STRINGSTRING
H6CAB5_EXODN H6CAB5_EXODN H6C9M8_EXODN H6C9M8_EXODN H6C9I7_EXODN H6C9I7_EXODN H6C834_EXODN H6C834_EXODN H6C7D0_EXODN H6C7D0_EXODN H6C6K0_EXODN H6C6K0_EXODN H6BNS5_EXODN H6BNS5_EXODN H6BK31_EXODN H6BK31_EXODN H6BK76_EXODN H6BK76_EXODN H6BKF9_EXODN H6BKF9_EXODN H6BM03_EXODN H6BM03_EXODN MRI1 MRI1 H6CB57_EXODN H6CB57_EXODN H6BYY5_EXODN H6BYY5_EXODN AAH1 AAH1 H6C150_EXODN H6C150_EXODN H6C193_EXODN H6C193_EXODN H6BYD4_EXODN H6BYD4_EXODN MDE1 MDE1 H6BRN3_EXODN H6BRN3_EXODN H6BR46_EXODN H6BR46_EXODN ADI1 ADI1 H6BNZ4_EXODN H6BNZ4_EXODN H6BNU4_EXODN H6BNU4_EXODN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H6CAB5_EXODNS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (314 aa)
H6C9M8_EXODNUncharacterized protein. (132 aa)
H6C9I7_EXODNRED_N domain-containing protein. (516 aa)
H6C834_EXODNCytosine deaminase. (150 aa)
H6C7D0_EXODNAMP deaminase. (1146 aa)
H6C6K0_EXODNUridine kinase; Belongs to the uridine kinase family. (478 aa)
H6BNS5_EXODNIMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (389 aa)
H6BK31_EXODNUncharacterized protein. (829 aa)
H6BK76_EXODNDNA glycosylase. (365 aa)
H6BKF9_EXODNUracil phosphoribosyltransferase. (287 aa)
H6BM03_EXODNPribosyltran domain-containing protein. (203 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (396 aa)
H6CB57_EXODNPyridoxal kinase. (375 aa)
H6BYY5_EXODNAdenosine kinase. (348 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (348 aa)
H6C150_EXODNIsochorismatase family hydrolase. (232 aa)
H6C193_EXODNPyridox_oxase_2 domain-containing protein. (289 aa)
H6BYD4_EXODNUracil phosphoribosyltransferase. (248 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (236 aa)
H6BRN3_EXODNAdenine phosphoribosyltransferase. (213 aa)
H6BR46_EXODNCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (162 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (274 aa)
H6BNZ4_EXODNNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (447 aa)
H6BNU4_EXODNCMP/dCMP-type deaminase domain-containing protein. (345 aa)
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.