STRINGSTRING
AEN08207.1 AEN08207.1 AEN08209.1 AEN08209.1 AEN08795.1 AEN08795.1 AEN09296.1 AEN09296.1 AEN09300.1 AEN09300.1 AEN09301.1 AEN09301.1 AEN09302.1 AEN09302.1 psuG psuG AEN09304.1 AEN09304.1 AEN09351.1 AEN09351.1 AEN09500.1 AEN09500.1 AEN09828.1 AEN09828.1 AEN09829.1 AEN09829.1 AEN09866.1 AEN09866.1 AEN10834.1 AEN10834.1 AEN10969.1 AEN10969.1 AEN10971.1 AEN10971.1 upp upp AEN11420.1 AEN11420.1 AEN11441.1 AEN11441.1 AEN11782.1 AEN11782.1 AEN11783.1 AEN11783.1 AEN11790.1 AEN11790.1 AEN11984.1 AEN11984.1 AEN11985.1 AEN11985.1 AEN11986.1 AEN11986.1 AEN11987.1 AEN11987.1 AEN11988.1 AEN11988.1 AEN11989.1 AEN11989.1 AEN11990.1 AEN11990.1 AEN11991.1 AEN11991.1 AEN11992.1 AEN11992.1 add add AEN12009.1 AEN12009.1 AEN12016.1 AEN12016.1 AEN12626.1 AEN12626.1 AEN14097.1 AEN14097.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEN08207.1PFAM: sodium/calcium exchanger membrane region; KEGG: sma:SAV_6277 ionic transporter integral membrane protein. (407 aa)
AEN08209.1PFAM: protein of unknown function DUF541; KEGG: sgr:SGR_1454 hypothetical protein. (213 aa)
AEN08795.1KEGG: sco:SCO6439 DNA-binding protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. (143 aa)
AEN09296.1PFAM: Integral membrane protein TerC; KEGG: sgr:SGR_5561 putative integral membrane export protein. (333 aa)
AEN09300.1PFAM: MHYT domain protein; KEGG: sgr:SGR_5557 putative integral membrane protein. (290 aa)
AEN09301.1PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: sgr:SGR_5556 putative secreted hydrolase. (293 aa)
AEN09302.1methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (181 aa)
psuGIndigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (319 aa)
AEN09304.1PFAM: PfkB domain protein; KEGG: sgr:SGR_5551 putative sugar kinase; Belongs to the carbohydrate kinase PfkB family. (300 aa)
AEN09351.12',3'-cyclic-nucleotide 2'-phosphodiesterase; KEGG: sgr:SGR_5514 putative 5'-nucleotidase; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Twin-arginine translocation pathway, signal sequence, subgroup; Belongs to the 5'-nucleotidase family. (603 aa)
AEN09500.1Adenosine kinase; KEGG: sgr:SGR_5350 putative carbohydrate kinase; PFAM: PfkB domain protein. (324 aa)
AEN09828.1TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: sma:SAV_5674 deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily. (447 aa)
AEN09829.1PFAM: protein of unknown function DUF218; KEGG: sma:SAV_5672 integral membrane protein. (245 aa)
AEN09866.1Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (330 aa)
AEN10834.1PFAM: purine or other phosphorylase family 1; KEGG: emi:Emin_0020 purine phosphorylase family 1. (268 aa)
AEN10969.1PFAM: phosphoribosyltransferase; KEGG: sgr:SGR_3439 putative purine phosphoribosyltransferase. (166 aa)
AEN10971.1Manually curated; KEGG: sgr:SGR_3441 hypothetical protein. (57 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)
AEN11420.1PFAM: adenosine/AMP deaminase; KEGG: sgr:SGR_682 putative adenosine deaminase. (529 aa)
AEN11441.1PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: sgr:SGR_3941 putative 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (605 aa)
AEN11782.1PFAM: NAD-dependent epimerase/dehydratase; KEGG: sgr:SGR_2886 hypothetical protein. (218 aa)
AEN11783.1PFAM: Amidohydrolase 3; KEGG: sgr:SGR_2885 hypothetical protein. (415 aa)
AEN11790.1TIGRFAM: adenosine deaminase; KEGG: sgr:SGR_2878 adenosine deaminase; PFAM: adenosine/AMP deaminase. (342 aa)
AEN11984.1Amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; manually curated; KEGG: sgr:SGR_2655 M20/M25/M40 family peptidase; TIGRFAM: amidohydrolase. (406 aa)
AEN11985.1PFAM: basic membrane lipoprotein; KEGG: sgr:SGR_2654 putative lipoprotein. (352 aa)
AEN11986.1KEGG: sgr:SGR_2653 putative sugar ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (560 aa)
AEN11987.1PFAM: inner-membrane translocator; KEGG: sgr:SGR_2652 putative sugar ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (372 aa)
AEN11988.1PFAM: inner-membrane translocator; KEGG: sgr:SGR_2651 putative sugar ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (421 aa)
AEN11989.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (133 aa)
AEN11990.1TIGRFAM: pyrimidine-nucleoside phosphorylase; KEGG: sgr:SGR_2649 thymidine phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like. (425 aa)
AEN11991.1KEGG: sgr:SGR_3203 hypothetical protein. (45 aa)
AEN11992.1KEGG: sgr:SGR_2647 hypothetical protein. (114 aa)
addTIGRFAM: adenosine deaminase; KEGG: sgr:SGR_2641 adenosine deaminase; PFAM: adenosine/AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (410 aa)
AEN12009.1Putative ATP-binding protein; Manually curated; KEGG: sgr:SGR_2633 putative ATP-binding protein. (246 aa)
AEN12016.1Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (274 aa)
AEN12626.1PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sco:SCO5579 transmembrane protein; Belongs to the purine-cytosine permease (2.A.39) family. (476 aa)
AEN14097.1Adenosine kinase; KEGG: sma:SAV_6045 carbohydrate kinase; PFAM: PfkB domain protein. (324 aa)
Your Current Organism:
Streptomyces sp. SirexAAE
NCBI taxonomy Id: 862751
Other names: S. sp. SirexAA-E, Streptomyces sp. ACTE, Streptomyces sp. SA3_actE, Streptomyces sp. SirexAA-E
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.