STRINGSTRING
hemH hemH AEN08203.1 AEN08203.1 AEN08888.1 AEN08888.1 AEN09270.1 AEN09270.1 ctaB ctaB AEN09610.1 AEN09610.1 hemL hemL AEN10658.1 AEN10658.1 hemC hemC hemA hemA AEN12573.1 AEN12573.1 hemC-2 hemC-2 AEN13226.1 AEN13226.1 AEN13145.1 AEN13145.1 AEN13079.1 AEN13079.1 AEN13078.1 AEN13078.1 hemE hemE AEN12795.1 AEN12795.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (375 aa)
AEN08203.1PFAM: SchA/CurD domain protein; Antibiotic biosynthesis monooxygenase; KEGG: sma:SAV_2836 WhiE I-like protein. (372 aa)
AEN08888.1KEGG: sgr:SGR_5984 putative uroporphyrin-III methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. (413 aa)
AEN09270.1PFAM: cytochrome oxidase assembly; KEGG: sgr:SGR_5591 putative cytochrome c oxidase subunit XV assembly protein. (336 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (317 aa)
AEN09610.1Heme oxygenase; KEGG: sgr:SGR_5243 putative heme oxygenase; PFAM: Haem oxygenase-like. (226 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; KEGG: sgr:SGR_4192 glutamate-1-semialdehyde aminotransferase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. (435 aa)
AEN10658.1Porphobilinogen synthase; KEGG: sgr:SGR_4158 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (331 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (328 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (499 aa)
AEN12573.1KEGG: sro:Sros_5022 hypothetical protein. (204 aa)
hemC-2Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa)
AEN13226.1KEGG: sma:SAV_7325 hypothetical protein. (141 aa)
AEN13145.1PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: sgr:SGR_1400 hypothetical protein. (250 aa)
AEN13079.1PFAM: Chlorite dismutase; KEGG: sgr:SGR_1469 hypothetical protein. (237 aa)
AEN13078.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (487 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (356 aa)
AEN12795.1KEGG: sgr:SGR_1713 hypothetical protein. (196 aa)
Your Current Organism:
Streptomyces sp. SirexAAE
NCBI taxonomy Id: 862751
Other names: S. sp. SirexAA-E, Streptomyces sp. ACTE, Streptomyces sp. SA3_actE, Streptomyces sp. SirexAA-E
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