STRINGSTRING
frlR frlR SCI_0070 SCI_0070 SCI_0071 SCI_0071 SCI_0072 SCI_0072 SCI_0073 SCI_0073 SCI_0074 SCI_0074 agaS agaS galM galM SCI_0110 SCI_0110 nanE nanE SCI_0112 SCI_0112 SCI_0113 SCI_0113 SCI_0114 SCI_0114 SCI_0115 SCI_0115 SCI_0116 SCI_0116 SCI_0117 SCI_0117 bglK bglK SCI_0266 SCI_0266 gmuC_1 gmuC_1 SCI_0269 SCI_0269 SCI_0270 SCI_0270 SCI_0275 SCI_0275 manO manO manN manN manM manM manL manL nagA nagA treR treR nagB nagB celA celA celR celR celC1 celC1 SCI_0610 SCI_0610 celD celD glgB glgB glgC glgC glgD glgD glgA glgA glgP glgP fruR fruR fruB fruB fruA fruA SCI_0697 SCI_0697 pgm pgm birA birA galR galR galK galK galT galT SCI_0769 SCI_0769 obgE obgE SCI_0771 SCI_0771 SCI_0838 SCI_0838 pulA pulA yvoA_2 yvoA_2 amy amy glcK glcK galE galE SCI_1362 SCI_1362 gmuB gmuB chbA chbA ptsI ptsI ptsH ptsH SCI_1404 SCI_1404 lacG lacG lacE lacE lacF lacF lacT lacT lacZ lacZ lacC lacC SCI_1411 SCI_1411 SCI_1412 SCI_1412 SCI_1413 SCI_1413 lacA lacA lacB lacB SCI_1416 SCI_1416 SCI_1514 SCI_1514 SCI_1515 SCI_1515 manA manA SCI_1587 SCI_1587 SCI_1588 SCI_1588 SCI_1589 SCI_1589 celC celC celB celB scrK scrK scrA scrA scrB scrB scrR scrR regR regR SCI_1630 SCI_1630 manZ_2 manZ_2 SCI_1633 SCI_1633 sorB sorB SCI_1635 SCI_1635 SCI_1636 SCI_1636 gno gno SCI_1638 SCI_1638 SCI_1639 SCI_1639 SCI_1640 SCI_1640 SCI_1642 SCI_1642 SCI_1652 SCI_1652 lrp lrp pulA2 pulA2 SCI_1691 SCI_1691 manZ_3 manZ_3 manY manY levE_2 levE_2 SCI_1695 SCI_1695 SCI_1696 SCI_1696 nreC nreC desK_2 desK_2 SCI_1699 SCI_1699 pheT_2 pheT_2 SCI_1703 SCI_1703 pepA pepA glmS glmS glnA glnA galU galU SCI_1815 SCI_1815 SCI_1857 SCI_1857 malQ malQ malX malX malC malC malD malD malA malA malR malR pulA1 pulA1 galE1 galE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
frlRPutative GntR family transcriptional regulator. (238 aa)
SCI_0070Putative beta-galactosidase; Belongs to the glycosyl hydrolase 35 family. (595 aa)
SCI_0071Putative phosphotransferase system sugar-specific EIIB component. (158 aa)
SCI_0072Putative PTS phosphotransferase system sugar-specific EIIC component. (297 aa)
SCI_0073Putative mannose permease IID component. (275 aa)
SCI_0074Putative PTS system, mannose-specific IIA component. (134 aa)
agaSPutative sugar isomerase domain protein. (417 aa)
galMPutative aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (345 aa)
SCI_0110Phosphatase. (182 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (234 aa)
SCI_0112Sugar ABC transporter, sugar-binding protein. (441 aa)
SCI_0113Putative ABC transporter permease protein yurN. (295 aa)
SCI_0114Sugar ABC transporter, sugar-binding protein. (276 aa)
SCI_0115Hypothetical protein. (150 aa)
SCI_0116Hypothetical protein. (215 aa)
SCI_0117Putative N-acetylneuraminate lyase. (305 aa)
bglKPutative glucokinase/N-acylmannosamine kinase. (294 aa)
SCI_0266Putative ROK family protein. (392 aa)
gmuC_1PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (421 aa)
SCI_0269PTS system, lactose/cellobiose-specific IIB component. (106 aa)
SCI_0270PTS system, IIA subunit. (107 aa)
SCI_02756-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. (479 aa)
manOHypothetical protein. (123 aa)
manNPTS system, mannose-specific IID component. (303 aa)
manMPTS system, mannose-specific IIC component. (268 aa)
manLPutative phosphotransferase system, mannose-specific EIIAB. (329 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase. (384 aa)
treRTrehalose operon repressor. (237 aa)
nagBPutative glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (235 aa)
celA6-phospho-beta-glucosidase. (478 aa)
celRPutative transcriptional regulator. (663 aa)
celC1Putative PTS system, cellobiose-specific IIA component. (105 aa)
SCI_0610Hypothetical protein. (168 aa)
celDPutative phosphotransferase (PTS) system. (447 aa)
glgBGlycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (636 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (380 aa)
glgDGlucose-1-phosphate adenylyltransferase, GlgD subunit. (379 aa)
glgAGlycogen synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (476 aa)
glgPPutative glycogen/starch phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (799 aa)
fruRPhosphotransferase system repressor. (205 aa)
fruB1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (303 aa)
fruAPutative PTS system, fructose-specific enzyme IIABC component. (649 aa)
SCI_0697GNAT family acetyltransferase. (157 aa)
pgmPutative phosphoglucomutase/phosphomannomutase. (572 aa)
birABiotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (311 aa)
galRGalactose operon transcriptional regulator GalR. (333 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (392 aa)
galTGalactose-1-phosphate uridylyltransferase. (493 aa)
SCI_0769Hypothetical protein. (44 aa)
obgEGTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (437 aa)
