5 items (Methanothermobacter sp. CaT2) - STRING interaction network

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Your Input:
	cimA	2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. (496 aa)
	ilvC	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (328 aa)
	MTCT_1311	Acetolactate synthase regulatory subunit. (165 aa)
	MTCT_1312	Acetolactate synthase catalytic subunit. (574 aa)
	MTCT_1461	Thiamine pyrophosphate; Belongs to the TPP enzyme family. (522 aa)

Your Current Organism:

Methanothermobacter sp. CaT2

NCBI taxonomy Id: 866790
Other names: M. sp. CaT2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MTCT_1311	MTCT_1312	MTCT_1311	MTCT_1312	Acetolactate synthase regulatory subunit.	Acetolactate synthase catalytic subunit.	0.999
MTCT_1311	MTCT_1461	MTCT_1311	MTCT_1461	Acetolactate synthase regulatory subunit.	Thiamine pyrophosphate; Belongs to the TPP enzyme family.	0.996
MTCT_1311	cimA	MTCT_1311	MTCT_0645	Acetolactate synthase regulatory subunit.	2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.967
MTCT_1311	ilvC	MTCT_1311	MTCT_1310	Acetolactate synthase regulatory subunit.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.999
MTCT_1312	MTCT_1311	MTCT_1312	MTCT_1311	Acetolactate synthase catalytic subunit.	Acetolactate synthase regulatory subunit.	0.999
MTCT_1312	MTCT_1461	MTCT_1312	MTCT_1461	Acetolactate synthase catalytic subunit.	Thiamine pyrophosphate; Belongs to the TPP enzyme family.	0.910
MTCT_1312	cimA	MTCT_1312	MTCT_0645	Acetolactate synthase catalytic subunit.	2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.952
MTCT_1312	ilvC	MTCT_1312	MTCT_1310	Acetolactate synthase catalytic subunit.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.994
MTCT_1461	MTCT_1311	MTCT_1461	MTCT_1311	Thiamine pyrophosphate; Belongs to the TPP enzyme family.	Acetolactate synthase regulatory subunit.	0.996
MTCT_1461	MTCT_1312	MTCT_1461	MTCT_1312	Thiamine pyrophosphate; Belongs to the TPP enzyme family.	Acetolactate synthase catalytic subunit.	0.910
MTCT_1461	cimA	MTCT_1461	MTCT_0645	Thiamine pyrophosphate; Belongs to the TPP enzyme family.	2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.950
MTCT_1461	ilvC	MTCT_1461	MTCT_1310	Thiamine pyrophosphate; Belongs to the TPP enzyme family.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.979
cimA	MTCT_1311	MTCT_0645	MTCT_1311	2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Acetolactate synthase regulatory subunit.	0.967
cimA	MTCT_1312	MTCT_0645	MTCT_1312	2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Acetolactate synthase catalytic subunit.	0.952
cimA	MTCT_1461	MTCT_0645	MTCT_1461	2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Thiamine pyrophosphate; Belongs to the TPP enzyme family.	0.950
cimA	ilvC	MTCT_0645	MTCT_1310	2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.758
ilvC	MTCT_1311	MTCT_1310	MTCT_1311	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Acetolactate synthase regulatory subunit.	0.999
ilvC	MTCT_1312	MTCT_1310	MTCT_1312	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Acetolactate synthase catalytic subunit.	0.994
ilvC	MTCT_1461	MTCT_1310	MTCT_1461	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Thiamine pyrophosphate; Belongs to the TPP enzyme family.	0.979
ilvC	cimA	MTCT_1310	MTCT_0645	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.758