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H6BZ24_EXODN H6BZ24_EXODN H6C3D6_EXODN H6C3D6_EXODN H6C396_EXODN H6C396_EXODN H6C377_EXODN H6C377_EXODN H6C2U1_EXODN H6C2U1_EXODN H6C2S2_EXODN H6C2S2_EXODN H6C2M4_EXODN H6C2M4_EXODN H6C2F1_EXODN H6C2F1_EXODN H6C2E9_EXODN H6C2E9_EXODN H6C231_EXODN H6C231_EXODN H6C1Z5_EXODN H6C1Z5_EXODN H6C1N0_EXODN H6C1N0_EXODN H6C1M4_EXODN H6C1M4_EXODN H6C1M3_EXODN H6C1M3_EXODN H6C1K7_EXODN H6C1K7_EXODN H6C1H5_EXODN H6C1H5_EXODN AAH1 AAH1 H6C035_EXODN H6C035_EXODN H6BZZ7_EXODN H6BZZ7_EXODN H6BK18_EXODN H6BK18_EXODN H6BKM5_EXODN H6BKM5_EXODN H6BKN0_EXODN H6BKN0_EXODN H6BL60_EXODN H6BL60_EXODN H6BL84_EXODN H6BL84_EXODN H6BLE6_EXODN H6BLE6_EXODN H6BLW8_EXODN H6BLW8_EXODN H6BM03_EXODN H6BM03_EXODN H6BM44_EXODN H6BM44_EXODN H6BMU7_EXODN H6BMU7_EXODN H6BNS5_EXODN H6BNS5_EXODN H6BNT5_EXODN H6BNT5_EXODN H6BP54_EXODN H6BP54_EXODN H6BP92_EXODN H6BP92_EXODN H6BPA1_EXODN H6BPA1_EXODN H6BPS1_EXODN H6BPS1_EXODN H6BPS4_EXODN H6BPS4_EXODN H6BQ36_EXODN H6BQ36_EXODN H6BQB1_EXODN H6BQB1_EXODN H6BQC1_EXODN H6BQC1_EXODN H6BQK0_EXODN H6BQK0_EXODN H6BQL0_EXODN H6BQL0_EXODN H6BRF0_EXODN H6BRF0_EXODN H6BRM7_EXODN H6BRM7_EXODN H6BRN3_EXODN H6BRN3_EXODN H6BRU3_EXODN H6BRU3_EXODN H6BS37_EXODN H6BS37_EXODN H6BSH5_EXODN H6BSH5_EXODN H6BT02_EXODN H6BT02_EXODN H6BT48_EXODN H6BT48_EXODN H6BTX8_EXODN H6BTX8_EXODN H6BU85_EXODN H6BU85_EXODN H6BUI0_EXODN H6BUI0_EXODN H6BUT7_EXODN H6BUT7_EXODN H6BUV3_EXODN H6BUV3_EXODN H6BUX8_EXODN H6BUX8_EXODN H6BV42_EXODN H6BV42_EXODN H6BV58_EXODN H6BV58_EXODN H6BVJ1_EXODN H6BVJ1_EXODN H6BVK0_EXODN H6BVK0_EXODN H6BVL1_EXODN H6BVL1_EXODN MET3 MET3 H6BW36_EXODN H6BW36_EXODN H6BWK5_EXODN H6BWK5_EXODN H6BWN1_EXODN H6BWN1_EXODN H6BWT7_EXODN H6BWT7_EXODN H6BX16_EXODN H6BX16_EXODN H6BXW8_EXODN H6BXW8_EXODN H6BXX1_EXODN H6BXX1_EXODN H6BXY1_EXODN H6BXY1_EXODN H6BY92_EXODN H6BY92_EXODN H6BYE6_EXODN H6BYE6_EXODN H6BYE7_EXODN H6BYE7_EXODN H6BYH2_EXODN H6BYH2_EXODN H6BYY5_EXODN H6BYY5_EXODN H6C3K0_EXODN H6C3K0_EXODN H6BZT8_EXODN H6BZT8_EXODN H6BZX4_EXODN H6BZX4_EXODN H6BZZ1_EXODN H6BZZ1_EXODN H6C8Y9_EXODN H6C8Y9_EXODN H6CAA2_EXODN H6CAA2_EXODN H6CAJ5_EXODN H6CAJ5_EXODN H6CAS6_EXODN H6CAS6_EXODN H6CBF0_EXODN H6CBF0_EXODN H6CBL4_EXODN H6CBL4_EXODN ADK1 ADK1 ADK2 ADK2 H6C8H6_EXODN H6C8H6_EXODN H6C8A1_EXODN H6C8A1_EXODN H6C7W0_EXODN H6C7W0_EXODN H6C7D0_EXODN H6C7D0_EXODN H6C6V3_EXODN H6C6V3_EXODN H6C693_EXODN H6C693_EXODN H6C635_EXODN H6C635_EXODN H6C5S4_EXODN H6C5S4_EXODN H6C5N0_EXODN H6C5N0_EXODN H6C4T1_EXODN H6C4T1_EXODN H6C4L6_EXODN H6C4L6_EXODN H6C4G4_EXODN H6C4G4_EXODN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H6BZ24_EXODNTAF4 domain-containing protein. (573 aa)
H6C3D6_EXODNtRNA pseudouridine synthase A. (700 aa)
H6C396_EXODNAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
H6C377_EXODNXanthine dehydrogenase. (1360 aa)
