrogenase subunit. (246 aa)
gabD4NAD-dependent aldehyde dehydrogenases. (474 aa)
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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