(59 nodes) Nucleic acid-binding, OB-fold network (Pyrenophora teres)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTT_11325	Telo_bind domain-containing protein. (1464 aa)
	PTT_11043	Telo_bind domain-containing protein. (598 aa)
	PTT_10522	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (145 aa)
	PTT_10390	S1-like domain-containing protein. (118 aa)
	PTT_04365	Uncharacterized protein. (144 aa)
	PTT_04001	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (146 aa)
	PTT_09951	Uncharacterized protein. (239 aa)
	PTT_09950	AA_TRNA_LIGASE_II domain-containing protein. (551 aa)
	PTT_09856	Uncharacterized protein. (211 aa)
	PTT_08703	AAA domain-containing protein; Belongs to the AAA ATPase family. (460 aa)
	PTT_08504	Eukaryotic translation initiation factor 5A. (163 aa)
	PTT_07805	AA_TRNA_LIGASE_II domain-containing protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (799 aa)
	PTT_07680	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (559 aa)
	PTT_07640	Uncharacterized protein. (107 aa)
	PTT_07229	AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
	PTT_00527	AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
	PTT_20305	Uncharacterized protein. (288 aa)
	PTT_19976	DNA helicase; Belongs to the MCM family. (857 aa)
	PTT_19961	Uncharacterized protein. (751 aa)
	PTT_19733	S1 motif domain-containing protein. (171 aa)
	PTT_19609	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (158 aa)
	PTT_18775	AA_TRNA_LIGASE_II domain-containing protein. (601 aa)
	PTT_18630	Ribosomal_L2_C domain-containing protein. (372 aa)
	PTT_18017	AA_TRNA_LIGASE_II domain-containing protein. (555 aa)
	PTT_17935	AA_TRNA_LIGASE_II domain-containing protein. (575 aa)
	PTT_17907	Uncharacterized protein. (214 aa)
	PTT_17801	AAA domain-containing protein; Belongs to the AAA ATPase family. (466 aa)
	PTT_17796	Uncharacterized protein. (151 aa)
	PTT_17759	Uncharacterized protein. (1214 aa)
	PTT_17758	DNA helicase; Belongs to the MCM family. (957 aa)
	PTT_17755	tRNA-binding domain-containing protein. (464 aa)
	PTT_17650	DNA ligase. (988 aa)
	PTT_17530	Uncharacterized protein; Belongs to the RNR ribonuclease family. (989 aa)
	PTT_17200	DNA ligase. (909 aa)
	PTT_17149	Ribosomal_L2_C domain-containing protein. (254 aa)
	PTT_16774	Uncharacterized protein. (68 aa)
	PTT_16651	DNA helicase; Belongs to the MCM family. (724 aa)
	PTT_16497	DNA helicase; Belongs to the MCM family. (1015 aa)
	PTT_16081	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (179 aa)
	PTT_15523	Stn1 domain-containing protein. (257 aa)
	PTT_15455	DNA_LIGASE_A3 domain-containing protein. (874 aa)
	PTT_15345	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (587 aa)
	PTT_14959	S1 motif domain-containing protein. (311 aa)
	PTT_14578	AAA domain-containing protein; Belongs to the AAA ATPase family. (389 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (812 aa)
	PTT_14414	Uncharacterized protein. (1791 aa)
	PTT_14301	Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (159 aa)
	PTT_14121	RNB domain-containing protein. (1049 aa)
	PTT_13732	AA_TRNA_LIGASE_II domain-containing protein. (633 aa)
	PTT_13602	RNB domain-containing protein. (1365 aa)
	PTT_13131	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1447 aa)
	PTT_12884	AAA domain-containing protein; Belongs to the AAA ATPase family. (421 aa)
	PTT_12262	S1 motif domain-containing protein. (214 aa)
	PTT_12153	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (423 aa)
	PTT_07150	DNA helicase; Belongs to the MCM family. (867 aa)
	PTT_04382	ECR1_N domain-containing protein. (348 aa)
	PTT_11927	AA_TRNA_LIGASE_II domain-containing protein. (1041 aa)
	PTT_11864	Zf-primase domain-containing protein. (802 aa)
	PTT_11577	DNA ligase. (873 aa)

Your Current Organism:

Pyrenophora teres

NCBI taxonomy Id: 861557
Other names: P. teres f. teres 0-1, Pyrenophora teres f. teres 0-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	PTT_07150	E3RYD4	E3RH10	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PTT_11577	E3RYD4	E3RRT9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.667
MCM7	PTT_11864	E3RYD4	E3RSH5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Zf-primase domain-containing protein.	0.995
MCM7	PTT_15345	E3RYD4	E3S010	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.739
MCM7	PTT_15455	E3RYD4	E3S087	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA_LIGASE_A3 domain-containing protein.	0.432
MCM7	PTT_16497	E3RYD4	E3S2H0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PTT_16651	E3RYD4	E3S2S8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PTT_17200	E3RYD4	E3S3V7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.729
MCM7	PTT_17650	E3RYD4	E3S4W2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA ligase.	0.432
MCM7	PTT_17758	E3RYD4	E3S582	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PTT_19976	E3RYD4	E3SA60	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PTT_20305	E3RYD4	E3SAT1	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.818
PTT_00527	PTT_07229	E3RCJ7	E3RH64	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
PTT_00527	PTT_08703	E3RCJ7	E3RKE6	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
PTT_00527	PTT_12884	E3RCJ7	E3RUU4	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
PTT_00527	PTT_14578	E3RCJ7	E3RYG4	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
PTT_00527	PTT_14959	E3RCJ7	E3RZA6	AAA domain-containing protein; Belongs to the AAA ATPase family.	S1 motif domain-containing protein.	0.453
PTT_00527	PTT_17801	E3RCJ7	E3S5A3	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
PTT_04001	PTT_09856	E3RE92	E3RMW1	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	Uncharacterized protein.	0.573
PTT_04001	PTT_11577	E3RE92	E3RRT9	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	DNA ligase.	0.523