STRINGSTRING
H6CAB5_EXODN H6CAB5_EXODN H6BJY9_EXODN H6BJY9_EXODN H6BKF9_EXODN H6BKF9_EXODN H6BLE7_EXODN H6BLE7_EXODN H6BM03_EXODN H6BM03_EXODN H6BN55_EXODN H6BN55_EXODN H6BPV8_EXODN H6BPV8_EXODN H6BRN3_EXODN H6BRN3_EXODN H6BS87_EXODN H6BS87_EXODN H6BSH4_EXODN H6BSH4_EXODN H6BVD6_EXODN H6BVD6_EXODN H6BZH3_EXODN H6BZH3_EXODN H6C3N8_EXODN H6C3N8_EXODN H6C649_EXODN H6C649_EXODN H6C693_EXODN H6C693_EXODN H6C6Q7_EXODN H6C6Q7_EXODN H6C7Z6_EXODN H6C7Z6_EXODN H6CA38_EXODN H6CA38_EXODN H6CBX4_EXODN H6CBX4_EXODN
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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H6CAB5_EXODNS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (314 aa)
H6BJY9_EXODNCAP10 domain-containing protein. (610 aa)
H6BKF9_EXODNUracil phosphoribosyltransferase. (287 aa)
H6BLE7_EXODNNicotinate phosphoribosyltransferase. (487 aa)
H6BM03_EXODNPribosyltran domain-containing protein. (203 aa)
H6BN55_EXODNATP phosphoribosyltransferase. (317 aa)
H6BPV8_EXODNThiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (331 aa)
H6BRN3_EXODNAdenine phosphoribosyltransferase. (213 aa)
H6BS87_EXODNNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (315 aa)
H6BSH4_EXODNQueuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (475 aa)
H6BVD6_EXODNAnthranilate phosphoribosyltransferase. (422 aa)
H6BZH3_EXODNPoly [ADP-ribose] polymerase. (710 aa)
H6C3N8_EXODNImidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (571 aa)
H6C649_EXODNOrotate phosphoribosyltransferase. (245 aa)
H6C693_EXODNAmidophosphoribosyltransferase. (592 aa)
H6C6Q7_EXODNCAP10 domain-containing protein. (412 aa)
H6C7Z6_EXODNInitiator tRNA phosphoribosyl transferase. (461 aa)
H6CA38_EXODNQueuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (469 aa)
H6CBX4_EXODNBRCT domain-containing protein. (505 aa)
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
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