H6C2U1_EXODNHit family protein 1. (134 aa)
H6C2S2_EXODNAdenosinetriphosphatase. (1120 aa)
H6C2M4_EXODNHemolysin. (757 aa)
H6C2F1_EXODNGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (462 aa)
H6C2E9_EXODNUncharacterized protein. (453 aa)
H6C231_EXODNBiphenyl-2,3-diol 1,2-dioxygenase. (141 aa)
H6C1Z5_EXODNUncharacterized protein. (884 aa)
H6C1N0_EXODNMFS transporter, metabolite:H+ symporter. (606 aa)
H6C1M4_EXODNUrease; In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (836 aa)
H6C1M3_EXODNUncharacterized protein. (507 aa)
H6C1K7_EXODN5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (128 aa)
H6C1H5_EXODNUncharacterized protein. (118 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (348 aa)
H6C035_EXODN3',5'-cyclic-nucleotide phosphodiesterase. (642 aa)
H6BZZ7_EXODN5'-nucleotidase; Belongs to the 5'-nucleotidase family. (632 aa)
H6BK18_EXODNF-box and leucine-rich repeat protein 2. (751 aa)
H6BKM5_EXODNOHCU_decarbox domain-containing protein. (177 aa)
H6BKN0_EXODNRibonucleoside-diphosphate reductase small chain. (417 aa)
H6BL60_EXODNUncharacterized protein. (411 aa)
H6BL84_EXODNPyruvate kinase; Belongs to the pyruvate kinase family. (524 aa)
H6BLE6_EXODNPhosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (603 aa)
H6BLW8_EXODNPhosphoribosylglycinamide formyltransferase. (257 aa)
H6BM03_EXODNPribosyltran domain-containing protein. (203 aa)
H6BM44_EXODNDiphthami_syn_2 domain-containing protein. (922 aa)
H6BMU7_EXODNBifunctional purine biosynthesis protein ADE17. (598 aa)
H6BNS5_EXODNIMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (389 aa)
H6BNT5_EXODNCN hydrolase domain-containing protein. (272 aa)
H6BP54_EXODNGuanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. (576 aa)
H6BP92_EXODNUncharacterized protein. (562 aa)
H6BPA1_EXODNChlorohydrolase. (510 aa)
H6BPS1_EXODNPseudoU_synth_1 domain-containing protein. (713 aa)
H6BPS4_EXODNRibose-phosphate pyrophosphokinase. (449 aa)
H6BQ36_EXODNAmidohydro-rel domain-containing protein. (355 aa)
H6BQB1_EXODNUncharacterized protein. (180 aa)
H6BQC1_EXODNAcid phosphatase. (761 aa)
H6BQK0_EXODNPhosphoglucomutase; Belongs to the phosphohexose mutase family. (555 aa)
H6BQL0_EXODNAllantoicase. (400 aa)
H6BRF0_EXODNZn(2)-C6 fungal-type domain-containing protein. (745 aa)
H6BRM7_EXODNPhosphodiesterase. (1014 aa)
H6BRN3_EXODNAdenine phosphoribosyltransferase. (213 aa)
H6BRU3_EXODNUncharacterized protein. (273 aa)
H6BS37_EXODNGMP synthase. (544 aa)
H6BSH5_EXODNExopolyphosphatase. (568 aa)
H6BT02_EXODNOBG-type G domain-containing protein. (414 aa)
H6BT48_EXODNMFS transporter, metabolite:H+ symporter. (589 aa)
H6BTX8_EXODNGRIP domain-containing protein. (645 aa)
H6BU85_EXODNObg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (393 aa)
H6BUI0_EXODNRibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (918 aa)
