STRINGSTRING
H6BLR2_EXODN H6BLR2_EXODN H6CAC8_EXODN H6CAC8_EXODN H6C9T1_EXODN H6C9T1_EXODN H6C8V9_EXODN H6C8V9_EXODN H6C7Z0_EXODN H6C7Z0_EXODN H6C7W9_EXODN H6C7W9_EXODN H6C6S2_EXODN H6C6S2_EXODN H6C639_EXODN H6C639_EXODN H6C4W6_EXODN H6C4W6_EXODN H6C4K8_EXODN H6C4K8_EXODN H6C4B6_EXODN H6C4B6_EXODN H6C3T1_EXODN H6C3T1_EXODN H6C364_EXODN H6C364_EXODN H6C345_EXODN H6C345_EXODN H6C2P6_EXODN H6C2P6_EXODN MDM34 MDM34 H6C2J5_EXODN H6C2J5_EXODN H6C2J1_EXODN H6C2J1_EXODN H6C2A3_EXODN H6C2A3_EXODN H6C1K4_EXODN H6C1K4_EXODN H6C1C8_EXODN H6C1C8_EXODN H6BZW5_EXODN H6BZW5_EXODN H6BZ37_EXODN H6BZ37_EXODN H6BYY1_EXODN H6BYY1_EXODN H6BYJ1_EXODN H6BYJ1_EXODN H6BYC9_EXODN H6BYC9_EXODN H6BXY4_EXODN H6BXY4_EXODN H6BXF3_EXODN H6BXF3_EXODN H6BXB2_EXODN H6BXB2_EXODN H6BX96_EXODN H6BX96_EXODN H6BX89_EXODN H6BX89_EXODN H6BWS5_EXODN H6BWS5_EXODN H6BWQ7_EXODN H6BWQ7_EXODN H6BVS4_EXODN H6BVS4_EXODN H6BVR5_EXODN H6BVR5_EXODN H6BVJ5_EXODN H6BVJ5_EXODN H6BVC1_EXODN H6BVC1_EXODN H6BVC0_EXODN H6BVC0_EXODN H6BVB4_EXODN H6BVB4_EXODN H6BV28_EXODN H6BV28_EXODN H6BTP2_EXODN H6BTP2_EXODN H6BS21_EXODN H6BS21_EXODN H6BQP9_EXODN H6BQP9_EXODN H6BQM1_EXODN H6BQM1_EXODN H6BQC8_EXODN H6BQC8_EXODN H6BPU6_EXODN H6BPU6_EXODN H6BPN7_EXODN H6BPN7_EXODN H6BP47_EXODN H6BP47_EXODN H6BP45_EXODN H6BP45_EXODN H6BP44_EXODN H6BP44_EXODN H6BP31_EXODN H6BP31_EXODN H6BP29_EXODN H6BP29_EXODN H6BNN2_EXODN H6BNN2_EXODN H6BNI1_EXODN H6BNI1_EXODN H6BNF7_EXODN H6BNF7_EXODN H6BMM9_EXODN H6BMM9_EXODN H6BLN9_EXODN H6BLN9_EXODN H6BLH3_EXODN H6BLH3_EXODN H6BKL7_EXODN H6BKL7_EXODN H6BKA9_EXODN H6BKA9_EXODN H6BK64_EXODN H6BK64_EXODN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H6BLR2_EXODNUncharacterized protein. (171 aa)
H6CAC8_EXODNAutophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (1020 aa)
H6C9T1_EXODNUbiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (765 aa)
H6C8V9_EXODNBeclin 1. (520 aa)
H6C7Z0_EXODNDynein light intermediate chain 1, cytosolic. (655 aa)
H6C7W9_EXODNUncharacterized protein. (270 aa)
H6C6S2_EXODNCasein kinase II subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
H6C639_EXODNAutophagy-related protein 3. (372 aa)
H6C4W6_EXODNAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (1060 aa)
H6C4K8_EXODNAMPK1_CBM domain-containing protein. (559 aa)
H6C4B6_EXODNUncharacterized protein. (233 aa)
H6C3T1_EXODNCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (480 aa)
H6C364_EXODNCentrin-2. (236 aa)
H6C345_EXODNUncharacterized protein. (260 aa)
H6C2P6_EXODNAMPK1_CBM domain-containing protein. (316 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (615 aa)
H6C2J5_EXODNMitochondrial import receptor subunit tom-70. (623 aa)
