STRINGSTRING
H6BJU0_EXODN H6BJU0_EXODN H6BJZ8_EXODN H6BJZ8_EXODN H6BLG1_EXODN H6BLG1_EXODN H6BLG4_EXODN H6BLG4_EXODN H6BMF0_EXODN H6BMF0_EXODN H6BN43_EXODN H6BN43_EXODN H6BNN6_EXODN H6BNN6_EXODN H6BPJ2_EXODN H6BPJ2_EXODN H6BPK7_EXODN H6BPK7_EXODN H6BPP7_EXODN H6BPP7_EXODN H6BQQ7_EXODN H6BQQ7_EXODN H6BQQ8_EXODN H6BQQ8_EXODN H6BRH8_EXODN H6BRH8_EXODN H6BRS1_EXODN H6BRS1_EXODN H6BS49_EXODN H6BS49_EXODN H6BSF8_EXODN H6BSF8_EXODN H6BSZ3_EXODN H6BSZ3_EXODN H6BTR6_EXODN H6BTR6_EXODN H6BTS1_EXODN H6BTS1_EXODN H6BUK4_EXODN H6BUK4_EXODN H6BVE5_EXODN H6BVE5_EXODN H6BVN0_EXODN H6BVN0_EXODN H6BWV1_EXODN H6BWV1_EXODN H6BXW5_EXODN H6BXW5_EXODN H6BXW9_EXODN H6BXW9_EXODN H6BZG5_EXODN H6BZG5_EXODN H6C0A7_EXODN H6C0A7_EXODN H6C0F5_EXODN H6C0F5_EXODN SLX4 SLX4 H6C0Y8_EXODN H6C0Y8_EXODN H6C1C2_EXODN H6C1C2_EXODN H6C1H4_EXODN H6C1H4_EXODN H6C1H5_EXODN H6C1H5_EXODN H6C1J6_EXODN H6C1J6_EXODN H6C2R9_EXODN H6C2R9_EXODN H6C2X1_EXODN H6C2X1_EXODN H6C336_EXODN H6C336_EXODN H6C3K7_EXODN H6C3K7_EXODN H6C5I5_EXODN H6C5I5_EXODN H6C5J9_EXODN H6C5J9_EXODN H6C729_EXODN H6C729_EXODN H6C7H5_EXODN H6C7H5_EXODN H6C7V9_EXODN H6C7V9_EXODN H6C7Z0_EXODN H6C7Z0_EXODN H6C8V5_EXODN H6C8V5_EXODN H6C9K6_EXODN H6C9K6_EXODN H6C9P0_EXODN H6C9P0_EXODN H6C9S3_EXODN H6C9S3_EXODN H6C9T8_EXODN H6C9T8_EXODN H6CAJ9_EXODN H6CAJ9_EXODN H6CAL0_EXODN H6CAL0_EXODN H6CAL1_EXODN H6CAL1_EXODN PAC1-2 PAC1-2 H6CAY6_EXODN H6CAY6_EXODN H6CBE6_EXODN H6CBE6_EXODN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H6BJU0_EXODNNuclear movement protein nudC. (195 aa)
H6BJZ8_EXODNRRN9 domain-containing protein. (818 aa)
H6BLG1_EXODNActin-like protein 3; Belongs to the actin family. (439 aa)
H6BLG4_EXODNDNA ligase (ATP). (867 aa)
H6BMF0_EXODNActin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
H6BN43_EXODNActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (368 aa)
H6BNN6_EXODNADF-H domain-containing protein. (141 aa)
H6BPJ2_EXODNDynactin 5. (221 aa)
H6BPK7_EXODNUncharacterized protein. (424 aa)
H6BPP7_EXODNUncharacterized protein. (529 aa)
H6BQQ7_EXODNActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (196 aa)
H6BQQ8_EXODNDynactin 4. (584 aa)
H6BRH8_EXODNUncharacterized protein. (815 aa)
H6BRS1_EXODNDynein heavy chain, cytoplasmic. (4347 aa)
H6BS49_EXODNDUF4045 domain-containing protein. (1679 aa)
H6BSF8_EXODNActin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (188 aa)
H6BSZ3_EXODNUncharacterized protein. (889 aa)
H6BTR6_EXODNADA HAT complex component 1. (322 aa)
H6BTS1_EXODNWH2 domain-containing protein. (498 aa)
H6BUK4_EXODNCofilin; Belongs to the actin-binding proteins ADF family. (152 aa)
H6BVE5_EXODNZn(2)-C6 fungal-type domain-containing protein. (581 aa)
H6BVN0_EXODNUncharacterized protein. (388 aa)
H6BWV1_EXODNF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (274 aa)
H6BXW5_EXODNUncharacterized protein. (264 aa)
H6BXW9_EXODNUncharacterized protein. (1210 aa)
H6BZG5_EXODNProtein hob3. (261 aa)
H6C0A7_EXODNUncharacterized protein. (776 aa)
H6C0F5_EXODNActin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (1021 aa)
H6C0Y8_EXODNWiskott-Aldrich syndrome protein. (633 aa)
H6C1C2_EXODNUncharacterized protein. (362 aa)
H6C1H4_EXODNDynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (98 aa)
H6C1H5_EXODNUncharacterized protein. (118 aa)
H6C1J6_EXODNDUF2013 domain-containing protein. (876 aa)
H6C2R9_EXODNActin-like protein; Belongs to the actin family. (382 aa)
H6C2X1_EXODNDynactin 1. (1397 aa)
H6C336_EXODNUncharacterized protein. (254 aa)
H6C3K7_EXODNPTK9 protein tyrosine kinase 9. (384 aa)
H6C5I5_EXODNUncharacterized protein. (1168 aa)
H6C5J9_EXODNUncharacterized protein. (452 aa)
H6C729_EXODNUncharacterized protein. (616 aa)
H6C7H5_EXODNMyosin I; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1286 aa)
H6C7V9_EXODNDynein intermediate chain, cytosolic. (691 aa)
H6C7Z0_EXODNDynein light intermediate chain 1, cytosolic. (655 aa)
H6C8V5_EXODNActin like protein 2/3 complex, subunit 2. (404 aa)
H6C9K6_EXODNFimbrin. (652 aa)
H6C9P0_EXODNAdenylyl cyclase-associated protein; Belongs to the CAP family. (528 aa)
H6C9S3_EXODNSH3 domain-containing protein. (406 aa)
H6C9T8_EXODNNUDE_C domain-containing protein. (622 aa)
H6CAJ9_EXODNWD_REPEATS_REGION domain-containing protein. (626 aa)
H6CAL0_EXODNF-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (282 aa)
H6CAL1_EXODNUncharacterized protein. (665 aa)
PAC1-2Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (454 aa)
H6CAY6_EXODNProtein-tyrosine kinase. (732 aa)
H6CBE6_EXODNUncharacterized protein. (351 aa)
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
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