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cbiO cbiO cbiO-2 cbiO-2 ybaF ybaF thiC thiC yhfU yhfU prpE prpE yjbQ yjbQ tenA tenA tenI tenI goxB goxB thiS thiS thiG thiG thiF thiF yjbV yjbV ykoC ykoC AMK71958.1 AMK71958.1 ykoE ykoE ykoF ykoF ykoG ykoG ykoH ykoH AMK71963.1 AMK71963.1 ykoJ ykoJ ykzD ykzD AMK71966.1 AMK71966.1 AMK71967.1 AMK71967.1 ylmB ylmB tdh tdh kbl kbl AMK72549.1 AMK72549.1 AMK72550.1 AMK72550.1 AMK72552.1 AMK72552.1 AMK72553.1 AMK72553.1 ypaA ypaA AMK73418.1 AMK73418.1 bioI bioI bioB bioB bioD bioD AMK73421.1 AMK73421.1 bioA bioA bioW bioW yuaJ yuaJ yuiG yuiG AMK73711.1 AMK73711.1 AMK73712.1 AMK73712.1 AMK73713.1 AMK73713.1 AMK73714.1 AMK73714.1 AMK73715.1 AMK73715.1 AMK73716.1 AMK73716.1 AMK73717.1 AMK73717.1 AMK73718.1 AMK73718.1 kbl-2 kbl-2 thiD thiD thiE thiE thiM thiM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cbiOEnergy-coupling factor transporter ATPase; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (281 aa)
cbiO-2Energy-coupling factor transporter ATPase; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (289 aa)
ybaFCobalt ABC transporter permease; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (265 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (590 aa)
yhfUBiotin biosynthesis protein BioY; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
prpEHypothetical protein; Asymmetrically hydrolyzes Ap4p to yield AMP and ATP. (244 aa)
yjbQSodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (614 aa)
tenAThiaminase II; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (236 aa)
tenITranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
goxBGlycine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
thiSThiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (254 aa)
thiFThiamine biosynthesis protein MoeB; Catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
yjbVHydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
ykoCThiamine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
AMK71958.1Cobalt ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
ykoEThiamine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
ykoFThiamine-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
ykoGPhoB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
ykoHHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
AMK71963.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
ykoJHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
ykzDHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (45 aa)
AMK71966.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (59 aa)
AMK71967.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (40 aa)
ylmBAcetylornithine deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (347 aa)
kbl8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (392 aa)
AMK72549.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (381 aa)
AMK72550.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (276 aa)
AMK72552.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (80 aa)
AMK72553.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
ypaARiboflavin transporter FmnP; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. (190 aa)
AMK73418.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
bioICytochrome; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family. (395 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (335 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (231 aa)
AMK73421.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (448 aa)
bioW6-carboxyhexanoate--CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. (224 aa)
yuaJEnergy-coupled thiamine transporter ThiT; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
yuiGBioY family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
AMK73711.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (398 aa)
AMK73712.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
AMK73713.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (368 aa)
AMK73714.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (413 aa)
AMK73715.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (174 aa)
AMK73716.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (444 aa)
AMK73717.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (430 aa)
AMK73718.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (427 aa)
kbl-2Glycine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
thiDHydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (222 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (272 aa)
Your Current Organism:
Bacillus subtilis natto
NCBI taxonomy Id: 86029
Other names: B. subtilis subsp. natto, Bacillus subtilis subsp. natto, Bacillus subtilis var. natto
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