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| | serS | serine--tRNA ligase; COG: COG0172; Pfam: PF02403,PF00587; InterPro: IPR002317. (429 aa) |
| | vicX | Metallo-beta-lactamase domain protein; COG: COG1235; Pfam: PF00753; InterPro: IPR001279. (267 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) |
| | fabF | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (420 aa) |
| | leuS | leucine--tRNA ligase; COG: COG0495; Pfam: PF09334,PF00133,PF08264; InterPro: IPR002302; Belongs to the class-I aminoacyl-tRNA synthetase family. (958 aa) |
| | argR | Arginine repressor, C-terminal domain protein; Regulates arginine biosynthesis genes. (162 aa) |
| | pdxT | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (189 aa) |
| | valS | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (879 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa) |
| | pyrB | Aspartate carbamoyltransferase; COG: COG0540; Pfam: PF02729,PF00185; InterPro: IPR002082; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (315 aa) |
| | nodN | MaoC-like protein; COG: COG2030; Pfam: PF01575; InterPro: IPR002539. (154 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (387 aa) |
| | ppdK | Pyruvate, phosphate dikinase; COG: COG0574; Pfam: PF01326,PF00391,PF02896; InterPro: IPR010121; Belongs to the PEP-utilizing enzyme family. (907 aa) |
| | fabHA | Beta-ketoacyl-acyl-carrier-protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (338 aa) |
| | tyrS | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (432 aa) |
| | pheS | phenylalanine--tRNA ligase, alpha subunit; COG: COG0016; Pfam: PF02912,PF01409; InterPro: IPR004529; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (383 aa) |
| | hisC | Putative histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR004839. (370 aa) |
| | asnS | asparagine--tRNA ligase; COG: COG0017; Pfam: PF01336,PF00152; InterPro: IPR004522. (467 aa) |
| | pfp | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (546 aa) |
| | ispE | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (279 aa) |
| | glnS | glutamine--tRNA ligase; COG: COG0008; Pfam: PF00749,PF03950; InterPro: IPR000924. (573 aa) |
| | coaBC | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (401 aa) |
| | maeB | Malate dehydrogenase (oxaloacetate-decarboxylating); COG: COG0281; Pfam: PF00390,PF03949,PF01515; InterPro: IPR002505. (729 aa) |
| | ach | Succinate CoA transferase; COG: COG0427; Pfam: PF02550; InterPro: IPR003702. (502 aa) |
| | EFM02699.1 | Hypothetical protein. (123 aa) |
| | fabF2 | Beta-ketoacyl synthase, C-terminal domain protein; COG: COG0304; Pfam: PF00109,PF02801; InterPro: IPR016038; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (577 aa) |
| | acpP2 | Putative acyl carrier protein; COG: COG0236. (85 aa) |
| | fabF3 | Beta-ketoacyl synthase, C-terminal domain protein; COG: COG0304; Pfam: PF00109,PF02801; InterPro: IPR016038; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (571 aa) |
| | acpP-2 | Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (81 aa) |
| | fabF4 | Beta-ketoacyl synthase, C-terminal domain protein; COG: COG0304; Pfam: PF00109,PF02801; InterPro: IPR000794; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (404 aa) |
| | fabG | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. (242 aa) |
| | hutH | Phenylalanine and histidine ammonia-lyase; COG: COG2986; Pfam: PF00221; InterPro: IPR001106. (504 aa) |
| | EFM02664.1 | Radical SAM domain protein; Pfam: PF04055; InterPro: IPR007197. (355 aa) |
| | EFM02665.1 | Oxidoreductase, NAD-binding domain protein; Pfam: PF01408; InterPro: IPR016040. (354 aa) |
| | fabD | [acyl-carrier-protein] S-malonyltransferase; COG: COG0331; Pfam: PF00698; InterPro: IPR001227. (298 aa) |
| | ugd | Nucleotide sugar dehydrogenase; COG: COG1004; Pfam: PF03721,PF00984,PF03720; InterPro: IPR014028. (438 aa) |
| | hisS | histidine--tRNA ligase; COG: COG0124; Pfam: PF00587,PF03129; InterPro: IPR015807. (452 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; COG: COG0801; Pfam: PF01288; InterPro: IPR000550. (136 aa) |
| | mutA | methylmalonyl-CoA mutase, small subunit; COG: COG1884; Pfam: PF01642; InterPro: IPR004608. (618 aa) |
| | carA | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. (358 aa) |
| | purF | Class II glutamine amidotransferase; COG: COG0034; Pfam: PF00310; InterPro: IPR005854. (628 aa) |
| | fabH2 | 3-oxoacyl-(acyl carrier protein) synthase III. (87 aa) |
| | EFM02514.1 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. (587 aa) |
| | pgk | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. (416 aa) |
| | pheB | Putative 3-deoxy-7-phosphoheptulonate synthase; COG: COG2876; Pfam: PF00793,PF01817; InterPro: IPR013785. (362 aa) |
| | mmdC | Biotin-requiring enzyme; COG: COG0511; Pfam: PF00364; InterPro: IPR000089. (149 aa) |