H6C2J1_EXODNNon-specific serine/threonine protein kinase. (900 aa)
H6C2A3_EXODNUncharacterized protein. (150 aa)
H6C1K4_EXODNUbiquitin-40S ribosomal protein S27a. (154 aa)
H6C1C8_EXODNUbiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (157 aa)
H6BZW5_EXODNDJ-1_PfpI domain-containing protein. (269 aa)
H6BZ37_EXODNUncharacterized protein. (406 aa)
H6BYY1_EXODNUbiquitin-conjugating enzyme E2 35; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
H6BYJ1_EXODNUncharacterized protein. (54 aa)
H6BYC9_EXODNMitochondrial import receptor subunit TOM40. (360 aa)
H6BXY4_EXODNUncharacterized protein. (220 aa)
H6BXF3_EXODNUncharacterized protein. (221 aa)
H6BXB2_EXODNUbiquitin-conjugating enzyme E2. (139 aa)
H6BX96_EXODNCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (275 aa)
H6BX89_EXODNNon-specific serine/threonine protein kinase. (1069 aa)
H6BWS5_EXODNUncharacterized protein. (304 aa)
H6BWQ7_EXODNDJ-1_PfpI domain-containing protein. (287 aa)
H6BVS4_EXODNUncharacterized protein. (132 aa)
H6BVR5_EXODNUncharacterized protein. (217 aa)
H6BVJ5_EXODNPhosphoinositide-3-kinase, regulatory subunit 4, p150. (1667 aa)
H6BVC1_EXODNCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (462 aa)
H6BVC0_EXODNZn(2)-C6 fungal-type domain-containing protein. (742 aa)
H6BVB4_EXODNBZIP domain-containing protein. (292 aa)
H6BV28_EXODNUncharacterized protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (569 aa)
H6BTP2_EXODNUncharacterized protein. (818 aa)
H6BS21_EXODNPhosphatidylinositol 3-kinase VPS34. (939 aa)
H6BQP9_EXODNAutophagy-related protein. (118 aa)
H6BQM1_EXODNTPR_REGION domain-containing protein. (645 aa)
H6BQC8_EXODN5'-AMP-activated protein kinase, regulatory beta subunit. (476 aa)
H6BPU6_EXODNUncharacterized protein. (189 aa)
H6BPN7_EXODNAutophagy-like protein 11. (1454 aa)
H6BP47_EXODNUncharacterized protein. (640 aa)
H6BP45_EXODNDOA4-independent degradation protein 4. (209 aa)
H6BP44_EXODNTransmembrane GTPase Fzo1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (938 aa)
H6BP31_EXODNUncharacterized protein. (509 aa)
H6BP29_EXODNUncharacterized protein. (154 aa)
H6BNN2_EXODNSerine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2918 aa)
H6BNI1_EXODNSerine/threonine protein kinase. (999 aa)
H6BNF7_EXODNAutophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (321 aa)
H6BMM9_EXODNAutophagy-like protein 18. (434 aa)
H6BLN9_EXODNUncharacterized protein. (226 aa)
H6BLH3_EXODNUnc51-like kinase. (985 aa)
H6BKL7_EXODNATG16 domain-containing protein. (207 aa)
H6BKA9_EXODNAutophagy_act_C domain-containing protein. (219 aa)
H6BK64_EXODNProtein-tyrosine phosphatase. (1034 aa)
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.