(5 nodes) tRNA threonylcarbamoyladenosine modification, and Protein acylation network (Streptomyces sp. SirexAAE)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AEN11861.1	PFAM: protein of unknown function UPF0079; KEGG: sgr:SGR_2784 hypothetical protein. (177 aa)
	AEN11864.1	PFAM: peptidase M22 glycoprotease; KEGG: sgr:SGR_2781 hypothetical protein. (212 aa)
	AEN11865.1	KEGG: sgr:SGR_2780 putative acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase. (163 aa)
	tsaD	Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (364 aa)
	AEN11867.1	KEGG: sco:SCO4753 hypothetical protein. (89 aa)

Your Current Organism:

Streptomyces sp. SirexAAE

NCBI taxonomy Id: 862751
Other names: S. sp. SirexAA-E, Streptomyces sp. ACTE, Streptomyces sp. SA3_actE, Streptomyces sp. SirexAA-E

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEN11861.1	AEN11864.1	SACTE_4018	SACTE_4021	PFAM: protein of unknown function UPF0079; KEGG: sgr:SGR_2784 hypothetical protein.	PFAM: peptidase M22 glycoprotease; KEGG: sgr:SGR_2781 hypothetical protein.	0.985
AEN11861.1	AEN11865.1	SACTE_4018	SACTE_4022	PFAM: protein of unknown function UPF0079; KEGG: sgr:SGR_2784 hypothetical protein.	KEGG: sgr:SGR_2780 putative acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.	0.569
AEN11861.1	tsaD	SACTE_4018	SACTE_4023	PFAM: protein of unknown function UPF0079; KEGG: sgr:SGR_2784 hypothetical protein.	Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.974
AEN11864.1	AEN11861.1	SACTE_4021	SACTE_4018	PFAM: peptidase M22 glycoprotease; KEGG: sgr:SGR_2781 hypothetical protein.	PFAM: protein of unknown function UPF0079; KEGG: sgr:SGR_2784 hypothetical protein.	0.985
AEN11864.1	AEN11865.1	SACTE_4021	SACTE_4022	PFAM: peptidase M22 glycoprotease; KEGG: sgr:SGR_2781 hypothetical protein.	KEGG: sgr:SGR_2780 putative acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.	0.953
AEN11864.1	AEN11867.1	SACTE_4021	SACTE_4024	PFAM: peptidase M22 glycoprotease; KEGG: sgr:SGR_2781 hypothetical protein.	KEGG: sco:SCO4753 hypothetical protein.	0.891
AEN11864.1	tsaD	SACTE_4021	SACTE_4023	PFAM: peptidase M22 glycoprotease; KEGG: sgr:SGR_2781 hypothetical protein.	Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.997
AEN11865.1	AEN11861.1	SACTE_4022	SACTE_4018	KEGG: sgr:SGR_2780 putative acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.	PFAM: protein of unknown function UPF0079; KEGG: sgr:SGR_2784 hypothetical protein.	0.569
AEN11865.1	AEN11864.1	SACTE_4022	SACTE_4021	KEGG: sgr:SGR_2780 putative acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.	PFAM: peptidase M22 glycoprotease; KEGG: sgr:SGR_2781 hypothetical protein.	0.953
AEN11865.1	AEN11867.1	SACTE_4022	SACTE_4024	KEGG: sgr:SGR_2780 putative acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.	KEGG: sco:SCO4753 hypothetical protein.	0.891
AEN11865.1	tsaD	SACTE_4022	SACTE_4023	KEGG: sgr:SGR_2780 putative acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.	Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.992
AEN11867.1	AEN11864.1	SACTE_4024	SACTE_4021	KEGG: sco:SCO4753 hypothetical protein.	PFAM: peptidase M22 glycoprotease; KEGG: sgr:SGR_2781 hypothetical protein.	0.891
AEN11867.1	AEN11865.1	SACTE_4024	SACTE_4022	KEGG: sco:SCO4753 hypothetical protein.	KEGG: sgr:SGR_2780 putative acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.	0.891
AEN11867.1	tsaD	SACTE_4024	SACTE_4023	KEGG: sco:SCO4753 hypothetical protein.	Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.891
tsaD	AEN11861.1	SACTE_4023	SACTE_4018	Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	PFAM: protein of unknown function UPF0079; KEGG: sgr:SGR_2784 hypothetical protein.	0.974
tsaD	AEN11864.1	SACTE_4023	SACTE_4021	Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	PFAM: peptidase M22 glycoprotease; KEGG: sgr:SGR_2781 hypothetical protein.	0.997
tsaD	AEN11865.1	SACTE_4023	SACTE_4022	Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	KEGG: sgr:SGR_2780 putative acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.	0.992
tsaD	AEN11867.1	SACTE_4023	SACTE_4024	Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	KEGG: sco:SCO4753 hypothetical protein.	0.891