56 items (Exophiala dermatitidis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	H6BL25_EXODN	Spindle pole body component. (770 aa)
	H6BLE4_EXODN	TFCD_C domain-containing protein. (1194 aa)
	H6BLP1_EXODN	Uncharacterized protein. (468 aa)
	H6BLU7_EXODN	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1262 aa)
	H6BMX0_EXODN	Uncharacterized protein. (936 aa)
	H6BNW0_EXODN	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (985 aa)
	H6BPT9_EXODN	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	H6BQJ5_EXODN	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (777 aa)
	H6BQM3_EXODN	Ser/Thr protein kinase MPS1 (Regulatory cell proliferation kinase 1). (871 aa)
	H6BQN0_EXODN	RP/EB family microtubule-associated protein. (261 aa)
	H6BQT9_EXODN	Dynactin 2. (535 aa)
	H6BRH2_EXODN	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
	H6BRS1_EXODN	Dynein heavy chain, cytoplasmic. (4347 aa)
	H6BSY6_EXODN	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (455 aa)
	H6BSZ2_EXODN	Cell division cycle 14. (657 aa)
	H6BTG8_EXODN	Uncharacterized protein. (524 aa)
	H6BUW1_EXODN	Spindle pole body component. (965 aa)
	H6BVZ4_EXODN	CAP-Gly domain-containing protein. (757 aa)
	H6BWB0_EXODN	Uncharacterized protein. (2335 aa)
	H6BX80_EXODN	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	H6BXA5_EXODN	AIP3 domain-containing protein. (1134 aa)
	H6BYP7_EXODN	PH domain-containing protein. (1604 aa)
	H6BYZ8_EXODN	Kinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1028 aa)
	H6BZV4_EXODN	Uncharacterized protein. (553 aa)
	H6C073_EXODN	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (480 aa)
	H6C0H8_EXODN	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (861 aa)
	H6C1H4_EXODN	Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (98 aa)
	H6C1I4_EXODN	Uncharacterized protein. (1275 aa)
	H6C271_EXODN	DNA-repair protein XRCC2. (507 aa)
	H6C2D6_EXODN	Cell division cycle protein 37. (531 aa)
	H6C2G7_EXODN	Aurora kinase, other; Belongs to the protein kinase superfamily. (413 aa)
	H6C2X1_EXODN	Dynactin 1. (1397 aa)
	H6C364_EXODN	Centrin-2. (236 aa)
	H6C3B7_EXODN	Uncharacterized protein. (542 aa)
	H6C3W3_EXODN	Spindle pole body component. (945 aa)
	H6C417_EXODN	Vesicle-fusing ATPase. (476 aa)
	H6C4S6_EXODN	Uncharacterized protein. (949 aa)
	PAC1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (432 aa)
	H6C4X0_EXODN	Uncharacterized protein. (324 aa)
	H6C626_EXODN	Spindle pole body component. (937 aa)
	H6C662_EXODN	CAP-Gly domain-containing protein. (854 aa)
	H6C6G4_EXODN	Uncharacterized protein. (610 aa)
	H6C6K5_EXODN	Cell division control protein 48; Belongs to the AAA ATPase family. (821 aa)
	H6C7H2_EXODN	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	H6C7H7_EXODN	Serine/threonine-protein kinase. (1054 aa)
	H6C7Z0_EXODN	Dynein light intermediate chain 1, cytosolic. (655 aa)
	H6C8F1_EXODN	Uncharacterized protein. (633 aa)
	H6C8W3_EXODN	Uncharacterized protein. (270 aa)
	H6C9T8_EXODN	NUDE_C domain-containing protein. (622 aa)
	H6CAM0_EXODN	AAA family ATPase. (673 aa)
	PAC1-2	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (454 aa)
	H6CB52_EXODN	Uncharacterized protein. (400 aa)
	H6CBK7_EXODN	Calponin-homology (CH) domain-containing protein. (1150 aa)
	H6CBN4_EXODN	Uncharacterized protein. (422 aa)
	H6BM06_EXODN	Uncharacterized protein. (725 aa)
	H6CC15_EXODN	Adenosinetriphosphatase. (270 aa)

Your Current Organism:

Exophiala dermatitidis

NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H6BL25_EXODN	H6BSY6_EXODN	H6BL25	H6BSY6	Spindle pole body component.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.990
H6BL25_EXODN	H6BUW1_EXODN	H6BL25	H6BUW1	Spindle pole body component.	Spindle pole body component.	0.996
H6BL25_EXODN	H6C3W3_EXODN	H6BL25	H6C3W3	Spindle pole body component.	Spindle pole body component.	0.994
H6BL25_EXODN	H6C626_EXODN	H6BL25	H6C626	Spindle pole body component.	Spindle pole body component.	0.991
H6BL25_EXODN	H6CBN4_EXODN	H6BL25	H6CBN4	Spindle pole body component.	Uncharacterized protein.	0.942
H6BLE4_EXODN	H6BM06_EXODN	H6BLE4	H6BM06	TFCD_C domain-containing protein.	Uncharacterized protein.	0.501
H6BLE4_EXODN	H6BNW0_EXODN	H6BLE4	H6BNW0	TFCD_C domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.573
H6BLE4_EXODN	H6BPT9_EXODN	H6BLE4	H6BPT9	TFCD_C domain-containing protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.433
H6BLE4_EXODN	H6BVZ4_EXODN	H6BLE4	H6BVZ4	TFCD_C domain-containing protein.	CAP-Gly domain-containing protein.	0.913
H6BLE4_EXODN	H6BX80_EXODN	H6BLE4	H6BX80	TFCD_C domain-containing protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.571
H6BLE4_EXODN	H6C662_EXODN	H6BLE4	H6C662	TFCD_C domain-containing protein.	CAP-Gly domain-containing protein.	0.530
H6BLE4_EXODN	H6C7H2_EXODN	H6BLE4	H6C7H2	TFCD_C domain-containing protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.433
H6BLE4_EXODN	H6CC15_EXODN	H6BLE4	H6CC15	TFCD_C domain-containing protein.	Adenosinetriphosphatase.	0.600
H6BLP1_EXODN	H6BM06_EXODN	H6BLP1	H6BM06	Uncharacterized protein.	Uncharacterized protein.	0.501
H6BLP1_EXODN	H6BNW0_EXODN	H6BLP1	H6BNW0	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.476
H6BLP1_EXODN	H6BPT9_EXODN	H6BLP1	H6BPT9	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.433
H6BLP1_EXODN	H6BVZ4_EXODN	H6BLP1	H6BVZ4	Uncharacterized protein.	CAP-Gly domain-containing protein.	0.913
H6BLP1_EXODN	H6BX80_EXODN	H6BLP1	H6BX80	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.571
H6BLP1_EXODN	H6C662_EXODN	H6BLP1	H6C662	Uncharacterized protein.	CAP-Gly domain-containing protein.	0.530
H6BLP1_EXODN	H6C7H2_EXODN	H6BLP1	H6C7H2	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.433

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