| | aroE | Putative shikimate dehydrogenase; COG: COG0169; Pfam: PF08501,PF01488; InterPro: IPR016040. (248 aa) |
| | ilvE | Branched-chain-amino-acid transaminase; COG: COG0115; Pfam: PF01063; InterPro: IPR001544. (340 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa) |
| | fabH3 | Putative 3-oxoacyl-(acyl carrier protein) synthase III. (214 aa) |
| | EFM02380.1 | 3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal domain protein; Pfam: PF08541. (161 aa) |
| | lysC | Amino acid kinase family; COG: COG0527; Pfam: PF00696; InterPro: IPR001341; Belongs to the aspartokinase family. (438 aa) |
| | pyk | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family. (482 aa) |
| | fabG-2 | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa) |
| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (126 aa) |
| | lipB | Metallo-beta-lactamase domain protein; COG: COG1235; Pfam: PF00753; InterPro: IPR001279. (254 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (355 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (535 aa) |
| | thrS | threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (654 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (824 aa) |
| | EFM02212.1 | Acyl-ACP thioesterase; Pfam: PF01643; InterPro: IPR002864. (256 aa) |
| | metG | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (681 aa) |
| | EFM02229.1 | Hypothetical protein. (556 aa) |
| | folA | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (160 aa) |
| | metH | Homocysteine S-methyltransferase; COG: COG0646; Pfam: PF02574; InterPro: IPR003726. (351 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (287 aa) |
| | aroB | Putative 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (353 aa) |
| | EFM02089.1 | Hypothetical protein; InterPro: IPR001544. (205 aa) |
| | EFM01998.1 | Hypothetical protein. (585 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (464 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1143 aa) |
| | EFM02029.1 | Hypothetical protein. (359 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa) |
| | aspS | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (589 aa) |
| | gltA | Putative glutamate synthase (NADPH), homotetrameric; COG: COG0493; Pfam: PF07992,PF00070; InterPro: IPR013027. (475 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa) |
| | EFM01908.1 | Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753; InterPro: IPR001279. (214 aa) |
| | pgi | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. (452 aa) |
| | lysS | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. (576 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (241 aa) |
| | yddR | Metallo-beta-lactamase domain protein; COG: COG2220; Pfam: PF00753; InterPro: IPR001279. (254 aa) |
| | cysE | Putative serine O-acetyltransferase; COG: COG1045; Pfam: PF00132. (299 aa) |
| | EFM01757.1 | Hypothetical protein; COG: COG0623; InterPro: IPR014358; 1.3.1.9. (292 aa) |
| | cysS | cysteine--tRNA ligase; COG: COG0215; Pfam: PF01406,PF09190; InterPro: IPR002308; Belongs to the class-I aminoacyl-tRNA synthetase family. (499 aa) |
| | hutI | Imidazolonepropionase; COG: COG1228; Pfam: PF01979; InterPro: IPR005920. (415 aa) |
| | hutH-2 | Histidine ammonia-lyase; COG: COG2986; Pfam: PF00221; InterPro: IPR005921. (491 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (664 aa) |
| | ftcD | Glutamate formimidoyltransferase; COG: COG3643; Pfam: PF07837,PF02971,PF04961; InterPro: IPR004227. (567 aa) |
| | trpF | N-(5'phosphoribosyl)anthranilate isomerase; Pfam: PF00697; InterPro: IPR013785; Belongs to the TrpF family. (235 aa) |
| | cicA | HAD phosphoserine phosphatase-like hydrolase, family IB; InterPro: IPR006383. (199 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (165 aa) |
| | fahA | FAH family protein; COG: COG0179; Pfam: PF01557; InterPro: IPR011234. (205 aa) |
| | EFM01675.1 | Hypothetical protein; 2.3.1.30. (53 aa) |
| | ispD-2 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (263 aa) |
| | gatD | Putative chlorophyll synthesis pathway protein BchC; COG: COG1063; Pfam: PF08240,PF00107; InterPro: IPR002085. (348 aa) |
| | EFM01606.1 | MaoC-like protein; Pfam: PF01575. (140 aa) |
| | fabG3 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. (245 aa) |
| | EFM01610.1 | Hypothetical protein. (83 aa) |
| | EFM01624.1 | Bacterial transferase hexapeptide repeat protein; COG: COG1045; Pfam: PF00132. (210 aa) |
| | glmS | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (616 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (620 aa) |
| | acp | Putative acyl carrier protein; InterPro: IPR009081. (85 aa) |
| | EFM01398.1 | MBOAT family protein; COG: COG1696; Pfam: PF03062; InterPro: IPR004299; Belongs to the membrane-bound acyltransferase family. (456 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (251 aa) |
