(22 nodes) Butanoate metabolism network (Pyrenophora teres)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTT_02289	DAO domain-containing protein. (406 aa)
	PTT_02799	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (541 aa)
	PTT_06674	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa)
	PTT_07039	Uncharacterized protein. (153 aa)
	PTT_07605	Acetolactate synthase. (690 aa)
	PTT_08052	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (524 aa)
	PTT_08653	Pyruvate carboxyltransferase domain-containing protein. (395 aa)
	PTT_08706	Uncharacterized protein. (245 aa)
	PTT_08712	Uncharacterized protein. (320 aa)
	PTT_09720	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (548 aa)
	PTT_10362	Uncharacterized protein. (518 aa)
	PTT_11058	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (488 aa)
	PTT_11734	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (433 aa)
	PTT_12115	AMP-binding domain-containing protein. (646 aa)
	PTT_12731	ACT domain-containing protein. (324 aa)
	PTT_13196	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
	PTT_13228	Succinate-semialdehyde dehydrogenase. (498 aa)
	PTT_13311	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
	PTT_13677	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (457 aa)
	PTT_14090	Aldedh domain-containing protein. (509 aa)
	PTT_17323	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (513 aa)
	PTT_19912	Uncharacterized protein. (697 aa)

Your Current Organism:

Pyrenophora teres

NCBI taxonomy Id: 861557
Other names: P. teres f. teres 0-1, Pyrenophora teres f. teres 0-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTT_02289	PTT_08052	E3RDH8	E3RIY7	DAO domain-containing protein.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.805
PTT_02289	PTT_09720	E3RDH8	E3RMN0	DAO domain-containing protein.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.805
PTT_02289	PTT_10362	E3RDH8	E3RP31	DAO domain-containing protein.	Uncharacterized protein.	0.805
PTT_02799	PTT_07039	E3RDR9	E3RGT7	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein.	0.409
PTT_02799	PTT_08653	E3RDR9	E3RKA5	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Pyruvate carboxyltransferase domain-containing protein.	0.937
PTT_02799	PTT_08706	E3RDR9	E3RKE9	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein.	0.409
PTT_02799	PTT_08712	E3RDR9	E3RKF5	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein.	0.917
PTT_02799	PTT_11734	E3RDR9	E3RS82	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.940
PTT_02799	PTT_12115	E3RDR9	E3RT12	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	AMP-binding domain-containing protein.	0.913
PTT_02799	PTT_13196	E3RDR9	E3RVJ9	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.940
PTT_02799	PTT_13311	E3RDR9	E3RVT0	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.903
PTT_02799	PTT_13677	E3RDR9	E3RWK1	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.923
PTT_02799	PTT_17323	E3RDR9	E3S469	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.903
PTT_02799	PTT_19912	E3RDR9	E3SA01	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein.	0.913
PTT_06674	PTT_08052	E3RFY9	E3RIY7	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.961
PTT_06674	PTT_09720	E3RFY9	E3RMN0	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.961
PTT_06674	PTT_10362	E3RFY9	E3RP31	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Uncharacterized protein.	0.958
PTT_06674	PTT_11058	E3RFY9	E3RQP1	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.913
PTT_06674	PTT_13228	E3RFY9	E3RVL1	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Succinate-semialdehyde dehydrogenase.	0.984
PTT_06674	PTT_14090	E3RFY9	E3RXH4	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aldedh domain-containing protein.	0.954