108 items (Exophiala dermatitidis) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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	H6BKL5_EXODN	Guanine nucleotide-binding protein subunit beta. (353 aa)
	H6CBK2_EXODN	Polycomb protein EED. (550 aa)
	H6CBB4_EXODN	F-box and WD-40 domain-containing protein MET30. (710 aa)
	PAC1-2	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (454 aa)
	H6CAR7_EXODN	F-box and WD-40 domain-containing protein 1/11. (979 aa)
	H6CAJ9_EXODN	WD_REPEATS_REGION domain-containing protein. (626 aa)
	H6C9Y8_EXODN	WD_REPEATS_REGION domain-containing protein. (555 aa)
	H6C9G6_EXODN	Guanine nucleotide-binding protein subunit beta-like protein. (378 aa)
	H6C9G2_EXODN	WD_REPEATS_REGION domain-containing protein. (593 aa)
	H6C9C5_EXODN	WD_REPEATS_REGION domain-containing protein. (672 aa)
	H6C9C4_EXODN	Utp12 domain-containing protein. (916 aa)
	H6C8Y5_EXODN	Uncharacterized protein. (1030 aa)
	H6C8W0_EXODN	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (534 aa)
	H6C8V4_EXODN	Ca2+/calmodulin-dependent protein kinase. (971 aa)
	H6C8R1_EXODN	Transcriptional activator SPT8. (667 aa)
	H6C8Q3_EXODN	Uncharacterized protein. (2554 aa)
	H6C896_EXODN	Triacylglycerol lipase. (1278 aa)
	H6C826_EXODN	F-box and WD-40 domain-containing protein CDC4. (1086 aa)
	H6C7W8_EXODN	WD_REPEATS_REGION domain-containing protein. (639 aa)
	H6C7V9_EXODN	Dynein intermediate chain, cytosolic. (691 aa)
	H6C7B7_EXODN	Pre-mRNA-processing factor 4. (502 aa)
	H6C6F1_EXODN	Histone-binding protein RBBP4. (553 aa)
	H6C602_EXODN	Translation initiation factor eIF-3 subunit 2. (339 aa)
	H6C5M9_EXODN	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (860 aa)
	H6C5E6_EXODN	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (475 aa)
	PAC1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs. (432 aa)
	H6C3G4_EXODN	F-box and WD-40 domain-containing protein CDC4. (681 aa)
	H6C2U3_EXODN	Protein kinase. (533 aa)
	H6C2M1_EXODN	Beta-Ala-His dipeptidase. (1010 aa)
	H6C2L6_EXODN	Coronin; Belongs to the WD repeat coronin family. (603 aa)
	H6C2K6_EXODN	Ca2+/calmodulin-dependent protein kinase. (563 aa)
	H6C2K3_EXODN	Glucose repression regulatory protein TUP1. (1261 aa)
	H6C2D9_EXODN	WD_REPEATS_REGION domain-containing protein. (670 aa)
	H6C1Y3_EXODN	WD_REPEATS_REGION domain-containing protein. (350 aa)
	H6C1U0_EXODN	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1223 aa)
	H6C1C1_EXODN	Uncharacterized protein. (676 aa)
	H6C105_EXODN	WD_REPEATS_REGION domain-containing protein. (583 aa)
	H6C0S7_EXODN	Glucose repression regulatory protein TUP1. (491 aa)
	H6C0P7_EXODN	Cell cycle arrest protein BUB3. (361 aa)
	H6C0P5_EXODN	WD_REPEATS_REGION domain-containing protein. (613 aa)
	H6C0G6_EXODN	WD_REPEATS_REGION domain-containing protein. (1443 aa)
	H6C0C9_EXODN	WD_REPEATS_REGION domain-containing protein. (982 aa)
	H6C082_EXODN	Protein transporter sec13; Belongs to the WD repeat SEC13 family. (325 aa)
	H6BZK1_EXODN	Uncharacterized protein. (463 aa)
	H6BZ57_EXODN	Cyclin-dependent kinase 8/11. (582 aa)
	H6BZ37_EXODN	Uncharacterized protein. (406 aa)
	H6BZ19_EXODN	Double-strand break repair protein MRE11. (1380 aa)
	H6BYY0_EXODN	WD_REPEATS_REGION domain-containing protein. (1607 aa)
	H6BYJ2_EXODN	Glucose repression regulatory protein TUP1. (619 aa)
	H6BYC6_EXODN	Elongator complex protein 2. (817 aa)
	H6BX97_EXODN	Pre-mRNA-processing factor 4. (348 aa)
	H6BX46_EXODN	WD_REPEATS_REGION domain-containing protein. (1011 aa)
	H6BWV3_EXODN	Uncharacterized protein. (410 aa)
	H6BWU3_EXODN	Transcription initiation factor TFIID subunit D4. (912 aa)
	H6BVN2_EXODN	G protein beta subunit-like protein. (422 aa)
	H6BVJ5_EXODN	Phosphoinositide-3-kinase, regulatory subunit 4, p150. (1667 aa)
	H6BVJ4_EXODN	Phosphatidylinositol-bisphosphatase. (1254 aa)
	H6BV44_EXODN	Ca2+/calmodulin-dependent protein kinase. (319 aa)
	H6BUR8_EXODN	WD_REPEATS_REGION domain-containing protein. (546 aa)
	H6BUD3_EXODN	Chromosome transmission fidelity protein 4. (838 aa)
	H6BU86_EXODN	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1090 aa)
	TIF34	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (336 aa)
	H6BTD4_EXODN	WD_REPEATS_REGION domain-containing protein. (1141 aa)
	H6BT49_EXODN	Ca2+/calmodulin-dependent protein kinase. (836 aa)
	H6BT16_EXODN	Histone-binding protein RBBP4. (339 aa)
	H6BSQ5_EXODN	Uncharacterized protein. (1109 aa)
	H6BSL9_EXODN	DUF2415 domain-containing protein. (936 aa)
	H6BSI1_EXODN	Histone acetyltransferase type B subunit 2, variant. (436 aa)
	H6BSH8_EXODN	Transcription initiation factor TFIID subunit D4. (346 aa)
	H6BSG4_EXODN	Periodic tryptophan protein 2. (890 aa)
	H6BS95_EXODN	WD_REPEATS_REGION domain-containing protein. (620 aa)
	H6BS66_EXODN	Histone-binding protein RBBP4. (511 aa)
	CIA1	Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (598 aa)
	H6BS40_EXODN	Mitochondrial division protein 1. (661 aa)
	H6BS31_EXODN	Uncharacterized protein. (393 aa)
	H6BRD0_EXODN	1-alkyl-2-acetylglycerophosphocholine esterase. (741 aa)
	H6BRB0_EXODN	Structure-specific recognition protein 1. (1089 aa)
	H6BR59_EXODN	LisH domain-containing protein. (484 aa)
	H6BR11_EXODN	F-box and WD-40 domain-containing protein 1/11. (720 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (810 aa)
	H6BQ76_EXODN	Glycylpeptide N-tetradecanoyltransferase. (1364 aa)
	H6BQ52_EXODN	Ca2+/calmodulin-dependent protein kinase. (359 aa)
	H6BPY6_EXODN	WD_REPEATS_REGION domain-containing protein. (451 aa)
	H6BPE1_EXODN	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (512 aa)
	H6BNK6_EXODN	Pre-mRNA-processing factor 19. (479 aa)
	H6BNJ6_EXODN	WD_REPEATS_REGION domain-containing protein. (1255 aa)
	H6BNH6_EXODN	Chromatin assembly factor 1 subunit B. (730 aa)
	H6BN83_EXODN	WD_REPEATS_REGION domain-containing protein. (720 aa)
	H6BN74_EXODN	Ca2+/calmodulin-dependent protein kinase. (1087 aa)
	H6BN45_EXODN	Pfs, NACHT and WD domain-containing protein. (525 aa)
	H6BN43_EXODN	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (368 aa)
	H6BN13_EXODN	Uncharacterized protein. (497 aa)
	H6BMS1_EXODN	Uncharacterized protein. (752 aa)
	H6BMR1_EXODN	WD_REPEATS_REGION domain-containing protein. (984 aa)
	H6BMM9_EXODN	Autophagy-like protein 18. (434 aa)
	H6BMM1_EXODN	Protein phosphatase. (803 aa)
	H6BM68_EXODN	WD_REPEATS_REGION domain-containing protein. (594 aa)
	H6BM64_EXODN	WD_REPEATS_REGION domain-containing protein. (937 aa)
	H6BLZ0_EXODN	Cell cycle arrest protein BUB3. (349 aa)
	H6BLY5_EXODN	WD_REPEATS_REGION domain-containing protein. (415 aa)
	H6BLX2_EXODN	WD_REPEATS_REGION domain-containing protein. (447 aa)
	H6BL39_EXODN	Pre-mRNA-splicing factor prp46. (438 aa)
	H6BKP7_EXODN	Glucose repression regulatory protein TUP1. (834 aa)
	H6BKM8_EXODN	WD_REPEATS_REGION domain-containing protein. (354 aa)
	H6BKA2_EXODN	DNA excision repair protein ERCC-8. (564 aa)
	H6BK13_EXODN	Peptidylprolyl isomerase. (617 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (459 aa)
	H6BJT7_EXODN	Glucose repression regulatory protein TUP1. (590 aa)

