STRINGSTRING
MTCT_0154 MTCT_0154 MTCT_0358 MTCT_0358 MTCT_0551 MTCT_0551 metE metE asd asd MTCT_0718 MTCT_0718 MTCT_0767 MTCT_0767 MTCT_0768 MTCT_0768 MTCT_0881 MTCT_0881 MTCT_1124 MTCT_1124 mat mat ilvE ilvE dadD dadD MTCT_1455 MTCT_1455 MTCT_1495 MTCT_1495 MTCT_1546 MTCT_1546 MTCT_1660 MTCT_1660 MTCT_1710 MTCT_1710 MTCT_1725 MTCT_1725
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTCT_0154Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (325 aa)
MTCT_0358Homoserine dehydrogenase. (337 aa)
MTCT_0551Thiosulfate sulfurtransferase. (286 aa)
metEMethionine synthase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate. (318 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (347 aa)
MTCT_0718Aspartate kinase; Belongs to the aspartokinase family. (406 aa)
MTCT_0767Ferredoxin. (128 aa)
MTCT_0768Conserved hypothetical protein. (514 aa)
MTCT_0881Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (525 aa)
MTCT_1124Homoserine dehydrogenase. (423 aa)
matS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (401 aa)
ilvEAminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (306 aa)
dadDN-ethylammeline chlorohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the [...] (427 aa)
MTCT_1455Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. (280 aa)
MTCT_1495S-adenosyl-L-homocysteine hydrolase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. (417 aa)
MTCT_1546Aspartate aminotransferase. (385 aa)
MTCT_1660Homoserine O-acetyltransferase. (320 aa)
MTCT_1710Translation initiation factor eIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (309 aa)
MTCT_1725Aspartate aminotransferase. (372 aa)
Your Current Organism:
Methanothermobacter sp. CaT2
NCBI taxonomy Id: 866790
Other names: M. sp. CaT2
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