(48 nodes) Ubiquitin-dependent ERAD pathway network (Pyrenophora teres)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lcl2	Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. (129 aa)
	PTT_08985	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1073 aa)
	PTT_09456	HECT domain-containing protein. (1205 aa)
	PTT_09488	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (569 aa)
	PTT_09643	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
	PTT_09674	Plug_translocon domain-containing protein. (476 aa)
	PTT_09932	UBX domain-containing protein. (475 aa)
	PTT_17800	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (246 aa)
	PTT_17853	Uncharacterized protein. (864 aa)
	PTT_17906	Uncharacterized protein. (420 aa)
	PTT_18066	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (303 aa)
	PTT_18087	ATPase_AAA_core domain-containing protein. (531 aa)
	PTT_18162	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (511 aa)
	PTT_19077	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (441 aa)
	PTT_19350	RING-type domain-containing protein. (765 aa)
	PTT_19408	UBIQUITIN_CONJUGAT_2 domain-containing protein. (294 aa)
	PTT_19626	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (708 aa)
	PTT_19738	Uncharacterized protein. (185 aa)
	PTT_00527	AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
	PTT_04922	AAA domain-containing protein. (565 aa)
	PTT_15646	UBIQUITIN_CONJUGAT_2 domain-containing protein. (281 aa)
	PTT_15782	UBX domain-containing protein. (499 aa)
	PTT_15840	N-acetyltransferase domain-containing protein. (193 aa)
	PTT_15922	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (116 aa)
	PTT_15923	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (186 aa)
	PTT_16730	Uncharacterized protein. (357 aa)
	PTT_17197	TPR_REGION domain-containing protein. (387 aa)
	PTT_17225	Uncharacterized protein. (1694 aa)
	PTT_04968	Uncharacterized protein. (384 aa)
	PTT_05232	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (588 aa)
	PTT_07870	J domain-containing protein. (352 aa)
	PTT_07876	U-box domain-containing protein. (1114 aa)
	PTT_15056	AZUL domain-containing protein. (774 aa)
	PTT_14561	UBX domain-containing protein. (549 aa)
	PTT_13813	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (262 aa)
	PTT_13534	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (995 aa)
	PTT_13361	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (593 aa)
	PTT_13087	Uncharacterized protein; Belongs to the heat shock protein 70 family. (676 aa)
	PTT_12687	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (254 aa)
	PTT_12478	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (319 aa)
	PTT_12470	J domain-containing protein. (325 aa)
	PTT_12303	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (968 aa)
	PTT_12208	Uncharacterized protein; Belongs to the AAA ATPase family. (819 aa)
	PTT_08665	ANK_REP_REGION domain-containing protein. (643 aa)
	PTT_11598	Uncharacterized protein. (1531 aa)
	PTT_10843	PRKCSH domain-containing protein. (530 aa)
	PTT_10639	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (639 aa)
	PTT_10348	OTU domain-containing protein. (328 aa)

Your Current Organism:

Pyrenophora teres

NCBI taxonomy Id: 861557
Other names: P. teres f. teres 0-1, Pyrenophora teres f. teres 0-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTT_00527	PTT_04922	E3RCJ7	E3RER0	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein.	0.444
PTT_00527	PTT_04968	E3RCJ7	E3RET8	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.824
PTT_00527	PTT_12208	E3RCJ7	E3RT91	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.469
PTT_00527	PTT_15056	E3RCJ7	E3RZH8	AAA domain-containing protein; Belongs to the AAA ATPase family.	AZUL domain-containing protein.	0.606
PTT_00527	PTT_16730	E3RCJ7	E3S2X9	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.698
PTT_00527	PTT_17225	E3RCJ7	E3S3Y2	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.892
PTT_00527	PTT_18087	E3RCJ7	E3S5X7	AAA domain-containing protein; Belongs to the AAA ATPase family.	ATPase_AAA_core domain-containing protein.	0.444
PTT_04922	PTT_00527	E3RER0	E3RCJ7	AAA domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.444
PTT_04922	PTT_04968	E3RER0	E3RET8	AAA domain-containing protein.	Uncharacterized protein.	0.640
PTT_04922	PTT_07876	E3RER0	E3RIK3	AAA domain-containing protein.	U-box domain-containing protein.	0.799
PTT_04922	PTT_08665	E3RER0	E3RKB4	AAA domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.634
PTT_04922	PTT_09932	E3RER0	E3RN42	AAA domain-containing protein.	UBX domain-containing protein.	0.573
PTT_04922	PTT_10348	E3RER0	E3RP17	AAA domain-containing protein.	OTU domain-containing protein.	0.885
PTT_04922	PTT_10843	E3RER0	E3RQ79	AAA domain-containing protein.	PRKCSH domain-containing protein.	0.725
PTT_04922	PTT_11598	E3RER0	E3RRV9	AAA domain-containing protein.	Uncharacterized protein.	0.793
PTT_04922	PTT_12208	E3RER0	E3RT91	AAA domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.900
PTT_04922	PTT_12687	E3RER0	E3RUD5	AAA domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.870
PTT_04922	PTT_13087	E3RER0	E3RVA0	AAA domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.529
PTT_04922	PTT_13813	E3RER0	E3RWV9	AAA domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.886
PTT_04922	PTT_14561	E3RER0	E3RYE8	AAA domain-containing protein.	UBX domain-containing protein.	0.700