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fba fba mdh mdh acsA acsA pdxB pdxB glyA glyA fbp fbp serC serC pdxB-2 pdxB-2 EFM02020.1 EFM02020.1 pfkA pfkA eno eno pta pta ackA ackA gpm gpm
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbaFructose-1,6-bisphosphate aldolase, class II; COG: COG0191; Pfam: PF01116; InterPro: IPR000771. (336 aa)
mdhLactate/malate dehydrogenase, NAD binding domain protein; COG: COG0039; Pfam: PF00056,PF02866; InterPro: IPR015955; Belongs to the LDH/MDH superfamily. (330 aa)
acsAAMP-binding enzyme; COG: COG0365; Pfam: PF00501; InterPro: IPR000873. (552 aa)
pdxB4-phosphoerythronate dehydrogenase; COG: COG1052; Pfam: PF00389,PF02826; InterPro: IPR006139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa)
fbpFirmicute fructose-1,6-bisphosphatase; COG: COG3855; Pfam: PF06874; InterPro: IPR009164. (660 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (355 aa)
pdxB-24-phosphoerythronate dehydrogenase; COG: COG0111; Pfam: PF00389,PF02826; InterPro: IPR006139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (305 aa)
EFM02020.1Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. (225 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
ptaPhosphate acetyltransferase; COG: COG0280; Pfam: PF01515; InterPro: IPR002505. (357 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
gpmPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (229 aa)
Your Current Organism:
Prevotella marshii
NCBI taxonomy Id: 862515
Other names: P. marshii DSM 16973 = JCM 13450, Prevotella marshii DSM 16973, Prevotella marshii DSM 16973 = DSM 16973, Prevotella marshii DSM 16973 = JCM 13450, Prevotella marshii E9.34, Prevotella marshii JCM 13450
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