(52 nodes) Identical protein binding network (Pyrenophora teres)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTT_09712	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (484 aa)
	PTT_20368	Uncharacterized protein. (275 aa)
	PTT_20334	Uncharacterized protein. (685 aa)
	PTT_20301	RNA helicase. (808 aa)
	PTT_20059	Uncharacterized protein. (322 aa)
	PTT_19920	Uncharacterized protein. (607 aa)
	PTT_19437	EXPERA domain-containing protein. (239 aa)
	PTT_19434	Uncharacterized protein. (973 aa)
	PTT_19180	Uncharacterized protein. (1118 aa)
	PTT_19169	Uncharacterized protein. (519 aa)
	PTT_18869	Lactamase_B domain-containing protein. (333 aa)
	PTT_18719	Uncharacterized protein. (322 aa)
	PTT_18717	Uncharacterized protein. (428 aa)
	PTT_18069	Uncharacterized protein. (595 aa)
	PTT_17879	BTB domain-containing protein. (213 aa)
	PTT_17738	Uncharacterized protein. (259 aa)
	PTT_17176	NodB homology domain-containing protein. (329 aa)
	PTT_17173	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1053 aa)
	PTT_17080	3'-5' exonuclease domain-containing protein. (741 aa)
	PTT_16376	Uncharacterized protein. (740 aa)
	PTT_16297	SAE2 domain-containing protein. (776 aa)
	PTT_15669	Uncharacterized protein. (444 aa)
	PTT_15083	Uncharacterized protein. (154 aa)
	PTT_14783	Tyrosine--tRNA ligase. (611 aa)
	PTT_14457	Uncharacterized protein. (754 aa)
	PTT_14139	Ornithine aminotransferase. (501 aa)
	URM1	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (107 aa)
	PTT_13535	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (599 aa)
	PTT_13434	Uncharacterized protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (417 aa)
	PTT_13287	Response regulatory domain-containing protein. (626 aa)
	PTT_12502	NTP_transf_9 domain-containing protein. (252 aa)
	PTT_11482	Uncharacterized protein. (738 aa)
	PTT_11396	Uncharacterized protein. (2465 aa)
	PTT_11234	Uncharacterized protein. (1173 aa)
	PTT_10960	Epimerase domain-containing protein. (322 aa)
	PTT_10117	Uncharacterized protein. (222 aa)
	PTT_09778	Glucosamine-6-phosphate isomerase. (372 aa)
	PTT_09708	PAD domain-containing protein. (607 aa)
	PTT_09692	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (231 aa)
	PTT_09564	Uncharacterized protein. (764 aa)
	uba4	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (534 aa)
	PTT_08611	Uncharacterized protein. (183 aa)
	PTT_07973	Uncharacterized protein. (154 aa)
	PTT_07347	Uncharacterized protein. (442 aa)
	PTT_07018	BTB domain-containing protein. (264 aa)
	PTT_06636	Uncharacterized protein. (934 aa)
	PRT1	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (828 aa)
	PTT_06009	Uncharacterized protein. (192 aa)
	GET3	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (339 aa)
	PTT_04366	Uncharacterized protein. (225 aa)
	PTT_01399	Uncharacterized protein. (213 aa)
	PTT_00376	Uncharacterized protein. (396 aa)

Your Current Organism:

Pyrenophora teres

NCBI taxonomy Id: 861557
Other names: P. teres f. teres 0-1, Pyrenophora teres f. teres 0-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTT_00376	PTT_07347	E3RCF1	E3RHG0	Uncharacterized protein.	Uncharacterized protein.	0.998
PTT_00376	PTT_09564	E3RCF1	E3RMA4	Uncharacterized protein.	Uncharacterized protein.	0.850
PTT_00376	PTT_19180	E3RCF1	E3S8D5	Uncharacterized protein.	Uncharacterized protein.	0.850
PTT_00376	uba4	E3RCF1	E3RLG9	Uncharacterized protein.	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.728
PTT_01399	PTT_04366	E3RD09	E3REE7	Uncharacterized protein.	Uncharacterized protein.	0.947
PTT_04366	PTT_01399	E3REE7	E3RD09	Uncharacterized protein.	Uncharacterized protein.	0.947
PTT_06636	PTT_17080	E3RFV5	E3S3M1	Uncharacterized protein.	3'-5' exonuclease domain-containing protein.	0.986
PTT_07347	PTT_00376	E3RHG0	E3RCF1	Uncharacterized protein.	Uncharacterized protein.	0.998
PTT_07347	uba4	E3RHG0	E3RLG9	Uncharacterized protein.	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.560
PTT_09564	PTT_00376	E3RMA4	E3RCF1	Uncharacterized protein.	Uncharacterized protein.	0.850
PTT_09564	uba4	E3RMA4	E3RLG9	Uncharacterized protein.	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.424
PTT_09692	PTT_13535	E3RMK9	E3RWA6	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.825
PTT_10117	PTT_14457	E3RNH1	E3RY76	Uncharacterized protein.	Uncharacterized protein.	0.767
PTT_10960	PTT_13434	E3RQG7	E3RW37	Epimerase domain-containing protein.	Uncharacterized protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	0.570
PTT_10960	PTT_15669	E3RQG7	E3S0P9	Epimerase domain-containing protein.	Uncharacterized protein.	0.450
PTT_10960	PTT_18717	E3RQG7	E3S7C4	Epimerase domain-containing protein.	Uncharacterized protein.	0.450
PTT_10960	PTT_18719	E3RQG7	E3S7C6	Epimerase domain-containing protein.	Uncharacterized protein.	0.450
PTT_13434	PTT_10960	E3RW37	E3RQG7	Uncharacterized protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	Epimerase domain-containing protein.	0.570
PTT_13535	PTT_09692	E3RWA6	E3RMK9	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.825
PTT_14457	PTT_10117	E3RY76	E3RNH1	Uncharacterized protein.	Uncharacterized protein.	0.767