(5 nodes) Double-strand break repair via nonhomologous end joining network (Rhizopus azygosporus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	XRCC6_2	X-ray repair cross-complementing protein 6. (102 aa)
	KU80_1	ATP-dependent DNA helicase II subunit 2. (734 aa)
	LIG4_2	DNA ligase (ATP); Belongs to the ATP-dependent DNA ligase family. (838 aa)
	CU097_002815	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2148 aa)
	CU097_011667	Uncharacterized protein. (1292 aa)

Your Current Organism:

Rhizopus azygosporus

NCBI taxonomy Id: 86630
Other names: ATCC 48108, CBS 357.93, R. azygosporus, Rhizopus microsporus var. azygosporus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CU097_002815	CU097_011667	A0A367JR09	A0A367JRR6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.947
CU097_002815	KU80_1	A0A367JR09	A0A367J1T8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	ATP-dependent DNA helicase II subunit 2.	0.946
CU097_002815	LIG4_2	A0A367JR09	A0A367J4B7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	DNA ligase (ATP); Belongs to the ATP-dependent DNA ligase family.	0.915
CU097_002815	XRCC6_2	A0A367JR09	A0A367IXZ3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	X-ray repair cross-complementing protein 6.	0.943
CU097_011667	CU097_002815	A0A367JRR6	A0A367JR09	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.947
CU097_011667	KU80_1	A0A367JRR6	A0A367J1T8	Uncharacterized protein.	ATP-dependent DNA helicase II subunit 2.	0.946
CU097_011667	LIG4_2	A0A367JRR6	A0A367J4B7	Uncharacterized protein.	DNA ligase (ATP); Belongs to the ATP-dependent DNA ligase family.	0.915
CU097_011667	XRCC6_2	A0A367JRR6	A0A367IXZ3	Uncharacterized protein.	X-ray repair cross-complementing protein 6.	0.943
KU80_1	CU097_002815	A0A367J1T8	A0A367JR09	ATP-dependent DNA helicase II subunit 2.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.946
KU80_1	CU097_011667	A0A367J1T8	A0A367JRR6	ATP-dependent DNA helicase II subunit 2.	Uncharacterized protein.	0.946
KU80_1	LIG4_2	A0A367J1T8	A0A367J4B7	ATP-dependent DNA helicase II subunit 2.	DNA ligase (ATP); Belongs to the ATP-dependent DNA ligase family.	0.980
KU80_1	XRCC6_2	A0A367J1T8	A0A367IXZ3	ATP-dependent DNA helicase II subunit 2.	X-ray repair cross-complementing protein 6.	0.989
LIG4_2	CU097_002815	A0A367J4B7	A0A367JR09	DNA ligase (ATP); Belongs to the ATP-dependent DNA ligase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.915
LIG4_2	CU097_011667	A0A367J4B7	A0A367JRR6	DNA ligase (ATP); Belongs to the ATP-dependent DNA ligase family.	Uncharacterized protein.	0.915
LIG4_2	KU80_1	A0A367J4B7	A0A367J1T8	DNA ligase (ATP); Belongs to the ATP-dependent DNA ligase family.	ATP-dependent DNA helicase II subunit 2.	0.980
LIG4_2	XRCC6_2	A0A367J4B7	A0A367IXZ3	DNA ligase (ATP); Belongs to the ATP-dependent DNA ligase family.	X-ray repair cross-complementing protein 6.	0.979
XRCC6_2	CU097_002815	A0A367IXZ3	A0A367JR09	X-ray repair cross-complementing protein 6.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.943
XRCC6_2	CU097_011667	A0A367IXZ3	A0A367JRR6	X-ray repair cross-complementing protein 6.	Uncharacterized protein.	0.943
XRCC6_2	KU80_1	A0A367IXZ3	A0A367J1T8	X-ray repair cross-complementing protein 6.	ATP-dependent DNA helicase II subunit 2.	0.989
XRCC6_2	LIG4_2	A0A367IXZ3	A0A367J4B7	X-ray repair cross-complementing protein 6.	DNA ligase (ATP); Belongs to the ATP-dependent DNA ligase family.	0.979