STRINGSTRING
AEN08222.1 AEN08222.1 AEN08223.1 AEN08223.1 AEN08224.1 AEN08224.1 AEN08225.1 AEN08225.1 AEN08226.1 AEN08226.1 AEN08227.1 AEN08227.1 AEN08228.1 AEN08228.1 AEN08230.1 AEN08230.1 AEN08231.1 AEN08231.1 AEN08232.1 AEN08232.1 AEN08352.1 AEN08352.1 AEN08445.1 AEN08445.1 ureD ureD ureG ureG ureF ureF ureC ureC ureB ureB ureA ureA AEN08586.1 AEN08586.1 AEN08587.1 AEN08587.1 AEN08588.1 AEN08588.1 AEN08775.1 AEN08775.1 AEN09305.1 AEN09305.1 AEN09306.1 AEN09306.1 ureD-2 ureD-2 ureG-2 ureG-2 ureF-2 ureF-2 ureC-2 ureC-2 AEN09311.1 AEN09311.1 AEN09312.1 AEN09312.1 AEN09313.1 AEN09313.1 AEN09314.1 AEN09314.1 crcB crcB crcB-2 crcB-2 AEN09317.1 AEN09317.1 alc alc AEN10308.1 AEN10308.1 AEN10309.1 AEN10309.1 AEN10310.1 AEN10310.1 AEN11377.1 AEN11377.1 AEN11378.1 AEN11378.1 AEN11379.1 AEN11379.1 AEN11380.1 AEN11380.1 AEN11381.1 AEN11381.1 AEN11945.1 AEN11945.1 AEN13211.1 AEN13211.1 AEN13212.1 AEN13212.1 AEN13213.1 AEN13213.1 AEN13214.1 AEN13214.1 AEN13215.1 AEN13215.1 AEN13217.1 AEN13217.1 AEN13219.1 AEN13219.1 AEN13220.1 AEN13220.1 ureC-3 ureC-3 AEN13222.1 AEN13222.1 ureG-3 ureG-3 ureD-3 ureD-3 AEN13249.1 AEN13249.1 AEN13250.1 AEN13250.1 AEN13251.1 AEN13251.1 AEN13252.1 AEN13252.1 AEN13256.1 AEN13256.1 AEN13257.1 AEN13257.1 AEN13258.1 AEN13258.1 AEN13259.1 AEN13259.1 AEN13260.1 AEN13260.1 AEN13261.1 AEN13261.1 AEN13262.1 AEN13262.1 AEN13263.1 AEN13263.1 AEN13264.1 AEN13264.1 AEN13282.1 AEN13282.1 AEN13283.1 AEN13283.1 AEN13289.1 AEN13289.1 crcB-3 crcB-3 crcB-4 crcB-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEN08222.1PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: sgr:SGR_6760 putative oxidoreductase. (696 aa)
AEN08223.1PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: sgr:SGR_6759 putative oxidoreductase molybdopterin-binding subunit. (332 aa)
AEN08224.1PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: sgr:SGR_6758 putative oxidoreductase iron-sulphur-binding subunit. (190 aa)
AEN08225.1KEGG: sgr:SGR_6757 hypothetical protein. (131 aa)
AEN08226.1PFAM: Polysulphide reductase NrfD; KEGG: sen:SACE_3564 polysulphide reductase, NrfD. (305 aa)
AEN08227.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mmi:MMAR_5196 Fe-S-cluster-containing hydrogenase, HybA. (302 aa)
AEN08228.1TIGRFAM: formate dehydrogenase, alpha subunit; KEGG: sro:Sros_3728 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1093 aa)
AEN08230.1KEGG: sgr:SGR_6756 hypothetical protein. (115 aa)
AEN08231.1KEGG: sma:SAV_7464 transport protein; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein. (304 aa)
AEN08232.1PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sgr:SGR_6755 hypothetical protein. (269 aa)
AEN08352.1PFAM: protein of unknown function DUF182; KEGG: fre:Franean1_6196 hypothetical protein. (361 aa)
AEN08445.1KEGG: sgr:SGR_6525 hypothetical protein; Belongs to the HpcH/HpaI aldolase family. (432 aa)
ureDUrease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (254 aa)
ureGUrease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (225 aa)
ureFPutative urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (221 aa)
ureCTIGRFAM: urease, alpha subunit; KEGG: sgr:SGR_6297 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein. (573 aa)
ureBTIGRFAM: urease, beta subunit; KEGG: sma:SAV_7105 urease subunit beta; PFAM: Urease beta subunit; Belongs to the urease beta subunit family. (103 aa)
ureATIGRFAM: urease, gamma subunit; KEGG: sma:SAV_7104 urease subunit gamma; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family. (100 aa)
AEN08586.1PFAM: regulatory protein TetR; KEGG: sgr:SGR_6294 TetR family transcriptional regulator. (206 aa)
AEN08587.1KEGG: sgr:SGR_6293 putative integral membrane protein. (336 aa)
AEN08588.1KEGG: sgr:SGR_6290 hypothetical protein. (102 aa)
AEN08775.1PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: sma:SAV_7229 glutathione-independent formaldehyde dehydrogenase. (387 aa)
AEN09305.1KEGG: sgr:SGR_5550 hypothetical protein. (218 aa)
AEN09306.1KEGG: sgr:SGR_842 putative ammonium transporter; TIGRFAM: ammonium transporter; PFAM: ammonium transporter. (451 aa)
ureD-2Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (321 aa)
ureG-2Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (206 aa)
ureF-2Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (251 aa)
ureC-2TIGRFAM: urease, alpha subunit; KEGG: sgr:SGR_846 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein. (574 aa)
AEN09311.1TIGRFAM: urease, beta subunit; KEGG: sgr:SGR_847 putative urease beta subunit; PFAM: Urease beta subunit. (158 aa)
AEN09312.1KEGG: sgr:SGR_848 hypothetical protein. (269 aa)
AEN09313.1TIGRFAM: urease, gamma subunit; KEGG: sgr:SGR_849 putative urease gamma subunit; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family. (101 aa)
