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pck pck CVAR_0553 CVAR_0553 cat1 cat1 cat2 cat2 gltA gltA mdh mdh pdhA pdhA pdhB pdhB phdC phdC phdD phdD aceE aceE sucB sucB acn acn mqo mqo fum fum icd icd sdhB sdhB sdhA sdhA CVAR_2763 CVAR_2763 lpd lpd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pckPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (612 aa)
CVAR_0553Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa)
cat1succinyl-CoA:Coenzyme A transferase; Acetyl-CoA hydrolase. (500 aa)
cat2succinyl-CoA:Coenzyme A transferase; Acetyl-CoA hydrolase. (500 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (431 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (336 aa)
pdhAPyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (376 aa)
pdhBPyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (325 aa)
phdCPyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (469 aa)
phdDPyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (476 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (927 aa)
sucBPyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (563 aa)
acnAconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (937 aa)
mqoMalate:quinone oxidoreductase; Predicted dehydrogenase. (492 aa)
fumFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (469 aa)
icdMonomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (746 aa)
sdhBSuccinate dehydrogenase/fumarate reductase, Fe- S protein subunit. (249 aa)
sdhASuccinate dehydrogenase/fumarate reductase, flavoprotein subunit. (677 aa)
CVAR_2763Succinate dehydrogenase subunit. (246 aa)
lpdPyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (474 aa)
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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