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H6BVT5_EXODN H6BVT5_EXODN MET3 MET3 H6BVQ8_EXODN H6BVQ8_EXODN H6BVQ7_EXODN H6BVQ7_EXODN H6BVJ2_EXODN H6BVJ2_EXODN H6BVD6_EXODN H6BVD6_EXODN H6BV87_EXODN H6BV87_EXODN H6BV59_EXODN H6BV59_EXODN H6BUZ0_EXODN H6BUZ0_EXODN H6BUT3_EXODN H6BUT3_EXODN H6BUH4_EXODN H6BUH4_EXODN H6BUG4_EXODN H6BUG4_EXODN H6BUE4_EXODN H6BUE4_EXODN H6BU31_EXODN H6BU31_EXODN H6BTZ9_EXODN H6BTZ9_EXODN H6BTW9_EXODN H6BTW9_EXODN H6BTW8_EXODN H6BTW8_EXODN H6BTJ3_EXODN H6BTJ3_EXODN H6BT59_EXODN H6BT59_EXODN H6BT56_EXODN H6BT56_EXODN H6BSG9_EXODN H6BSG9_EXODN H6BS39_EXODN H6BS39_EXODN H6BRX9_EXODN H6BRX9_EXODN MDE1 MDE1 H6BRI2_EXODN H6BRI2_EXODN H6BRH7_EXODN H6BRH7_EXODN H6BQT3_EXODN H6BQT3_EXODN H6BQL8_EXODN H6BQL8_EXODN H6BQI4_EXODN H6BQI4_EXODN H6BQD3_EXODN H6BQD3_EXODN ADI1 ADI1 H6BQ64_EXODN H6BQ64_EXODN H6BQ48_EXODN H6BQ48_EXODN H6BPN5_EXODN H6BPN5_EXODN H6BNX6_EXODN H6BNX6_EXODN MRI1 MRI1 H6BM11_EXODN H6BM11_EXODN H6BLN4_EXODN H6BLN4_EXODN H6BL88_EXODN H6BL88_EXODN H6C482_EXODN H6C482_EXODN H6C402_EXODN H6C402_EXODN H6C3Z6_EXODN H6C3Z6_EXODN H6C3P1_EXODN H6C3P1_EXODN H6C3G9_EXODN H6C3G9_EXODN H6C3F5_EXODN H6C3F5_EXODN H6C281_EXODN H6C281_EXODN H6C1Y1_EXODN H6C1Y1_EXODN H6C135_EXODN H6C135_EXODN H6C0Y3_EXODN H6C0Y3_EXODN H6C0Y1_EXODN H6C0Y1_EXODN H6C0L6_EXODN H6C0L6_EXODN H6BZD3_EXODN H6BZD3_EXODN H6BZB6_EXODN H6BZB6_EXODN H6BZB4_EXODN H6BZB4_EXODN H6BZ41_EXODN H6BZ41_EXODN H6BZ31_EXODN H6BZ31_EXODN H6BYM0_EXODN H6BYM0_EXODN H6BYL9_EXODN H6BYL9_EXODN H6BYB5_EXODN H6BYB5_EXODN H6BYA1_EXODN H6BYA1_EXODN H6BY67_EXODN H6BY67_EXODN H6BY57_EXODN H6BY57_EXODN H6BY28_EXODN H6BY28_EXODN H6BY09_EXODN H6BY09_EXODN H6BXX2_EXODN H6BXX2_EXODN H6BXI2_EXODN H6BXI2_EXODN H6BXC1_EXODN H6BXC1_EXODN H6C4I9_EXODN H6C4I9_EXODN H6BX24_EXODN H6BX24_EXODN H6BW36_EXODN H6BW36_EXODN H6CBX5_EXODN H6CBX5_EXODN H6CB86_EXODN H6CB86_EXODN H6CAB5_EXODN H6CAB5_EXODN H6C9W0_EXODN H6C9W0_EXODN H6C9M0_EXODN H6C9M0_EXODN H6C9D6_EXODN H6C9D6_EXODN H6C907_EXODN H6C907_EXODN H6C906_EXODN H6C906_EXODN H6C8Z8_EXODN H6C8Z8_EXODN H6C8Z4_EXODN H6C8Z4_EXODN H6C8V7_EXODN H6C8V7_EXODN H6C8K6_EXODN H6C8K6_EXODN H6C8D3_EXODN H6C8D3_EXODN H6C801_EXODN H6C801_EXODN H6C7L0_EXODN H6C7L0_EXODN H6C7H0_EXODN H6C7H0_EXODN H6C6W6_EXODN H6C6W6_EXODN H6C6V8_EXODN H6C6V8_EXODN H6C648_EXODN H6C648_EXODN H6C5N6_EXODN H6C5N6_EXODN H6C5N1_EXODN H6C5N1_EXODN H6C5L8_EXODN H6C5L8_EXODN H6C4T8_EXODN H6C4T8_EXODN H6C4T3_EXODN H6C4T3_EXODN H6C4M9_EXODN H6C4M9_EXODN H6C4J0_EXODN H6C4J0_EXODN H6BJZ7_EXODN H6BJZ7_EXODN H6BK89_EXODN H6BK89_EXODN H6BKH2_EXODN H6BKH2_EXODN
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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H6BVT5_EXODNZn(2)-C6 fungal-type domain-containing protein. (570 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
H6BVQ8_EXODNPhosphoadenosine phosphosulfate reductase. (301 aa)
H6BVQ7_EXODNPhosphoserine phosphatase. (484 aa)
H6BVJ2_EXODN2,2-dialkylglycine decarboxylase (Pyruvate); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