| | trpS | tryptophan--tRNA ligase; COG: COG0180; Pfam: PF00579; InterPro: IPR002306; Belongs to the class-I aminoacyl-tRNA synthetase family. (329 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (304 aa) |
| | kbl | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (426 aa) |
| | speA | Arginine 2-monooxygenase; Catalyzes the biosynthesis of agmatine from arginine. (630 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (175 aa) |
| | pdxT-2 | Renal dipeptidase family protein; COG: COG2071; Pfam: PF07722,PF01244; InterPro: IPR008257. (589 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa) |
| | fadD | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. (602 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (505 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (150 aa) |
| | gpm | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (229 aa) |
| | EFM01568.1 | Putative histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR015421. (346 aa) |
| | EFM01316.1 | Hypothetical protein. (314 aa) |
| | EFM01319.1 | Methylaspartate ammonia-lyase; COG: COG3799; Pfam: PF05034,PF07476; InterPro: IPR006395. (412 aa) |
| | glmE | Methylaspartate mutase, E subunit; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (487 aa) |
| | folD | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa) |
| | sufS | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (405 aa) |
| | purL | Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1246 aa) |
| | EFM01245.1 | Peptidase dimerization domain protein; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. (471 aa) |
| | fba | Fructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. (336 aa) |
| | glsA | COG: COG2066; Pfam: PF04960; InterPro: IPR007043; Belongs to the glutaminase family. (304 aa) |
| | acsA | AMP-binding enzyme; COG: COG0365; Pfam: PF00501; InterPro: IPR000873. (552 aa) |
| | glyS | glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (585 aa) |
| | ansB | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. (348 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. (514 aa) |
| | alaS | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (875 aa) |
| | mtnN | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (251 aa) |
| | EFM01161.1 | Hypothetical protein; COG: COG3681; Pfam: PF06354; InterPro: IPR010469; Belongs to the UPF0597 family. (430 aa) |
| | EFM01179.1 | Putative iron-sulfur cluster-binding protein; COG: COG1139; Pfam: PF02589,PF00037; InterPro: IPR012285. (457 aa) |
| | EFM01180.1 | Hypothetical protein; Pfam: PF02589; InterPro: IPR003741. (199 aa) |
| | pheT | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Pfam: PF01588,PF03483,PF03484,PF03147; InterPro: IPR004532; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (821 aa) |
| | EFM01054.1 | Hypothetical protein. (567 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa) |
| | nrfA | Nitrite reductase; COG: COG3303; Pfam: PF02335; InterPro: IPR003321; Belongs to the cytochrome c-552 family. (495 aa) |
| | aroA | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (416 aa) |
| | glnA | Glutamine synthetase, beta-grasp domain protein; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. (501 aa) |
| | cysK | Cysteine synthase A; COG: COG0031; Pfam: PF00291; InterPro: IPR005859; Belongs to the cysteine synthase/cystathionine beta- synthase family. (317 aa) |
| | gcvT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (363 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (440 aa) |
| | gcvPB | Putative glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (488 aa) |
| | argS | arginine--tRNA ligase; COG: COG0018; Pfam: PF03485,PF00750,PF05746; InterPro: IPR001278. (604 aa) |
| | glxK | Glycerate kinase; COG: COG1929; Pfam: PF02595; InterPro: IPR004381; Belongs to the glycerate kinase type-1 family. (355 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) |
| | gdh | Glutamate dehydrogenase, NAD-specific; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (483 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (359 aa) |
| | mce | methylmalonyl-CoA epimerase; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. (134 aa) |
| | mmdA | Carboxyl transferase domain protein; COG: COG4799; Pfam: PF01039; InterPro: IPR000022. (517 aa) |
| | mmdC2 | Biotin-requiring enzyme; COG: COG0511; Pfam: PF00364; InterPro: IPR000089. (144 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (115 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa) |
| | EFM00795.1 | Putative o-succinylbenzoate synthase; Pfam: PF01188; InterPro: IPR001354. (346 aa) |
| | folK2 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; InterPro: IPR000550. (131 aa) |
| | proS | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (493 aa) |
| | mdh | Lactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Pfam: PF00056,PF02866; InterPro: IPR015955; Belongs to the LDH/MDH superfamily. (330 aa) |
