STRINGSTRING
H6C5Z0_EXODN H6C5Z0_EXODN H6CC31_EXODN H6CC31_EXODN H6CC30_EXODN H6CC30_EXODN ADK1 ADK1 H6CBL4_EXODN H6CBL4_EXODN H6CB56_EXODN H6CB56_EXODN H6CAS6_EXODN H6CAS6_EXODN H6CAK2_EXODN H6CAK2_EXODN H6CAJ5_EXODN H6CAJ5_EXODN H6CAA2_EXODN H6CAA2_EXODN H6CA25_EXODN H6CA25_EXODN H6C9T2_EXODN H6C9T2_EXODN H6C8X6_EXODN H6C8X6_EXODN ADK2 ADK2 H6C8J3_EXODN H6C8J3_EXODN H6C871_EXODN H6C871_EXODN H6C7D0_EXODN H6C7D0_EXODN H6C6Y4_EXODN H6C6Y4_EXODN H6C6W0_EXODN H6C6W0_EXODN H6C6K0_EXODN H6C6K0_EXODN H6C693_EXODN H6C693_EXODN H6C649_EXODN H6C649_EXODN H6C635_EXODN H6C635_EXODN H6C590_EXODN H6C590_EXODN H6C538_EXODN H6C538_EXODN H6C396_EXODN H6C396_EXODN H6C2F1_EXODN H6C2F1_EXODN H6C140_EXODN H6C140_EXODN H6C028_EXODN H6C028_EXODN H6BZZ7_EXODN H6BZZ7_EXODN H6BZX4_EXODN H6BZX4_EXODN H6BZL5_EXODN H6BZL5_EXODN H6BYY5_EXODN H6BYY5_EXODN H6BYE7_EXODN H6BYE7_EXODN H6BYE6_EXODN H6BYE6_EXODN H6BYD4_EXODN H6BYD4_EXODN H6BY92_EXODN H6BY92_EXODN H6BXY1_EXODN H6BXY1_EXODN H6BXX1_EXODN H6BXX1_EXODN H6BX16_EXODN H6BX16_EXODN H6BWJ6_EXODN H6BWJ6_EXODN H6BW07_EXODN H6BW07_EXODN H6BVL4_EXODN H6BVL4_EXODN H6BVK0_EXODN H6BVK0_EXODN H6BVJ1_EXODN H6BVJ1_EXODN H6BVG7_EXODN H6BVG7_EXODN H6BV91_EXODN H6BV91_EXODN H6BV42_EXODN H6BV42_EXODN H6BUX8_EXODN H6BUX8_EXODN H6BUV3_EXODN H6BUV3_EXODN H6BUT7_EXODN H6BUT7_EXODN H6BUI0_EXODN H6BUI0_EXODN H6BSH2_EXODN H6BSH2_EXODN H6BS63_EXODN H6BS63_EXODN H6BS37_EXODN H6BS37_EXODN H6BS25_EXODN H6BS25_EXODN H6BRU3_EXODN H6BRU3_EXODN H6BRN3_EXODN H6BRN3_EXODN H6BRF0_EXODN H6BRF0_EXODN H6BR46_EXODN H6BR46_EXODN H6BQF0_EXODN H6BQF0_EXODN H6BQ36_EXODN H6BQ36_EXODN H6BPA1_EXODN H6BPA1_EXODN H6BP54_EXODN H6BP54_EXODN H6BN12_EXODN H6BN12_EXODN H6BMU7_EXODN H6BMU7_EXODN H6BLW8_EXODN H6BLW8_EXODN H6BLN4_EXODN H6BLN4_EXODN H6BLE6_EXODN H6BLE6_EXODN H6BL78_EXODN H6BL78_EXODN H6BL60_EXODN H6BL60_EXODN H6BKP8_EXODN H6BKP8_EXODN H6BKN0_EXODN H6BKN0_EXODN H6BK61_EXODN H6BK61_EXODN H6BJS9_EXODN H6BJS9_EXODN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H6C5Z0_EXODNPhosphoglycolate phosphatase. (252 aa)
H6CC31_EXODNUncharacterized protein. (76 aa)
H6CC30_EXODNUncharacterized protein. (453 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (273 aa)
H6CBL4_EXODN3-carboxy-cis,cis-muconate cycloisomerase. (453 aa)
H6CB56_EXODNdUTP pyrophosphatase. (203 aa)
H6CAS6_EXODNPhosphoribosylaminoimidazole-succinocarboxamide synthase. (306 aa)
H6CAK2_EXODNFormyltetrahydrofolate deformylase. (353 aa)
H6CAJ5_EXODNBH4_2 domain-containing protein. (486 aa)
H6CAA2_EXODNPhosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (606 aa)
H6CA25_EXODNThymidylate synthase. (385 aa)
H6C9T2_EXODNdCMP deaminase. (434 aa)
H6C8X6_EXODNThioredoxin domain-containing protein. (225 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
H6C8J3_EXODNGlycerol 3-phosphatase 1. (240 aa)
H6C871_EXODNCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (600 aa)
H6C7D0_EXODNAMP deaminase. (1146 aa)
H6C6Y4_EXODNOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (273 aa)
H6C6W0_EXODNAcyl_transf_3 domain-containing protein. (548 aa)
H6C6K0_EXODNUridine kinase; Belongs to the uridine kinase family. (478 aa)
H6C693_EXODNAmidophosphoribosyltransferase. (592 aa)
H6C649_EXODNOrotate phosphoribosyltransferase. (245 aa)
H6C635_EXODNMetallophos domain-containing protein. (608 aa)