H6BVD6_EXODNAnthranilate phosphoribosyltransferase. (422 aa)
H6BV87_EXODNGlutamate synthase [NADPH]. (2152 aa)
H6BV59_EXODNBranched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
H6BUZ0_EXODNCysteine synthase. (382 aa)
H6BUT3_EXODNAsparagine synthase (Glutamine-hydrolysing). (561 aa)
H6BUH4_EXODNAsparagine synthase (Glutamine-hydrolysing). (631 aa)
H6BUG4_EXODNAlanine-glyoxylate transaminase. (542 aa)
H6BUE4_EXODNBranched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
H6BU31_EXODNAspartate aminotransferase. (406 aa)
H6BTZ9_EXODNGlutamate 5-kinase. (459 aa)
H6BTW9_EXODNOrnithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (343 aa)
H6BTW8_EXODNHomocysteine S-methyltransferase. (333 aa)
H6BTJ3_EXODNSaccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (374 aa)
H6BT59_EXODNO-acetylhomoserine (Thiol)-lyase. (461 aa)
H6BT56_EXODNAromatic amino acid aminotransferase. (623 aa)
H6BSG9_EXODNMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (788 aa)
H6BS39_EXODNChorismate mutase. (276 aa)
H6BRX9_EXODNUncharacterized protein. (153 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (236 aa)
H6BRI2_EXODNAromatic amino acid aminotransferase I. (561 aa)
H6BRH7_EXODNCarbamoyl-phosphate synthase arginine-specific large chain. (1164 aa)
H6BQT3_EXODNAspartate-semialdehyde dehydrogenase. (366 aa)
H6BQL8_EXODNAcetolactate synthase. (699 aa)
H6BQI4_EXODNArgininosuccinate lyase. (469 aa)
H6BQD3_EXODN3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (385 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (274 aa)
H6BQ64_EXODNAcetolactate synthase I/II/III large subunit; Belongs to the TPP enzyme family. (502 aa)
H6BQ48_EXODN2-isopropylmalate synthase. (678 aa)
H6BPN5_EXODNHomoserine dehydrogenase. (361 aa)
H6BNX6_EXODNOrnithine aminotransferase. (476 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (396 aa)
H6BM11_EXODNAmino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (673 aa)
H6BLN4_EXODNProtein pyrABCN. (2296 aa)
H6BL88_EXODNHomoisocitrate dehydrogenase, mitochondrial. (361 aa)
H6C482_EXODNCystathionine gamma-synthase. (636 aa)
H6C402_EXODNTryptophan synthase. (738 aa)
H6C3Z6_EXODNAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (496 aa)
H6C3P1_EXODN5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase. (413 aa)
H6C3G9_EXODNPyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (334 aa)
H6C3F5_EXODN[methionine synthase] reductase. (644 aa)
H6C281_EXODNSerine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (476 aa)
H6C1Y1_EXODN3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (370 aa)
H6C135_EXODNUncharacterized protein. (243 aa)
H6C0Y3_EXODN5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase. (774 aa)
H6C0Y1_EXODNAcetolactate synthase I/III small subunit. (350 aa)
H6C0L6_EXODNUncharacterized protein. (611 aa)
H6BZD3_EXODNCarbamoyl-phosphate synthase arginine-specific small chain. (481 aa)
H6BZB6_EXODNArginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (481 aa)