Your Current Organism:

Exophiala dermatitidis

NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERB1	H6BLX2_EXODN	H6BR01	H6BLX2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.583
ERB1	H6BLY5_EXODN	H6BR01	H6BLY5	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.720
ERB1	H6BM64_EXODN	H6BR01	H6BM64	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.917
ERB1	H6BM68_EXODN	H6BR01	H6BM68	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.871
ERB1	H6BMR1_EXODN	H6BR01	H6BMR1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.825
ERB1	H6BN13_EXODN	H6BR01	H6BN13	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.774
ERB1	H6BN45_EXODN	H6BR01	H6BN45	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pfs, NACHT and WD domain-containing protein.	0.941
ERB1	H6BPY6_EXODN	H6BR01	H6BPY6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.604
ERB1	H6BS66_EXODN	H6BR01	H6BS66	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Histone-binding protein RBBP4.	0.916
ERB1	H6BSG4_EXODN	H6BR01	H6BSG4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Periodic tryptophan protein 2.	0.909
ERB1	H6BUR8_EXODN	H6BR01	H6BUR8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.983
ERB1	H6BWU3_EXODN	H6BR01	H6BWU3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Transcription initiation factor TFIID subunit D4.	0.720
ERB1	H6BYC6_EXODN	H6BR01	H6BYC6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Elongator complex protein 2.	0.436
ERB1	H6BZK1_EXODN	H6BR01	H6BZK1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.632
ERB1	H6C0C9_EXODN	H6BR01	H6C0C9	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.892
ERB1	H6C0P5_EXODN	H6BR01	H6C0P5	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.720
ERB1	H6C105_EXODN	H6BR01	H6C105	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.720
ERB1	H6C1C1_EXODN	H6BR01	H6C1C1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.720
ERB1	H6C2D9_EXODN	H6BR01	H6C2D9	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.720
ERB1	H6C2U3_EXODN	H6BR01	H6C2U3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein kinase.	0.667

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