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trpD trpD trpB trpB trpF trpF trpA trpA trpC trpC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (402 aa)
trpFCOGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: gsu:GSU2378 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (208 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa)
trpCCOGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: msi:Msm_1143 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Putative uncharacterized protein; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (262 aa)
Your Current Organism:
Desulfurobacterium thermolithotrophum
NCBI taxonomy Id: 868864
Other names: D. thermolithotrophum DSM 11699, Desulfurobacterium thermolithotrophum BSA, Desulfurobacterium thermolithotrophum DSM 11699, Desulfurobacterium thermolithotrophum str. DSM 11699, Desulfurobacterium thermolithotrophum strain DSM 11699
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