STRINGSTRING
H6C662_EXODN H6C662_EXODN H6C6G0_EXODN H6C6G0_EXODN TIF6 TIF6 H6C6P8_EXODN H6C6P8_EXODN H6C7H2_EXODN H6C7H2_EXODN H6C7H7_EXODN H6C7H7_EXODN H6C7J5_EXODN H6C7J5_EXODN H6C8F5_EXODN H6C8F5_EXODN H6C8J2_EXODN H6C8J2_EXODN H6C8W3_EXODN H6C8W3_EXODN H6C9Q4_EXODN H6C9Q4_EXODN H6C9Q8_EXODN H6C9Q8_EXODN H6C9T8_EXODN H6C9T8_EXODN H6CAQ9_EXODN H6CAQ9_EXODN H6BSZ2_EXODN H6BSZ2_EXODN PAC1-2 PAC1-2 H6CB37_EXODN H6CB37_EXODN H6CB83_EXODN H6CB83_EXODN H6BSF8_EXODN H6BSF8_EXODN H6BRS1_EXODN H6BRS1_EXODN H6BRJ4_EXODN H6BRJ4_EXODN H6BQN0_EXODN H6BQN0_EXODN H6BQJ5_EXODN H6BQJ5_EXODN H6BQF5_EXODN H6BQF5_EXODN H6BQB8_EXODN H6BQB8_EXODN H6BPT9_EXODN H6BPT9_EXODN H6BPA4_EXODN H6BPA4_EXODN H6BNW0_EXODN H6BNW0_EXODN H6BNJ3_EXODN H6BNJ3_EXODN H6BNC5_EXODN H6BNC5_EXODN H6BMJ1_EXODN H6BMJ1_EXODN H6BMF0_EXODN H6BMF0_EXODN H6BLK3_EXODN H6BLK3_EXODN H6BKS0_EXODN H6BKS0_EXODN H6BJY6_EXODN H6BJY6_EXODN H6BJU0_EXODN H6BJU0_EXODN H6CC14_EXODN H6CC14_EXODN H6BTV6_EXODN H6BTV6_EXODN H6BUM1_EXODN H6BUM1_EXODN H6BX03_EXODN H6BX03_EXODN H6BY38_EXODN H6BY38_EXODN H6BY96_EXODN H6BY96_EXODN H6BYP7_EXODN H6BYP7_EXODN H6BYZ8_EXODN H6BYZ8_EXODN H6C014_EXODN H6C014_EXODN H6C0H8_EXODN H6C0H8_EXODN H6C015_EXODN H6C015_EXODN H6C0W1_EXODN H6C0W1_EXODN H6C1H4_EXODN H6C1H4_EXODN H6C1X1_EXODN H6C1X1_EXODN H6C255_EXODN H6C255_EXODN H6C2R9_EXODN H6C2R9_EXODN H6C2X1_EXODN H6C2X1_EXODN H6C3B7_EXODN H6C3B7_EXODN H6C3X8_EXODN H6C3X8_EXODN H6C441_EXODN H6C441_EXODN H6C496_EXODN H6C496_EXODN H6C4P3_EXODN H6C4P3_EXODN PAC1 PAC1 H6C540_EXODN H6C540_EXODN H6C5P3_EXODN H6C5P3_EXODN H6C5Q5_EXODN H6C5Q5_EXODN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H6C662_EXODNCAP-Gly domain-containing protein. (854 aa)
H6C6G0_EXODNRibosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (429 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (249 aa)
H6C6P8_EXODNTAP-C domain-containing protein. (412 aa)
H6C7H2_EXODNTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
H6C7H7_EXODNSerine/threonine-protein kinase. (1054 aa)
H6C7J5_EXODNUncharacterized protein. (239 aa)
H6C8F5_EXODNGTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (217 aa)
H6C8J2_EXODNCP-type G domain-containing protein. (552 aa)
H6C8W3_EXODNUncharacterized protein. (270 aa)
H6C9Q4_EXODNABC transporter ATP-binding protein ARB1. (631 aa)
H6C9Q8_EXODNExportin-1. (1072 aa)
H6C9T8_EXODNNUDE_C domain-containing protein. (622 aa)
H6CAQ9_EXODNDynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (801 aa)
H6BSZ2_EXODNCell division cycle 14. (657 aa)
PAC1-2Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (454 aa)
H6CB37_EXODNCyclin-dependent kinase. (288 aa)
H6CB83_EXODNUncharacterized protein. (948 aa)
H6BSF8_EXODNActin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (188 aa)
H6BRS1_EXODNDynein heavy chain, cytoplasmic. (4347 aa)
H6BRJ4_EXODNSUN domain-containing protein. (640 aa)
H6BQN0_EXODNRP/EB family microtubule-associated protein. (261 aa)
H6BQJ5_EXODNKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (777 aa)
H6BQF5_EXODNUncharacterized protein. (348 aa)
H6BQB8_EXODNUncharacterized protein. (763 aa)
H6BPT9_EXODNTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
H6BPA4_EXODNArf-GAP domain-containing protein. (502 aa)
H6BNW0_EXODNKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (985 aa)
H6BNJ3_EXODNSpc7 domain-containing protein. (1763 aa)
H6BNC5_EXODNRibosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (231 aa)
H6BMJ1_EXODNNucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (574 aa)
H6BMF0_EXODNActin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
H6BLK3_EXODNUncharacterized protein. (273 aa)
H6BKS0_EXODNHTH APSES-type domain-containing protein. (394 aa)
H6BJY6_EXODN40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (262 aa)
H6BJU0_EXODNNuclear movement protein nudC. (195 aa)
H6CC14_EXODNUncharacterized protein. (649 aa)
H6BTV6_EXODNAdenosinetriphosphatase. (814 aa)
H6BUM1_EXODNUncharacterized protein. (464 aa)
H6BX03_EXODNTranslation initiation factor RLI1. (603 aa)
H6BY38_EXODNExocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (824 aa)
H6BY96_EXODNX-Pro aminopeptidase. (1261 aa)
H6BYP7_EXODNPH domain-containing protein. (1604 aa)
H6BYZ8_EXODNKinesin family member 18/19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1028 aa)
H6C014_EXODNCP-type G domain-containing protein. (688 aa)
H6C0H8_EXODNKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (861 aa)
H6C015_EXODNUncharacterized protein. (484 aa)
H6C0W1_EXODNProtein transport protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy; Belongs to the SEC16 family. (1963 aa)
H6C1H4_EXODNDynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (98 aa)
H6C1X1_EXODNEssential mitotic spindle pole protein DAM1. (217 aa)
H6C255_EXODNC2H2-type domain-containing protein. (111 aa)
H6C2R9_EXODNActin-like protein; Belongs to the actin family. (382 aa)
H6C2X1_EXODNDynactin 1. (1397 aa)
H6C3B7_EXODNUncharacterized protein. (542 aa)
H6C3X8_EXODNDnaJ protein, subfamily C, member 2. (448 aa)
H6C441_EXODNDnaJ protein, subfamily A, member 5. (547 aa)
H6C496_EXODNCell division control protein 7. (590 aa)
H6C4P3_EXODNSpindle pole body component. (960 aa)
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (432 aa)
H6C540_EXODNNucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (659 aa)
H6C5P3_EXODNCsm1 domain-containing protein. (559 aa)
H6C5Q5_EXODNProtein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (768 aa)
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.