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| | SCI_0244 | Phosphomevalonate kinase. (332 aa) |
| | mvaD | Diphosphomevalonate decarboxylase. (314 aa) |
| | mvk | Mevalonate kinase. (292 aa) |
| | SCI_0221 | Hypothetical protein; Belongs to the UPF0356 family. (76 aa) |
| | thiN | Thiamine pyrophosphokinase. (210 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (503 aa) |
| | SCI_0133 | Hypothetical protein. (525 aa) |
| | bglK | Putative glucokinase/N-acylmannosamine kinase. (294 aa) |
| | comD | Histidine kinase. (437 aa) |
| | pgsA | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (179 aa) |
| | SCI_1917 | Putative phosphoglycolate phosphatase. (218 aa) |
| | SCI_1911 | Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. (658 aa) |
| | cls | Putative cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (510 aa) |
| | saeS | Histidine kinase. (343 aa) |
| | SCI_1815 | Putative PTS enzyme. (564 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (881 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (312 aa) |
| | SCI_1758 | Hypothetical protein. (129 aa) |
| | galU | UTP-glucose-1-phosphate uridylyltransferase. (299 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1188 aa) |
| | rpoC | DNA-directed RNA polymerase, subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1212 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa) |
| | ulaB_2 | Putative phosphotransferase system sugar-specific EII component. (98 aa) |
| | SCI_1716 | Phosphotransferase. (556 aa) |
| | cdsA | Putative phosphatidate cytidylyltransferase; Belongs to the CDS family. (267 aa) |
| | desK_2 | Putative two-component sensor histidine kinase. (437 aa) |
| | levE_2 | PTS system, sugar-specific IIB component. (164 aa) |
| | manY | Phosphotransferase system, IIC component. (282 aa) |
| | manZ_3 | Phosphotransferase system, sugar-specific component IID. (276 aa) |
| | SCI_1687 | Deoxynucleoside kinase. (212 aa) |
| | relA | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (738 aa) |
| | polC | DNA polymerase III subunit alpha, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1464 aa) |
| | lacD | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (333 aa) |
| | SCI_0074 | Putative PTS system, mannose-specific IIA component. (134 aa) |
| | SCI_0071 | Putative phosphotransferase system sugar-specific EIIB component. (158 aa) |
| | dhaM | PTS IIA component superfamily protein. (124 aa) |
| | SCI_0066 | Putative dihydroxyacetone kinase. (184 aa) |
| | SCI_0065 | Putative dihydroxyacetone kinase, DAK1 domain-containing protein. (329 aa) |
| | SCI_0063 | Putative dihydroxyacetone kinase. (328 aa) |
| | prs1 | Putative ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa) |
| | dnaN | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (378 aa) |
| | pnpA | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (726 aa) |
| | SCI_1639 | Carbohydrate kinase. (333 aa) |
| | SCI_1636 | PTS system, N-acetylgalactosamine-specific IIA component. (144 aa) |
| | sorB | PTS system, N-acetylgalactosamine-specific IIB component. (163 aa) |
| | SCI_1624 | Putative PTS system, IIA component. (685 aa) |
| | ulaB_1 | Putative PTS system IIB component. (108 aa) |
| | thiD | Phosphomethylpyrimidine kinase. (257 aa) |
| | rpoE | DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (195 aa) |
| | scrA | PTS system, sucrose-specific IIABC component. (632 aa) |
| | scrK | Putative fructokinase. (299 aa) |
| | celB | PTS system, IIB component. (104 aa) |
| | SCI_1588 | PTS system, lactose/cellobiose family IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (422 aa) |
| | acpS | Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (133 aa) |
| | nadD | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (213 aa) |
| | SCI_1515 | PTS system glucose-specific EIICBA component. (729 aa) |
| | lacD1 | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (316 aa) |
| | SCI_1412 | Putative PTS system, IIB component. (101 aa) |
| | lacC | Fructose-1-phosphate/tagatose-6-phosphate kinase-like protein; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (321 aa) |
| | lacE | PTS system, lactose-specific IIBC component. (567 aa) |
| | ptsI | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa) |
| | SCI_1374 | Hypothetical protein. (214 aa) |
| | gmuB | PTS system, cellobiose-specific IIB component. (106 aa) |
| | SCI_1362 | PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (433 aa) |
| | SCI_1358 | Hypothetical protein. (210 aa) |
| | SCI_1353 | Hypothetical protein. (280 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (158 aa) |
| | SCI_1323 | Putative transcriptional regulator. (444 aa) |
| | SCI_1288 | Hypothetical protein. (624 aa) |
| | rmlA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | vicK | Putative histidine sensory kinase. (450 aa) |