SCI_0771Hypothetical protein. (53 aa)
SCI_0838Nucleotide sugar dehydrogenase. (398 aa)
pulAPullulanase, type I; Belongs to the glycosyl hydrolase 13 family. (766 aa)
yvoA_2Hypothetical protein. (232 aa)
amyCytoplasmic alpha-amylase. (482 aa)
glcKGlucokinase putative. (319 aa)
galEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (339 aa)
SCI_1362PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (433 aa)
gmuBPTS system, cellobiose-specific IIB component. (106 aa)
chbAPTS system, IIA component. (107 aa)
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)
ptsHPhosphocarrier protein HPr. (87 aa)
SCI_1404Hypothetical protein. (177 aa)
lacG6-phospho-beta-galactosidase; Belongs to the glycosyl hydrolase 1 family. (468 aa)
lacEPTS system, lactose-specific IIBC component. (567 aa)
lacFPTS system, lactose-specific IIA component. (106 aa)
lacTTranscription antiterminator. (277 aa)
lacZBeta-galactosidase. (2222 aa)
lacCFructose-1-phosphate/tagatose-6-phosphate kinase-like protein; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (321 aa)
SCI_1411Putative PTS system IIC component. (491 aa)
SCI_1412Putative PTS system, IIB component. (101 aa)
SCI_1413PTS system enzyme IIBC component. (160 aa)
lacAPutative galactose-6-phosphate isomerase subunit LacA. (174 aa)
lacBPutative galactose-6-phosphate isomerase subunit LacB. (172 aa)
SCI_1416Putative lactose phosphotransferase system transcriptional repressor. (248 aa)
SCI_1514Hypothetical protein. (271 aa)
SCI_1515PTS system glucose-specific EIICBA component. (729 aa)
manAMannose-6-phosphate isomerase, class I; Belongs to the mannose-6-phosphate isomerase type 1 family. (314 aa)
SCI_1587GentR family transcriptional regulator. (241 aa)
SCI_1588PTS system, lactose/cellobiose family IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (422 aa)
SCI_1589Beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. (465 aa)
celCCellobiose phosphotransferase system IIA component. (106 aa)
celBPTS system, IIB component. (104 aa)
scrKPutative fructokinase. (299 aa)
scrAPTS system, sucrose-specific IIABC component. (632 aa)
scrBSucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (484 aa)
scrRSucrose regulon regulatory protein. (321 aa)
regRPutative sugar binding transcriptional regulator. (334 aa)
SCI_1630Hypothetical protein. (632 aa)
manZ_2PTS system, N-acetylgalactosamine-specific IID component. (271 aa)
SCI_1633PTS system, N-acetylgalactosamine-specific IIC component. (260 aa)
sorBPTS system, N-acetylgalactosamine-specific IIB component. (163 aa)
SCI_1635Glucuronyl hydrolase. (396 aa)
SCI_1636PTS system, N-acetylgalactosamine-specific IIA component. (144 aa)
gnoGluconate 5-dehydrogenase. (271 aa)
SCI_1638Putative ribose/galactose isomerase. (213 aa)
SCI_1639Carbohydrate kinase. (333 aa)
SCI_1640Putative 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase. (209 aa)
SCI_1642Hyaluronate lyase precursor. (1063 aa)
SCI_1652ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily. (376 aa)
lrpHypothetical protein. (290 aa)
pulA2Putative alkaline amylopullulanase. (1235 aa)
SCI_1691Hypothetical protein. (95 aa)
manZ_3Phosphotransferase system, sugar-specific component IID. (276 aa)
manYPhosphotransferase system, IIC component. (282 aa)
levE_2PTS system, sugar-specific IIB component. (164 aa)
SCI_1695PTS system, sugar-specific IIA component. (144 aa)
SCI_1696Putative sugar-binding periplasmic protein. (419 aa)
nreCPutative two-component response transcriptional regulator. (227 aa)
desK_2Putative two-component sensor histidine kinase. (437 aa)
SCI_1699Putative periplasmic sugar-binding protein. (328 aa)
pheT_2tRNA-binding domain-containing protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (208 aa)
SCI_1703Hypothetical protein. (95 aa)
pepAGlutamyl aminopeptidase. (354 aa)
glmSD-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (604 aa)
glnAGlutamine synthetase. (448 aa)
galUUTP-glucose-1-phosphate uridylyltransferase. (299 aa)
SCI_1815Putative PTS enzyme. (564 aa)
SCI_1857Putative glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (753 aa)
malQ4-alpha-glucanotransferase. (507 aa)
malXMaltose/maltodextrin-binding protein. (420 aa)
malCMaltose/maltodextrin transport system permease protein. (431 aa)
malDMaltose/maltodextrin transport system permease protein. (280 aa)
malAMaltodextrose utilization protein. (270 aa)
malRMaltose operon transcriptional repressor. (328 aa)
pulA1Type I pullulanase; Belongs to the glycosyl hydrolase 13 family. (691 aa)
galE1UDP-glucose 4-epimerase. (331 aa)
Your Current Organism:
Streptococcus constellatus
NCBI taxonomy Id: 862969
Other names: S. constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis str. C1050, Streptococcus constellatus subsp. pharyngis strain C1050
Server load: low (36%) [HD]