STRINGSTRING
CVAR_3060 CVAR_3060 fadA5 fadA5 sucB sucB lipB lipB CVAR_1110 CVAR_1110 fadA2 fadA2 phdC phdC pcaL pcaL pcaF pcaF pcaD pcaD CVAR_0799 CVAR_0799 CVAR_0798 CVAR_0798 CVAR_0770 CVAR_0770 CVAR_0745 CVAR_0745 prpC prpC mshD mshD cysE cysE CVAR_0626 CVAR_0626 gltA gltA CVAR_0060 CVAR_0060 CVAR_0092 CVAR_0092 CVAR_0101 CVAR_0101 maa maa CVAR_0175 CVAR_0175 cmtB cmtB CVAR_0214 CVAR_0214 cmtC cmtC pks13 pks13 CVAR_0261 CVAR_0261 fadA1 fadA1 CVAR_0311 CVAR_0311 CVAR_0406 CVAR_0406 CVAR_0427 CVAR_0427 pta pta CVAR_0465 CVAR_0465 CVAR_0481 CVAR_0481 CVAR_0497 CVAR_0497 lsr2A lsr2A lsr2B lsr2B aceB aceB CVAR_2564 CVAR_2564 CVAR_2552 CVAR_2552 fas fas leuA leuA CVAR_2406 CVAR_2406 gcp gcp metX metX CVAR_2214 CVAR_2214 fadA4 fadA4 CVAR_2066 CVAR_2066 CVAR_2034 CVAR_2034 glmU glmU mvaS mvaS CVAR_1928 CVAR_1928 CVAR_1886 CVAR_1886 dapD dapD sucA sucA CVAR_1769 CVAR_1769 CVAR_1727 CVAR_1727 CVAR_1556 CVAR_1556 lnt lnt CVAR_1331 CVAR_1331 argJ argJ CVAR_1238 CVAR_1238 fadA3 fadA3 CVAR_1232 CVAR_1232 CVAR_1150 CVAR_1150 CVAR_1143 CVAR_1143 CVAR_1141 CVAR_1141
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CVAR_3060Hypothetical protein. (226 aa)
fadA5Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
sucBPyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (563 aa)
lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (250 aa)
CVAR_1110Predicted acetyltransferase. (189 aa)
fadA2Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
phdCPyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (469 aa)
pcaL3-oxoadipate enol-lactonase; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (408 aa)
pcaFAcetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
pcaD3-oxoadipate enol-lactonase; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (96 aa)
CVAR_0799Histone acetyltransferase HPA2 and related acetyltransferases. (224 aa)
CVAR_0798Predicted membrane protein. (388 aa)
CVAR_0770Hypothetical protein. (363 aa)
CVAR_0745Uncharacterized protein conserved in bacteria. (397 aa)
prpCCitrate synthase; Belongs to the citrate synthase family. (384 aa)
mshDMshD acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. (330 aa)
cysESerine acetyltransferase. (194 aa)
CVAR_0626Putative secreted protein; Glutamine cyclotransferase. (519 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (431 aa)
CVAR_0060GCN5-related N-acetyltransferase; Histone acetyltransferase HPA2 and related acetyltransferases. (186 aa)
CVAR_0092Acetyltransferases, including N-acetylases of ribosomal proteins. (175 aa)
CVAR_0101Putative membrane protein; Predicted acyltransferases. (856 aa)
maaMaltose O-acetyltransferase; Acetyltransferase (isoleucine patch superfamily). (206 aa)
CVAR_0175Putative membrane protein; Predicted acyltransferases. (865 aa)
cmtBTrehalose corynomycolyl transferase; Predicted esterase. (332 aa)
CVAR_0214Hypothetical protein; 1-acyl-sn-glycerol-3-phosphate acyltransferase. (308 aa)
cmtCTrehalose corynomycolyl transferase; Predicted esterase. (364 aa)
pks13Polyketide synthase modules and related proteins. (1642 aa)
CVAR_0261Predicted integral membrane protein. (364 aa)
fadA1Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
CVAR_0311Serine acetyltransferase. (184 aa)
CVAR_0406Hypothetical protein; Predicted acyltransferase. (200 aa)
CVAR_0427Hypothetical protein; Histone acetyltransferase HPA2 and related acetyltransferases. (167 aa)
ptaPhosphate acetyltransferase; Phosphotransacetylase. (477 aa)
CVAR_0465Hypothetical protein; Histone acetyltransferase HPA2 and related acetyltransferases. (371 aa)
CVAR_0481Histone acetyltransferase HPA2 and related acetyltransferases. (113 aa)
CVAR_0497Hypothetical protein; Acetyltransferases, including N-acetylases of ribosomal proteins. (187 aa)
lsr2AMultifunctional histone-like protein. (120 aa)
lsr2BMultifunctional histone-like protein. (120 aa)
aceBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (734 aa)
CVAR_2564Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (294 aa)
CVAR_2552Putative membrane protein; Predicted acyltransferases. (670 aa)
fasFatty acid synthase; Enoyl reductase domain of yeast-type FAS1. (3144 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (639 aa)
CVAR_24068-amino-7-oxononanoate synthase; 7-keto-8-aminopelargonate synthetase and related enzymes. (375 aa)
gcpO-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (784 aa)
metXHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (373 aa)
CVAR_2214Putative membrane protein. (619 aa)
fadA4Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
CVAR_2066Hypothetical protein; Acetyltransferases, including N-acetylases of ribosomal proteins. (212 aa)
CVAR_2034Putative membrane protein. (295 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (480 aa)
mvaS3-hydroxy-3-methylglutaryl CoA synthase. (395 aa)
CVAR_1928Hypothetical protein; Sortase and related acyltransferases. (195 aa)
CVAR_1886Hypothetical protein; 1-acyl-sn-glycerol-3-phosphate acyltransferase. (195 aa)
dapD2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (303 aa)
sucA2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (1245 aa)
CVAR_1769Hypothetical protein; Acetyltransferases, including N-acetylases of ribosomal proteins. (197 aa)
CVAR_1727Histone acetyltransferase HPA2 and related acetyltransferases. (185 aa)
CVAR_1556Hypothetical protein; Lauroyl/myristoyl acyltransferase. (309 aa)
lntPolyprenol-phosphate-mannose synthase domain 2; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (465 aa)
CVAR_1331Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (352 aa)
argJN-acetylglutamate- acetylornithineacetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (392 aa)
CVAR_1238Putative secreted protein; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (539 aa)
fadA3Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (438 aa)
CVAR_1232Hypothetical protein; Acyl dehydratase. (309 aa)
CVAR_1150Hypothetical protein; Acetyltransferases. (205 aa)
CVAR_1143Predicted membrane protein. (376 aa)
CVAR_11411-acyl-sn-glycerol-3-phosphate acyltransferase. (247 aa)
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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