(59 nodes) Winged helix DNA-binding domain superfamily network (Pyrenophora teres)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTT_01272	Methionine aminopeptidase 2-1; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (452 aa)
	PTT_01399	Uncharacterized protein. (213 aa)
	PTT_01727	Methionine aminopeptidase 2-2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (459 aa)
	PTT_02779	Uncharacterized protein. (645 aa)
	PTT_03616	PCI domain-containing protein. (417 aa)
	PTT_03617	Uncharacterized protein. (354 aa)
	PTT_03708	Uncharacterized protein. (281 aa)
	PTT_04315	Uncharacterized protein. (104 aa)
	PTT_04364	Uncharacterized protein. (1410 aa)
	PTT_04647	CULLIN_2 domain-containing protein; Belongs to the cullin family. (930 aa)
	PTT_04953	CULLIN_2 domain-containing protein; Belongs to the cullin family. (769 aa)
	PTT_06554	HSF_DOMAIN domain-containing protein. (593 aa)
	PTT_07451	RIO domain-containing protein. (440 aa)
	PTT_07867	Uncharacterized protein. (549 aa)
	PTT_07888	PCI domain-containing protein. (423 aa)
	PTT_07892	Methyltransf_2 domain-containing protein. (435 aa)
	PTT_08155	Uncharacterized protein. (2004 aa)
	PTT_08520	Methyltransf_2 domain-containing protein. (426 aa)
	PTT_09109	RFX-type winged-helix domain-containing protein. (816 aa)
	PTT_09237	Uncharacterized protein. (126 aa)
	PTT_09296	Uncharacterized protein. (1059 aa)
	PTT_09832	Uncharacterized protein. (658 aa)
	PTT_09874	H15 domain-containing protein. (265 aa)
	PTT_10197	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (639 aa)
	PTT_10226	GLUE N-terminal domain-containing protein. (595 aa)
	PTT_10297	PCI domain-containing protein. (485 aa)
	PTT_11399	HTH La-type RNA-binding domain-containing protein. (1025 aa)
	PTT_11771	Uncharacterized protein. (1276 aa)
	PTT_11909	Methyltransf_2 domain-containing protein. (403 aa)
	PTT_12214	Methyltransf_2 domain-containing protein. (447 aa)
	PTT_12369	CULLIN_2 domain-containing protein; Belongs to the cullin family. (879 aa)
	PTT_12532	Uncharacterized protein. (315 aa)
	PTT_13038	Uncharacterized protein. (868 aa)
	PTT_13160	Methyltransf_2 domain-containing protein. (434 aa)
	PTT_13287	Response regulatory domain-containing protein. (626 aa)
	PTT_13449	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (245 aa)
	PTT_13465	PCI domain-containing protein; Belongs to the eIF-3 subunit C family. (829 aa)
	PTT_13779	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (400 aa)
	PTT_14832	PCI domain-containing protein. (505 aa)
	PTT_14841	CULLIN_2 domain-containing protein; Belongs to the cullin family. (819 aa)
	PTT_15041	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2157 aa)
	PTT_15143	Uncharacterized protein. (2223 aa)
	PTT_15520	Uncharacterized protein. (1492 aa)
	PTT_15810	Methyltransf_2 domain-containing protein. (376 aa)
	PTT_15848	PCI domain-containing protein. (489 aa)
	PTT_16256	Fork-head domain-containing protein. (660 aa)
	PTT_16950	HSF_DOMAIN domain-containing protein. (773 aa)
	PTT_17303	Methyltransf_2 domain-containing protein. (450 aa)
	PTT_17472	PCI domain-containing protein. (383 aa)
	PTT_17557	PCI domain-containing protein. (495 aa)
	PTT_17737	HTH La-type RNA-binding domain-containing protein. (541 aa)
	PTT_17936	PHD-type domain-containing protein. (1740 aa)
	PTT_18153	Uncharacterized protein. (840 aa)
	PTT_18397	PCI domain-containing protein. (470 aa)
	INT6	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (433 aa)
	PTT_19376	DEP domain-containing protein. (1917 aa)
	PTT_19449	Fork-head domain-containing protein. (458 aa)
	PTT_19867	Uncharacterized protein. (433 aa)
	PTT_20305	Uncharacterized protein. (288 aa)

Your Current Organism:

Pyrenophora teres

NCBI taxonomy Id: 861557
Other names: P. teres f. teres 0-1, Pyrenophora teres f. teres 0-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
INT6	PTT_03616	E3S6R0	E3RE28	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	PCI domain-containing protein.	0.513
INT6	PTT_04315	E3S6R0	E3REC2	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Uncharacterized protein.	0.933
INT6	PTT_09237	E3S6R0	E3RLI9	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Uncharacterized protein.	0.933
INT6	PTT_10297	E3S6R0	E3RNX6	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	PCI domain-containing protein.	0.486
INT6	PTT_13449	E3S6R0	E3RW49	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.999
INT6	PTT_13465	E3S6R0	E3RW60	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	PCI domain-containing protein; Belongs to the eIF-3 subunit C family.	0.999
INT6	PTT_17557	E3S6R0	E3S4P3	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	PCI domain-containing protein.	0.811
PTT_01399	PTT_03708	E3RD09	E3RE55	Uncharacterized protein.	Uncharacterized protein.	0.999
PTT_01399	PTT_10226	E3RD09	E3RNR3	Uncharacterized protein.	GLUE N-terminal domain-containing protein.	0.999
PTT_02779	PTT_16256	E3RDR7	E3S1W7	Uncharacterized protein.	Fork-head domain-containing protein.	0.450
PTT_03616	INT6	E3RE28	E3S6R0	PCI domain-containing protein.	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.513
PTT_03616	PTT_04953	E3RE28	E3RES6	PCI domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.854
PTT_03616	PTT_10297	E3RE28	E3RNX6	PCI domain-containing protein.	PCI domain-containing protein.	0.637
PTT_03616	PTT_12369	E3RE28	E3RTL9	PCI domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.948
PTT_03616	PTT_14841	E3RE28	E3RZ02	PCI domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.862
PTT_03616	PTT_15848	E3RE28	E3S133	PCI domain-containing protein.	PCI domain-containing protein.	0.999
PTT_03616	PTT_17557	E3RE28	E3S4P3	PCI domain-containing protein.	PCI domain-containing protein.	0.735
PTT_03616	PTT_18397	E3RE28	E3S6M7	PCI domain-containing protein.	PCI domain-containing protein.	0.999
PTT_03708	PTT_01399	E3RE55	E3RD09	Uncharacterized protein.	Uncharacterized protein.	0.999
PTT_03708	PTT_10226	E3RE55	E3RNR3	Uncharacterized protein.	GLUE N-terminal domain-containing protein.	0.999