STRINGSTRING
CVAR_1155 CVAR_1155 ftsI ftsI murE murE murF murF mraY mraY parA parA murB murB CVAR_2318 CVAR_2318 CVAR_2306 CVAR_2306 CVAR_2007 CVAR_2007 CVAR_1735 CVAR_1735 xerC xerC ftsK ftsK whiA whiA CVAR_1279 CVAR_1279 CVAR_1276 CVAR_1276 CVAR_1169 CVAR_1169 CVAR_1168 CVAR_1168 ftsW ftsW murD murD sepF sepF ftsZ ftsZ ftsQ ftsQ murC murC murG murG crgA crgA CVAR_0063 CVAR_0063 rodA rodA CVAR_0066 CVAR_0066 CVAR_0473 CVAR_0473 murA murA ftsE ftsE ftsX ftsX tig tig
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CVAR_1155Hypothetical protein. (238 aa)
ftsICell division protein FtsI/penicillin-binding protein 2. (640 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (547 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (480 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (366 aa)
parAATPases involved in chromosome partitioning. (314 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (394 aa)
CVAR_2318Hypothetical protein; DNA segregation ATPase FtsK/SpoIIIE and related proteins. (485 aa)
CVAR_2306Hypothetical protein; DNA segregation ATPase FtsK/SpoIIIE and related proteins. (639 aa)
CVAR_2007Putative secreted protein; Septum formation initiator. (193 aa)
CVAR_1735Cell division initiation protein. (258 aa)
xerCTyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (327 aa)
ftsKCell division protein; DNA segregation ATPase FtsK/SpoIIIE and related proteins. (1114 aa)
whiAPutative WhiA transcription regulator; Involved in cell division and chromosome segregation. (318 aa)
CVAR_1279Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (181 aa)
CVAR_1276Site-specific recombinase XerD. (226 aa)
CVAR_1169Cell division initiation protein. (352 aa)
CVAR_1168Hypothetical protein. (99 aa)
ftsWBacterial cell division membrane protein; Belongs to the SEDS family. (509 aa)
murDUDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (473 aa)
sepFCell division protein. (199 aa)
ftsZCell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (426 aa)
ftsQCell division protein; Essential cell division protein. (231 aa)
murCUDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (499 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (370 aa)
crgAHypothetical protein; Involved in cell division; Belongs to the CrgA family. (89 aa)
CVAR_0063Cell division protein FtsI/penicillin-binding protein 2. (470 aa)
rodABacterial cell division membrane protein; Belongs to the SEDS family. (463 aa)
CVAR_0066Putative secreted protein; FOG: FHA domain. (164 aa)
CVAR_0473Hypothetical protein; Acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase and related deacylases. (466 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
ftsECell division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division. (229 aa)
ftsXCell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (300 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (452 aa)
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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