STRINGSTRING
fumB fumB ppdK ppdK prs prs tktA tktA rpiB rpiB gap gap pfp pfp pgm pgm maeB maeB ach ach EFM02661.1 EFM02661.1 mutB mutB mutA mutA pgk pgk mmdB mmdB mmdC mmdC fbp fbp pyk pyk EFM02147.1 EFM02147.1 porA porA EFM02115.1 EFM02115.1 EFM02029.1 EFM02029.1 pfkA pfkA EFM02062.1 EFM02062.1 lctP lctP pgi pgi aspA aspA nifJ nifJ pmi pmi gatD gatD rpe rpe glmS glmS EFM01495.1 EFM01495.1 eno eno pta pta ackA ackA frdB frdB sdhA sdhA deoC deoC gpm gpm fumB2 fumB2 ttdA ttdA porG porG EFM01325.1 EFM01325.1 vorB vorB oorD oorD fba fba glk glk gloA gloA EFM01266.1 EFM01266.1 EFM01267.1 EFM01267.1 EFM01269.1 EFM01269.1 acsA acsA glyS glyS mip mip ansB ansB EFM01177.1 EFM01177.1 EFM01178.1 EFM01178.1 EFM01179.1 EFM01179.1 EFM01180.1 EFM01180.1 tpiA tpiA pckA pckA mce mce mmdA mmdA EFM00937.1 EFM00937.1 mmdC2 mmdC2 EFM00939.1 EFM00939.1 mdh mdh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fumBHydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (549 aa)
ppdKPyruvate, phosphate dikinase; COG: COG0574; Pfam: PF01326,PF00391,PF02896; InterPro: IPR010121; Belongs to the PEP-utilizing enzyme family. (907 aa)
prsRibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa)
tktATransketolase, thiamine diphosphate binding domain protein; COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478; Belongs to the transketolase family. (672 aa)
rpiBSugar-phosphate isomerase, RpiB/LacA/LacB family; COG: COG0698; Pfam: PF02502; InterPro: IPR003500. (149 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (546 aa)
pgmPhosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880; InterPro: IPR016055. (582 aa)
maeBMalate dehydrogenase (oxaloacetate-decarboxylating); COG: COG0281; Pfam: PF00390,PF03949,PF01515; InterPro: IPR002505. (729 aa)
achSuccinate CoA transferase; COG: COG0427; Pfam: PF02550; InterPro: IPR003702. (502 aa)
EFM02661.1Kinase, PfkB family; COG: COG0524; Pfam: PF00294; InterPro: IPR011611. (300 aa)
mutBmethylmalonyl-CoA mutase; COG: COG1884; Pfam: PF01642,PF02310; InterPro: IPR006098. (714 aa)
mutAmethylmalonyl-CoA mutase, small subunit; COG: COG1884; Pfam: PF01642; InterPro: IPR004608. (618 aa)
pgkPhosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. (416 aa)
mmdBSodium ion-translocating decarboxylase, beta subunit; COG: COG1883; Pfam: PF03977; InterPro: IPR005661. (385 aa)
mmdCBiotin-requiring enzyme; COG: COG0511; Pfam: PF00364; InterPro: IPR000089. (149 aa)
fbpFirmicute fructose-1,6-bisphosphatase; COG: COG3855; Pfam: PF06874; InterPro: IPR009164. (660 aa)
pykPyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family. (482 aa)
EFM02147.1Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; COG: COG1013; Pfam: PF02775; InterPro: IPR011766. (334 aa)
porA2-oxoacid:acceptor oxidoreductase, alpha subunit; COG: COG0674; Pfam: PF01558,PF01855; InterPro: IPR002880. (616 aa)
EFM02115.1LAO/AO transport system ATPase; COG: COG1703; Pfam: PF03308; InterPro: IPR005129. (369 aa)
EFM02029.1Hypothetical protein. (359 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)
EFM02062.1HMGL-like protein; COG: COG5016; Pfam: PF00682; InterPro: IPR013785. (590 aa)
lctPTransporter, lactate permease (LctP) family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (515 aa)
pgiGlucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. (452 aa)
aspAAspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. (468 aa)
nifJPyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. (1190 aa)
pmiPutative mannose-6-phosphate isomerase, class I; COG: COG1482; Pfam: PF01238; InterPro: IPR014710. (320 aa)