AEN09314.1PFAM: Urea transporter; KEGG: sgr:SGR_850 putative UreA transporter. (320 aa)
crcBCamphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (155 aa)
crcB-2Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (124 aa)
AEN09317.1KEGG: msm:MSMEG_1434 hypothetical protein. (125 aa)
alcTIGRFAM: allantoicase; KEGG: sgr:SGR_4882 allantoicase; PFAM: Allantoicase region; Belongs to the allantoicase family. (382 aa)
AEN10308.1PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: sgr:SGR_4594 putative oxidoreductase. (777 aa)
AEN10309.1PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: sgr:SGR_4593 hypothetical protein. (634 aa)
AEN10310.1PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: sgr:SGR_4592 putative oxidoreductase. (287 aa)
AEN11377.1PFAM: metallophosphoesterase; KEGG: sgr:SGR_3887 hypothetical protein. (519 aa)
AEN11378.1PFAM: protein of unknown function DUF1025; KEGG: sma:SAV_4125 hypothetical protein. (114 aa)
AEN11379.1KEGG: sgr:SGR_3891 hypothetical protein. (186 aa)
AEN11380.1DEAD/DEAH box helicase domain protein; KEGG: sgr:SGR_3892 putative ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. (790 aa)
AEN11381.1PFAM: amino acid permease-associated region; KEGG: sco:SCO4097 amino acid/metabolite permease. (522 aa)
AEN11945.1PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; KEGG: sgr:SGR_2686 putative OHCU decarboxylase. (248 aa)
AEN13211.1KEGG: sgr:SGR_1357 hypothetical protein. (265 aa)
AEN13212.1Transcriptional regulator, PucR family; PFAM: purine catabolism PurC domain protein; KEGG: sgr:SGR_1356 putative regulatory protein. (618 aa)
AEN13213.1PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: sgr:SGR_1355 putative oxidoreductase. (296 aa)
AEN13214.1PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: sgr:SGR_1354 putative oxidoreductase. (198 aa)
AEN13215.1PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: sgr:SGR_1353 putative xanthine dehydrogenase. (807 aa)
AEN13217.1PFAM: protein of unknown function DUF182; KEGG: sgr:SGR_1351 hypothetical protein. (379 aa)
AEN13219.1TIGRFAM: urease, gamma subunit; KEGG: sgr:SGR_238 putative urease gamma subunit; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family. (100 aa)
AEN13220.1TIGRFAM: urease, beta subunit; KEGG: sgr:SGR_237 putative urease beta subunit; PFAM: Urease beta subunit. (113 aa)
ureC-3TIGRFAM: urease, alpha subunit; KEGG: sgr:SGR_236 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein. (567 aa)
AEN13222.1KEGG: sgr:SGR_235 putative urease accessory protein. (221 aa)
ureG-3Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (238 aa)
ureD-3Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (250 aa)
AEN13249.1KEGG: sgr:SGR_1332 hypothetical protein. (73 aa)
AEN13250.1PFAM: GCN5-related N-acetyltransferase; KEGG: sgr:SGR_1331 putative acetyltransferase. (175 aa)
AEN13251.1KEGG: sgr:SGR_1330 hypothetical protein. (237 aa)
AEN13252.1KEGG: sgr:SGR_1329 glyoxylate carboligase; TIGRFAM: glyoxylate carboligase; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. (593 aa)
AEN13256.12-hydroxy-3-oxopropionate reductase; KEGG: sgr:SGR_1322 putative dehydrogenase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding. (297 aa)
AEN13257.1Hydroxypyruvate isomerase; KEGG: sgr:SGR_1321 putative oxidoreductase; PFAM: Xylose isomerase domain protein TIM barrel; Belongs to the hyi family. (273 aa)
AEN13258.1KEGG: sma:SAV_2022 hypothetical protein. (83 aa)
AEN13259.1KEGG: sgr:SGR_1312 hypothetical protein. (125 aa)
AEN13260.1KEGG: sgr:SGR_1311 putative OHCU decarboxylase; TIGRFAM: OHCU decarboxylase; PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. (168 aa)
AEN13261.1Hydroxyisourate hydrolase; KEGG: sgr:SGR_1310 hypothetical protein; TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (129 aa)
AEN13262.1Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. (307 aa)
AEN13263.1Xanthine permease; KEGG: sgr:SGR_1308 putative permease; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease. (466 aa)
AEN13264.1PFAM: amidohydrolase; KEGG: sgr:SGR_1307 hydroxydechloroatrazine ethylaminohydrolase. (462 aa)
AEN13282.1KEGG: sgr:SGR_1296 hypothetical protein. (193 aa)
AEN13283.1KEGG: sma:SAV_1998 hypothetical protein. (126 aa)
AEN13289.1Allantoinase; KEGG: sgr:SGR_1289 putative allantoinase; TIGRFAM: allantoinase; PFAM: amidohydrolase. (450 aa)
crcB-3Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (124 aa)
crcB-4CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (176 aa)
Your Current Organism:
Streptomyces sp. SirexAAE
NCBI taxonomy Id: 862751
Other names: S. sp. SirexAA-E, Streptomyces sp. ACTE, Streptomyces sp. SA3_actE, Streptomyces sp. SirexAA-E
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