H6BUT7_EXODNAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (453 aa)
H6BUV3_EXODNPhosphoribosylformylglycinamidine synthase. (1379 aa)
H6BUX8_EXODNAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (420 aa)
H6BV42_EXODNGuanylate kinase. (278 aa)
H6BV58_EXODN5'/3'-nucleotidase SurE. (359 aa)
H6BVJ1_EXODNZn(2)-C6 fungal-type domain-containing protein. (701 aa)
H6BVK0_EXODNApyrase; Belongs to the GDA1/CD39 NTPase family. (703 aa)
H6BVL1_EXODNGMP synthase (Glutamine-hydrolysing). (255 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
H6BW36_EXODNAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (217 aa)
H6BWK5_EXODNHit-like protein. (274 aa)
H6BWN1_EXODNMFS transporter, metabolite:H+ symporter. (554 aa)
H6BWT7_EXODNProtein phosphatase. (446 aa)
H6BX16_EXODNNucleoside diphosphate kinase. (153 aa)
H6BXW8_EXODNUncharacterized protein. (236 aa)
H6BXX1_EXODNATP-grasp domain-containing protein. (795 aa)
H6BXY1_EXODNADP-ribose pyrophosphatase. (270 aa)
H6BY92_EXODNImportin N-terminal domain-containing protein. (1011 aa)
H6BYE6_EXODNInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (204 aa)
H6BYE7_EXODNAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (193 aa)
H6BYH2_EXODNUncharacterized protein. (594 aa)
H6BYY5_EXODNAdenosine kinase. (348 aa)
H6C3K0_EXODNAdenylate cyclase. (2040 aa)
H6BZT8_EXODNUncharacterized protein. (1338 aa)
H6BZX4_EXODNInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (550 aa)
H6BZZ1_EXODNAdenosinetriphosphatase. (1690 aa)
H6C8Y9_EXODNUricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (296 aa)
H6CAA2_EXODNPhosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (606 aa)
H6CAJ5_EXODNBH4_2 domain-containing protein. (486 aa)
H6CAS6_EXODNPhosphoribosylaminoimidazole-succinocarboxamide synthase. (306 aa)
H6CBF0_EXODNRibose-phosphate pyrophosphokinase. (533 aa)
H6CBL4_EXODN3-carboxy-cis,cis-muconate cycloisomerase. (453 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (273 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
H6C8H6_EXODNAdenosine deaminase. (618 aa)
H6C8A1_EXODNNudix hydrolase domain-containing protein. (158 aa)
H6C7W0_EXODNUreidoglycolate hydrolase. (270 aa)
H6C7D0_EXODNAMP deaminase. (1146 aa)
H6C6V3_EXODNATP adenylyltransferase. (342 aa)
H6C693_EXODNAmidophosphoribosyltransferase. (592 aa)
H6C635_EXODNMetallophos domain-containing protein. (608 aa)
H6C5S4_EXODNBis(5'-adenosyl)-triphosphatase. (194 aa)
H6C5N0_EXODNAdenylate cyclase. (455 aa)
H6C4T1_EXODNRibose-phosphate pyrophosphokinase. (380 aa)
H6C4L6_EXODNAllantoinase. (547 aa)
H6C4G4_EXODNUncharacterized protein. (331 aa)
Your Current Organism:
Exophiala dermatitidis
NCBI taxonomy Id: 858893
Other names: E. dermatitidis NIH/UT8656, Exophiala dermatitidis NIH 8656, Exophiala dermatitidis NIH/UT8656, Wangiella dermatitidis NIH 8656
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