node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CVAR_0553 | aceE | CVAR_0553 | CVAR_1084 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.924 |
CVAR_0553 | cat1 | CVAR_0553 | CVAR_0586 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | succinyl-CoA:Coenzyme A transferase; Acetyl-CoA hydrolase. | 0.525 |
CVAR_0553 | cat2 | CVAR_0553 | CVAR_0587 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | succinyl-CoA:Coenzyme A transferase; Acetyl-CoA hydrolase. | 0.525 |
CVAR_0553 | fum | CVAR_0553 | CVAR_1922 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.426 |
CVAR_0553 | gltA | CVAR_0553 | CVAR_0632 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Citrate synthase; Belongs to the citrate synthase family. | 0.977 |
CVAR_0553 | icd | CVAR_0553 | CVAR_2249 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. | 0.422 |
CVAR_0553 | mdh | CVAR_0553 | CVAR_0899 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.961 |
CVAR_0553 | mqo | CVAR_0553 | CVAR_1651 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate:quinone oxidoreductase; Predicted dehydrogenase. | 0.930 |
CVAR_0553 | pck | CVAR_0553 | CVAR_0267 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.968 |
CVAR_0553 | pdhA | CVAR_0553 | CVAR_0936 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.912 |
CVAR_0553 | pdhB | CVAR_0553 | CVAR_0937 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. | 0.923 |
CVAR_0553 | phdC | CVAR_0553 | CVAR_0938 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.824 |
CVAR_2763 | cat1 | CVAR_2763 | CVAR_0586 | Succinate dehydrogenase subunit. | succinyl-CoA:Coenzyme A transferase; Acetyl-CoA hydrolase. | 0.900 |
CVAR_2763 | cat2 | CVAR_2763 | CVAR_0587 | Succinate dehydrogenase subunit. | succinyl-CoA:Coenzyme A transferase; Acetyl-CoA hydrolase. | 0.900 |
CVAR_2763 | fum | CVAR_2763 | CVAR_1922 | Succinate dehydrogenase subunit. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.900 |
CVAR_2763 | sdhA | CVAR_2763 | CVAR_2762 | Succinate dehydrogenase subunit. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.999 |
CVAR_2763 | sdhB | CVAR_2763 | CVAR_2761 | Succinate dehydrogenase subunit. | Succinate dehydrogenase/fumarate reductase, Fe- S protein subunit. | 0.998 |
aceE | CVAR_0553 | CVAR_1084 | CVAR_0553 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.924 |
aceE | gltA | CVAR_1084 | CVAR_0632 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Citrate synthase; Belongs to the citrate synthase family. | 0.451 |
aceE | lpd | CVAR_1084 | CVAR_2769 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.982 |