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A0A1A0HEZ3 | Uracil-DNA glycosylase. (280 aa) | ||||
A0A1A0HET4 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (540 aa) | ||||
A0A1A0HER0 | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (1061 aa) | ||||
A0A1A0HEP4 | Prp19-domain-containing protein. (474 aa) | ||||
A0A1A0HEM8 | Uncharacterized protein. (218 aa) | ||||
A0A1A0HEH6 | Myb-like domain-containing protein. (733 aa) | ||||
A0A1A0HEA6 | Uncharacterized protein. (422 aa) | ||||
A0A1A0HDT8 | Uncharacterized protein. (397 aa) | ||||
A0A1A0HDT6 | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (469 aa) | ||||
A0A1A0HDQ0 | SANT domain-containing protein. (610 aa) | ||||
A0A1A0HDK6 | Replication factor C subunit 1. (850 aa) | ||||
A0A1A0HDJ5 | Uncharacterized protein; Belongs to the ATP-dependent DNA ligase family. (972 aa) | ||||
A0A1A0HDD4 | Uncharacterized protein. (1042 aa) | ||||
A0A1A0HDC8 | Uncharacterized protein. (1640 aa) | ||||
A0A1A0HDC7 | Uncharacterized protein. (288 aa) | ||||
A0A1A0HDA8 | P-loop containing nucleoside triphosphate hydrolase protein. (890 aa) | ||||
A0A1A0HDA2 | DNA repair protein. (405 aa) | ||||
A0A1A0HD50 | Uncharacterized protein. (235 aa) | ||||
A0A1A0HD37 | Structural maintenance of chromosomes protein. (1238 aa) | ||||
A0A1A0HCG4 | UV excision repair protein Rad23. (352 aa) | ||||
A0A1A0HCD5 | Putative DNA repair protein Rad4. (693 aa) | ||||
A0A1A0HC60 | Uncharacterized protein. (138 aa) | ||||
A0A1A0HC59 | Fumarase converts fumaric acid to L-malic acid in the TCA cycle. (489 aa) | ||||
A0A1A0HC44 | Rad60-SLD domain-containing protein. (390 aa) | ||||
A0A1A0HC14 | DsRNA-binding domain-like protein. (157 aa) | ||||
A0A1A0HBZ8 | RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (509 aa) | ||||
A0A1A0HBZ4 | Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (780 aa) | ||||
A0A1A0HBX0 | Sister chromatid cohesion protein. (1529 aa) | ||||
A0A1A0HBW3 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
A0A1A0HBR7 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (400 aa) | ||||
A0A1A0HBR2 | P-loop containing nucleoside triphosphate hydrolase protein. (450 aa) | ||||
A0A1A0HBP6 | Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (161 aa) | ||||
A0A1A0HBJ1 | Transcription factor Tfb4. (394 aa) | ||||
A0A1A0HBI8 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3803 aa) | ||||
A0A1A0HBG3 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2382 aa) | ||||
A0A1A0HBB7 | Uncharacterized protein. (238 aa) | ||||
A0A1A0HB48 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (610 aa) | ||||
A0A1A0HB35 | DNA repair protein rad10. (352 aa) | ||||
A0A1A0HAZ2 | DNA_binding_1 domain-containing protein. (119 aa) | ||||
A0A1A0HAV0 | DNA repair helicase rad25. (855 aa) | ||||
A0A1A0HAT2 | P-loop containing nucleoside triphosphate hydrolase protein. (348 aa) | ||||
A0A1A0HAL5 | DNA glycosylase. (378 aa) | ||||
A0A1A0HAK8 | Bromodomain-containing protein. (635 aa) | ||||
A0A1A0HAI9 | AP endonuclease. (337 aa) | ||||
A0A1A0HAF4 | DNA polymerase. (1459 aa) | ||||
A0A1A0HAE1 | Uncharacterized protein. (527 aa) | ||||
A0A1A0HAE0 | SPOC domain-like protein. (703 aa) | ||||
A0A1A0HAD4 | FPG_CAT domain-containing protein. (434 aa) | ||||
A0A1A0HA99 | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (473 aa) | ||||
A0A1A0HA92 | Uncharacterized protein. (864 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (374 aa) | ||||
A0A1A0HA31 | SNF5-domain-containing protein. (948 aa) | ||||
A0A1A0HA23 | NuA4-domain-containing protein. (139 aa) | ||||