| | SCI_1163 | Putative phage-related DNA polymerase. (960 aa) |
| | SCI_1116 | Hypothetical protein. (92 aa) |
| | hprK | HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (310 aa) |
| | dacA-2 | Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (285 aa) |
| | SCI_1095 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. (370 aa) |
| | cmk | Cytidylate kinase. (225 aa) |
| | udk | Uridine kinase. (211 aa) |
| | ppdK | Pyruvate phosphate, orthophosphate dikinase. (869 aa) |
| | yqfL | Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (274 aa) |
| | thiI | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (404 aa) |
| | ndk | Nucleoside diphosphate kinase. (139 aa) |
| | SCI_1025 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (326 aa) |
| | glcK | Glucokinase putative. (319 aa) |
| | ciaH | Putative sensor histidine kinase. (448 aa) |
| | flaR | Topology modulation protein. (169 aa) |
| | coaA | Pantothenate kinase. (306 aa) |
| | SCI_0977 | Hypothetical protein. (205 aa) |
| | fic | Putative fic family protein. (201 aa) |
| | SCI_0971 | Putative aminoglycoside adenylyltransferase. (269 aa) |
| | lplA | Lipoyltransferase and lipoate-protein ligase. (329 aa) |
| | tdk | Thymidine kinase. (201 aa) |
| | SCI_0904 | Putative histidine kinase. (569 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (599 aa) |
| | dagK | Putative lipid kinase. (323 aa) |
| | SCI_0877 | Putative membrane protein, putative toxin regulator. (349 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
| | SCI_0804 | Hypothetical protein. (203 aa) |
| | dgkA | Diacylglycerol kinase. (134 aa) |
| | SCI_0776 | Component of a phospotransferase system. (461 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (288 aa) |
| | galT | Galactose-1-phosphate uridylyltransferase. (493 aa) |
| | galK | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (392 aa) |
| | dnaX | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (554 aa) |
| | ppnK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (272 aa) |
| | SCI_0740 | GTP pyrophosphokinase. (223 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa) |
| | ribF | Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (310 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (500 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (336 aa) |
| | dnaE | DNA polymerase III, alpha subunit. (1033 aa) |
| | SCI_0704 | Hypothetical protein. (203 aa) |
| | SCI_0696 | Hypothetical protein. (260 aa) |
| | papS | tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (406 aa) |
| | fruA | Putative PTS system, fructose-specific enzyme IIABC component. (649 aa) |
| | fruB | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (303 aa) |
| | glgD | Glucose-1-phosphate adenylyltransferase, GlgD subunit. (379 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (380 aa) |
| | SCI_0642 | Putative two component system histidine kinase. (458 aa) |
| | dinG | Putative DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. (819 aa) |
| | celD | Putative phosphotransferase (PTS) system. (447 aa) |
| | celR | Putative transcriptional regulator. (663 aa) |
| | arcC | Carbamate kinase; Belongs to the carbamate kinase family. (315 aa) |
| | SCI_0582 | Putative histidine kinase. (435 aa) |
| | holA | DNA polymerase III subunit delta. (345 aa) |
| | pyrH | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) |
| | glmU | Putative glucosamine-1-phosphate acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa) |
| | graS | Putative signal transduction histidine kinase. (326 aa) |
| | holB | DNA polymerase III subunit delta'. (297 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa) |
| | SCI_0444 | Putative aminoglycoside 3'-phosphotransferase; Belongs to the aminoglycoside phosphotransferase family. (258 aa) |
| | SCI_0437 | Putative histidine kinase. (331 aa) |
| | pkn | Putative serine/threonine protein kinase. (627 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (104 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (208 aa) |
| | rgpG | Putative glycosyl transferase N-acetylglucosaminyltransferase. (386 aa) |
| | SCI_0380 | Putative kinase. (555 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (327 aa) |
| | SCI_0344 | Hypothetical protein. (265 aa) |
| | SCI_0339 | Putative transcriptional regulator LytR. (368 aa) |
| | manL | Putative phosphotransferase system, mannose-specific EIIAB. (329 aa) |
| | manM | PTS system, mannose-specific IIC component. (268 aa) |
| | manN | PTS system, mannose-specific IID component. (303 aa) |
| | lysC | Aspartate kinase; Belongs to the aspartokinase family. (452 aa) |
| | SCI_0269 | PTS system, lactose/cellobiose-specific IIB component. (106 aa) |
| | gmuC_1 | PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (421 aa) |
| | dinP | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (355 aa) |
