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fadA1 fadA1 pcaF pcaF mvaK1 mvaK1 mvaD mvaD mvaK2 mvaK2 idi idi fadA2 fadA2 CVAR_1064 CVAR_1064 idsA idsA fadA3 fadA3 dxs dxs dxr dxr CVAR_1939 CVAR_1939 mvaA mvaA mvaS mvaS ispE ispE fadA4 fadA4 ispB ispB fadA5 fadA5
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fadA1Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
pcaFAcetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
mvaK1Mevalonate kinase. (404 aa)
mvaDMevalonate pyrophosphate decarboxylase. (309 aa)
mvaK2Mevalonate kinase. (358 aa)
idiIsopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (377 aa)
fadA2Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
CVAR_1064Hypothetical protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (245 aa)
idsAGeranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (373 aa)
fadA3Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (438 aa)
dxs1-deoxyxylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (625 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (394 aa)
CVAR_1939Hypothetical protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (237 aa)
mvaAHydroxymethylglutaryl-CoA reductase. (335 aa)
mvaS3-hydroxy-3-methylglutaryl CoA synthase. (395 aa)
ispE4-diphosphocytidyl-2-C-methyl-D- erythritolkinase; 4-diphosphocytidyl-2C-methyl-D-erythritol 2- phosphate synthase. (349 aa)
fadA4Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
ispBGeranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (338 aa)
fadA5Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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