gatDPutative chlorophyll synthesis pathway protein BchC; COG: COG1063; Pfam: PF08240,PF00107; InterPro: IPR002085. (348 aa)
rpePutative ribulose-phosphate 3-epimerase; COG: COG0036; Pfam: PF00834; InterPro: IPR013785. (225 aa)
glmSGlutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (616 aa)
EFM01495.1biotin--[acetyl-CoA-carboxylase] ligase; COG: COG0340; Pfam: PF03099; InterPro: IPR004408. (248 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
ptaPhosphate acetyltransferase; COG: COG0280; Pfam: PF01515; InterPro: IPR002505. (357 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
frdBSuccinate dehydrogenase/fumarate reductase iron-sulfur subunit; InterPro: IPR012675. (253 aa)
sdhASuccinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG: COG1053; Pfam: PF00890,PF02910; InterPro: IPR011280. (648 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (313 aa)
gpmPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (229 aa)
fumB2Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; COG: COG1838; Pfam: PF05683; InterPro: IPR004647. (184 aa)
ttdAHydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; COG: COG1951; Pfam: PF05681; InterPro: IPR004646. (280 aa)
porG2-oxoacid:ferredoxin/flavodoxin oxidoreductase, gamma subunit; COG: COG1014; Pfam: PF01558; InterPro: IPR002869. (188 aa)
EFM01325.1Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; COG: COG1013; Pfam: PF02775; InterPro: IPR011766. (256 aa)
vorBPyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF02780; InterPro: IPR002880. (362 aa)
oorD4Fe-4S binding domain protein; Pfam: PF00037. (77 aa)
fbaFructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. (336 aa)
glkROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. (325 aa)
gloAGlyoxalase family protein; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. (128 aa)
EFM01266.1Hypothetical protein. (183 aa)
EFM01267.1Hypothetical protein. (159 aa)
EFM01269.1Cupin domain protein; COG: COG1396; Pfam: PF01381,PF07883; InterPro: IPR014710. (184 aa)
acsAAMP-binding enzyme; COG: COG0365; Pfam: PF00501; InterPro: IPR000873. (552 aa)
glySglycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (585 aa)
mipPeptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG0545; Pfam: PF00254; InterPro: IPR001179. (215 aa)
ansBL-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. (348 aa)
EFM01177.1Hypothetical protein. (39 aa)
EFM01178.1Cysteine-rich domain protein; COG: COG0247; Pfam: PF02754; InterPro: IPR004017. (245 aa)
EFM01179.1Putative iron-sulfur cluster-binding protein; COG: COG1139; Pfam: PF02589,PF00037; InterPro: IPR012285. (457 aa)
EFM01180.1Hypothetical protein; Pfam: PF02589; InterPro: IPR003741. (199 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa)
mcemethylmalonyl-CoA epimerase; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. (134 aa)
mmdACarboxyl transferase domain protein; COG: COG4799; Pfam: PF01039; InterPro: IPR000022. (517 aa)
EFM00937.1Hypothetical protein. (52 aa)
mmdC2Biotin-requiring enzyme; COG: COG0511; Pfam: PF00364; InterPro: IPR000089. (144 aa)
EFM00939.1Hypothetical protein. (40 aa)
mdhLactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Pfam: PF00056,PF02866; InterPro: IPR015955; Belongs to the LDH/MDH superfamily. (330 aa)
Your Current Organism:
Prevotella marshii
NCBI taxonomy Id: 862515
Other names: P. marshii DSM 16973 = JCM 13450, Prevotella marshii DSM 16973, Prevotella marshii DSM 16973 = DSM 16973, Prevotella marshii DSM 16973 = JCM 13450, Prevotella marshii E9.34, Prevotella marshii JCM 13450
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