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H6C1K4_EXODN H6C1K4_EXODN H6C1Z4_EXODN H6C1Z4_EXODN H6C2P3_EXODN H6C2P3_EXODN H6C3H4_EXODN H6C3H4_EXODN H6C6H2_EXODN H6C6H2_EXODN H6C8F7_EXODN H6C8F7_EXODN H6CAM7_EXODN H6CAM7_EXODN H6CBB0_EXODN H6CBB0_EXODN H6BWB2_EXODN H6BWB2_EXODN H6BVB4_EXODN H6BVB4_EXODN H6BWK4_EXODN H6BWK4_EXODN H6BSJ9_EXODN H6BSJ9_EXODN H6BRU9_EXODN H6BRU9_EXODN MCM7 MCM7 H6BLW5_EXODN H6BLW5_EXODN H6BKF2_EXODN H6BKF2_EXODN H6BKD6_EXODN H6BKD6_EXODN H6BYX1_EXODN H6BYX1_EXODN H6BZ86_EXODN H6BZ86_EXODN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H6C1K4_EXODNUbiquitin-40S ribosomal protein S27a. (154 aa)
H6C1Z4_EXODNDNA helicase; Belongs to the MCM family. (847 aa)
H6C2P3_EXODNCyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (333 aa)
H6C3H4_EXODNNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (416 aa)
H6C6H2_EXODNOrigin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (766 aa)
H6C8F7_EXODNUncharacterized protein. (455 aa)
H6CAM7_EXODNDNA helicase; Belongs to the MCM family. (889 aa)
H6CBB0_EXODNDNA helicase; Belongs to the MCM family. (922 aa)
H6BWB2_EXODNUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (333 aa)
H6BVB4_EXODNBZIP domain-containing protein. (292 aa)
H6BWK4_EXODNG2/mitotic-specific cyclin-B; Belongs to the cyclin family. (481 aa)
H6BSJ9_EXODNDNA helicase; Belongs to the MCM family. (726 aa)
H6BRU9_EXODNUncharacterized protein. (505 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (809 aa)
H6BLW5_EXODNCell division control protein; Belongs to the CDC6/cdc18 family. (606 aa)
H6BKF2_EXODNG2/mitotic-specific cyclin 3/4; Belongs to the cyclin family. (689 aa)
H6BKD6_EXODNG1/S-specific cyclin CLN3; Belongs to the cyclin family. (409 aa)
H6BYX1_EXODNRING-box protein 1. (124 aa)
H6BZ86_EXODNDNA helicase; Belongs to the MCM family. (965 aa)
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
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