(65 nodes) RHOD GTPase cycle, and RAC1 GTPase cycle network (Rhizopus azygosporus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CU097_000313	Uncharacterized protein. (129 aa)
	RAC1_1	Rho GTPase protein rac1. (79 aa)
	STE20_1	Signal transducing kinase of the PAK. (250 aa)
	RHO1_2	GTP-binding protein Rho1. (95 aa)
	CU097_000286	Rho-GAP domain-containing protein. (392 aa)
	CU097_004064	Rho-GAP domain-containing protein. (239 aa)
	CU097_003972	Uncharacterized protein. (195 aa)
	CU097_001481	F-BAR domain-containing protein. (427 aa)
	RHO3_2	Rho GTPase. (197 aa)
	CU097_003274	Uncharacterized protein. (501 aa)
	RAC1_2	Rho GTPase protein rac1. (191 aa)
	CU097_001462	Uncharacterized protein. (889 aa)
	CU097_004603	Uncharacterized protein. (253 aa)
	GAP1_2	Glyceraldehyde-3-phosphate dehydrogenase 1. (806 aa)
	CLA4_1	Non-specific serine/threonine protein kinase. (619 aa)
	CU097_000741	Ras-GAP domain-containing protein. (1077 aa)
	CDC42_2	Rho GTPase. (191 aa)
	PAK1_2	Non-specific serine/threonine protein kinase. (514 aa)
	CU097_000477	Uncharacterized protein. (301 aa)
	CU097_007139	Uncharacterized protein. (550 aa)
	BEM1_1	Bud emergence protein 1. (429 aa)
	CU097_007767	Rho-GAP domain-containing protein. (469 aa)
	RHO1_3	GTP-binding protein Rho1. (193 aa)
	CDC42_1	Rho GTPase. (191 aa)
	CU097_009262	Uncharacterized protein. (644 aa)
	CU097_009818	Uncharacterized protein. (412 aa)
	CU097_010069	Uncharacterized protein. (438 aa)
	CU097_005571	Uncharacterized protein. (1021 aa)
	CU097_008521	Uncharacterized protein. (1021 aa)
	CU097_004588	Rho-GAP domain-containing protein. (427 aa)
	STE20_8	Signal transducing kinase of the PAK; Belongs to the protein kinase superfamily. (292 aa)
	CU097_009523	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
	CU097_009199	Uncharacterized protein. (123 aa)
	RAC1_4	Rho GTPase protein rac1. (96 aa)
	CU097_003975	Uncharacterized protein. (524 aa)
	CU097_010499	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (123 aa)
	CU097_003051	Uncharacterized protein. (1304 aa)
	CU097_002048	Uncharacterized protein. (407 aa)
	RHO4	Rho GTPase. (196 aa)
	CU097_010846	Uncharacterized protein. (207 aa)
	CU097_003942	Rho-GAP domain-containing protein. (761 aa)
	CU097_006815	Uncharacterized protein. (827 aa)
	CU097_011266	Uncharacterized protein. (784 aa)
	CU097_011715	Uncharacterized protein. (868 aa)
	CU097_009881	Myb-like domain-containing protein. (300 aa)
	CU097_007777	Uncharacterized protein. (837 aa)
	CU097_002999	Uncharacterized protein. (2045 aa)
	CU097_003676	Uncharacterized protein. (187 aa)
	CU097_013696	Uncharacterized protein. (524 aa)
	BEM1_3	Bud emergence protein 1. (485 aa)
	CU097_009323	Uncharacterized protein. (195 aa)
	STE20_10	Non-specific serine/threonine protein kinase. (636 aa)
	CU097_015161	Uncharacterized protein. (402 aa)
	MPK1_5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (715 aa)
	CU097_013710	Uncharacterized protein. (986 aa)
	CU097_009494	Uncharacterized protein. (195 aa)
	CU097_012177	Uncharacterized protein. (813 aa)
	CU097_013960	Rho-GAP domain-containing protein. (466 aa)
	CLA4_3	Non-specific serine/threonine protein kinase. (611 aa)
	RHO1_1	GTP-binding protein Rho1. (344 aa)
	RHO1_5	GTP-binding protein Rho1. (198 aa)
	CU097_011362	Uncharacterized protein. (977 aa)
	BEM2	Rho GTPase-activating protein. (1592 aa)
	CU097_010759	Uncharacterized protein. (1005 aa)
	CU097_013118	Uncharacterized protein. (464 aa)

Your Current Organism:

Rhizopus azygosporus

NCBI taxonomy Id: 86630
Other names: ATCC 48108, CBS 357.93, R. azygosporus, Rhizopus microsporus var. azygosporus

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BEM1_1	BEM2	A0A367J357	A0A367KF90	Bud emergence protein 1.	Rho GTPase-activating protein.	0.458
BEM1_1	CDC42_1	A0A367J357	A0A367J949	Bud emergence protein 1.	Rho GTPase.	0.949
BEM1_1	CDC42_2	A0A367J357	A0A367J1A9	Bud emergence protein 1.	Rho GTPase.	0.949
BEM1_1	CLA4_1	A0A367J357	A0A367J000	Bud emergence protein 1.	Non-specific serine/threonine protein kinase.	0.822
BEM1_1	CLA4_3	A0A367J357	A0A367KCH7	Bud emergence protein 1.	Non-specific serine/threonine protein kinase.	0.822
BEM1_1	CU097_003274	A0A367J357	A0A367ITM5	Bud emergence protein 1.	Uncharacterized protein.	0.402
BEM1_1	CU097_003676	A0A367J357	A0A367K0L4	Bud emergence protein 1.	Uncharacterized protein.	0.611
BEM1_1	CU097_003972	A0A367J357	A0A367IRS5	Bud emergence protein 1.	Uncharacterized protein.	0.611
BEM1_1	CU097_004603	A0A367J357	A0A367IXM2	Bud emergence protein 1.	Uncharacterized protein.	0.602
BEM1_1	CU097_005571	A0A367J357	A0A367JBC8	Bud emergence protein 1.	Uncharacterized protein.	0.402
BEM1_1	CU097_006815	A0A367J357	A0A367JU78	Bud emergence protein 1.	Uncharacterized protein.	0.697
BEM1_1	CU097_007139	A0A367J357	A0A367J2P4	Bud emergence protein 1.	Uncharacterized protein.	0.402
BEM1_1	CU097_007777	A0A367J357	A0A367JYU6	Bud emergence protein 1.	Uncharacterized protein.	0.697
BEM1_1	CU097_008521	A0A367J357	A0A367JCS6	Bud emergence protein 1.	Uncharacterized protein.	0.402
BEM1_1	CU097_009262	A0A367J357	A0A367JAF8	Bud emergence protein 1.	Uncharacterized protein.	0.697
BEM1_1	CU097_009523	A0A367J357	A0A367JGK7	Bud emergence protein 1.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.822
BEM1_1	CU097_009881	A0A367J357	A0A367JYR0	Bud emergence protein 1.	Myb-like domain-containing protein.	0.611
BEM1_1	CU097_010846	A0A367J357	A0A367JM87	Bud emergence protein 1.	Uncharacterized protein.	0.402
BEM1_1	CU097_011266	A0A367J357	A0A367JUS3	Bud emergence protein 1.	Uncharacterized protein.	0.897
BEM1_1	CU097_011715	A0A367J357	A0A367JX33	Bud emergence protein 1.	Uncharacterized protein.	0.697