H6C590_EXODNUncharacterized protein. (429 aa)
H6C538_EXODNDihydroorotate reductase PyrE. (663 aa)
H6C396_EXODNAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
H6C2F1_EXODNGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (462 aa)
H6C140_EXODNNudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (302 aa)
H6C028_EXODNPhosphoglycolate phosphatase. (248 aa)
H6BZZ7_EXODN5'-nucleotidase; Belongs to the 5'-nucleotidase family. (632 aa)
H6BZX4_EXODNInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (550 aa)
H6BZL5_EXODNCytidylate kinase; Belongs to the adenylate kinase family. (388 aa)
H6BYY5_EXODNAdenosine kinase. (348 aa)
H6BYE7_EXODNAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (193 aa)
H6BYE6_EXODNInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (204 aa)
H6BYD4_EXODNUracil phosphoribosyltransferase. (248 aa)
H6BY92_EXODNImportin N-terminal domain-containing protein. (1011 aa)
H6BXY1_EXODNADP-ribose pyrophosphatase. (270 aa)
H6BXX1_EXODNATP-grasp domain-containing protein. (795 aa)
H6BX16_EXODNNucleoside diphosphate kinase. (153 aa)
H6BWJ6_EXODNUncharacterized protein. (438 aa)
H6BW07_EXODNGlutaredoxin domain-containing protein. (270 aa)
H6BVL4_EXODNGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (477 aa)
H6BVK0_EXODNApyrase; Belongs to the GDA1/CD39 NTPase family. (703 aa)
H6BVJ1_EXODNZn(2)-C6 fungal-type domain-containing protein. (701 aa)
H6BVG7_EXODNDihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. (373 aa)
H6BV91_EXODNUncharacterized protein. (330 aa)
H6BV42_EXODNGuanylate kinase. (278 aa)
H6BUX8_EXODNAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (420 aa)
H6BUV3_EXODNPhosphoribosylformylglycinamidine synthase. (1379 aa)
H6BUT7_EXODNAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (453 aa)
H6BUI0_EXODNRibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (918 aa)
H6BSH2_EXODNThymidylate kinase. (226 aa)
H6BS63_EXODNUncharacterized protein. (131 aa)
H6BS37_EXODNGMP synthase. (544 aa)
H6BS25_EXODNGlutamine synthetase. (364 aa)
H6BRU3_EXODNUncharacterized protein. (273 aa)
H6BRN3_EXODNAdenine phosphoribosyltransferase. (213 aa)
H6BRF0_EXODNZn(2)-C6 fungal-type domain-containing protein. (745 aa)
H6BR46_EXODNCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (162 aa)
H6BQF0_EXODNAcyl_transf_3 domain-containing protein. (464 aa)
H6BQ36_EXODNAmidohydro-rel domain-containing protein. (355 aa)
H6BPA1_EXODNChlorohydrolase. (510 aa)
H6BP54_EXODNGuanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. (576 aa)
H6BN12_EXODNUridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (238 aa)
H6BMU7_EXODNBifunctional purine biosynthesis protein ADE17. (598 aa)
H6BLW8_EXODNPhosphoribosylglycinamide formyltransferase. (257 aa)
H6BLN4_EXODNProtein pyrABCN. (2296 aa)
H6BLE6_EXODNPhosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (603 aa)
H6BL78_EXODNFungal_trans domain-containing protein. (631 aa)
H6BL60_EXODNUncharacterized protein. (411 aa)
H6BKP8_EXODNThioredoxin; Belongs to the thioredoxin family. (110 aa)
H6BKN0_EXODNRibonucleoside-diphosphate reductase small chain. (417 aa)
H6BK61_EXODNGlutaredoxin 3. (102 aa)
H6BJS9_EXODNProtein-tyrosine phosphatase. (302 aa)
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
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