H6BZB4_EXODNPyridoxine biosynthesis protein, variant; Belongs to the PdxS/SNZ family. (317 aa)
H6BZ41_EXODNHomoserine O-acetyltransferase. (532 aa)
H6BZ31_EXODNPhosphoserine aminotransferase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
H6BYM0_EXODNPyrroline-5-carboxylate reductase. (330 aa)
H6BYL9_EXODNThreonine aldolase. (337 aa)
H6BYB5_EXODNHomoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (804 aa)
H6BYA1_EXODNChorismate mutase/prephenate dehydratase. (435 aa)
H6BY67_EXODNSerine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (526 aa)
H6BY57_EXODNN-acetyltransferase domain-containing protein. (1689 aa)
H6BY28_EXODNSaccharopine dehydrogenase [NADP+, L-glutamate-forming]. (463 aa)
H6BY09_EXODN1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (260 aa)
H6BXX2_EXODNHomoserine kinase. (365 aa)
H6BXI2_EXODNGlutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (457 aa)
H6BXC1_EXODNArgininosuccinate synthase. (415 aa)
H6C4I9_EXODNKetol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (397 aa)
H6BX24_EXODN5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase. (400 aa)
H6BW36_EXODNAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (217 aa)
H6CBX5_EXODNMultifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (772 aa)
H6CB86_EXODNACPS domain-containing protein. (464 aa)
H6CAB5_EXODNS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (314 aa)
H6C9W0_EXODNGlutamine synthetase. (364 aa)
H6C9M0_EXODN5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase. (402 aa)
H6C9D6_EXODNHomocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family. (499 aa)
H6C907_EXODNAspartate aminotransferase. (417 aa)
H6C906_EXODNPyrroline-5-carboxylate reductase. (288 aa)
H6C8Z8_EXODNUncharacterized protein. (626 aa)
H6C8Z4_EXODNPrephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (416 aa)
H6C8V7_EXODNCysteine synthase. (415 aa)
H6C8K6_EXODNHippurate hydrolase. (428 aa)
H6C8D3_EXODND-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (602 aa)
H6C801_EXODNHomoserine O-acetyltransferase. (510 aa)
H6C7L0_EXODNUncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
H6C7H0_EXODNCystathionine gamma-lyase. (439 aa)
H6C6W6_EXODNAspartate aminotransferase. (412 aa)
H6C6V8_EXODNThreonine aldolase. (396 aa)
H6C648_EXODNMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (648 aa)
H6C5N6_EXODNCystathionine beta-lyase. (464 aa)
H6C5N1_EXODN3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (778 aa)
H6C5L8_EXODNAspartate aminotransferase. (417 aa)
H6C4T8_EXODNCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (552 aa)
H6C4T3_EXODNAnthranilate synthase component I. (525 aa)
H6C4M9_EXODNGlutamate-5-semialdehyde dehydrogenase. (478 aa)
H6C4J0_EXODNThreonine dehydratase. (440 aa)
H6BJZ7_EXODNThreonine dehydratase. (563 aa)
H6BK89_EXODNAPH domain-containing protein. (303 aa)
H6BKH2_EXODNThreonine synthase. (551 aa)
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
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