A0A1A0HA22 | Uncharacterized protein. (1090 aa) | ||||
A0A1A0HA21 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (233 aa) | ||||
A0A1A0H9Y5 | Uncharacterized protein. (884 aa) | ||||
A0A1A0H9X6 | MRG-domain-containing protein. (332 aa) | ||||
A0A1A0H9W6 | Plus-3-domain-containing protein. (535 aa) | ||||
A0A1A0H9U2 | Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. (808 aa) | ||||
A0A1A0H9T5 | DNA helicase; Belongs to the MCM family. (904 aa) | ||||
A0A1A0H9P1 | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (457 aa) | ||||
A0A1A0H9N4 | Ada_Zn_binding domain-containing protein. (327 aa) | ||||
A0A1A0H9N3 | Uncharacterized protein. (497 aa) | ||||
A0A1A0H9K7 | Uncharacterized protein. (290 aa) | ||||
A0A1A0H9K0 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (195 aa) | ||||
A0A1A0H9E7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (501 aa) | ||||
A0A1A0H9E6 | Cell division control protein; Belongs to the protein kinase superfamily. (310 aa) | ||||
A0A1A0H958 | Uncharacterized protein. (474 aa) | ||||
A0A1A0H8Y2 | DRMBL domain-containing protein. (690 aa) | ||||
A0A1A0H8X1 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (922 aa) | ||||
A0A1A0H8B4 | RNA polymerase II transcription factor B subunit 5. (72 aa) | ||||
A0A1A0H863 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2228 aa) | ||||
A0A1A0H836 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa) | ||||
A0A1A0H817 | DNA_pol_E_B domain-containing protein. (618 aa) | ||||
A0A1A0H7Y1 | Zf-primase domain-containing protein. (505 aa) | ||||
A0A1A0H7X2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (990 aa) | ||||
A0A1A0H7V4 | Replication protein A, subunit RPA32. (258 aa) | ||||
A0A1A0H7P4 | N-acetyltransferase domain-containing protein. (238 aa) | ||||
A0A1A0H7J2 | Uncharacterized protein. (1709 aa) | ||||
A0A1A0H7H1 | Replication factor A protein 3. (106 aa) | ||||
A0A1A0H7D7 | DNA mismatch repair protein MutL. (885 aa) | ||||
A0A1A0H7C0 | ARM repeat-containing protein. (1063 aa) | ||||
A0A1A0H730 | PFU-domain-containing protein. (769 aa) | ||||
A0A1A0H724 | UvrD-like helicase ATP-binding domain-containing protein. (1983 aa) | ||||
A0A1A0H712 | DNA-binding protein. (220 aa) | ||||
A0A1A0H6M2 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (611 aa) | ||||
A0A1A0H6C4 | Uncharacterized protein. (121 aa) | ||||
A0A1A0H6B2 | Uncharacterized protein. (816 aa) | ||||
A0A1A0H674 | Uncharacterized protein. (445 aa) | ||||
A0A1A0H652 | DNA helicase; Belongs to the MCM family. (840 aa) | ||||
A0A1A0H639 | DNA mismatch repair protein MutL. (712 aa) | ||||
A0A1A0H5W5 | PIN domain-like protein. (1043 aa) | ||||
A0A1A0H5U9 | P-loop containing nucleoside triphosphate hydrolase protein. (359 aa) | ||||
A0A1A0H5S5 | Serine/threonine-protein phosphatase. (306 aa) | ||||
A0A1A0H5N4 | Uncharacterized protein. (219 aa) | ||||
A0A1A0H5L4 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (300 aa) | ||||
A0A1A0H5H4 | P-loop containing nucleoside triphosphate hydrolase protein. (327 aa) | ||||
A0A1A0H5C8 | DNA helicase; Belongs to the MCM family. (840 aa) | ||||
A0A1A0H5C1 | ERCC4 domain-containing protein. (539 aa) | ||||
A0A1A0H595 | WD40 repeat-like protein. (1040 aa) | ||||
A0A1A0H525 | P-loop containing nucleoside triphosphate hydrolase protein. (1195 aa) | ||||
A0A1A0H500 | Uncharacterized protein. (1283 aa) | ||||
A0A1A0H4X2 | MRC1 domain-containing protein. (1071 aa) | ||||
A0A1A0H4U0 | Uncharacterized protein. (94 aa) | ||||
A0A1A0H4S0 | Uncharacterized protein. (134 aa) | ||||
A0A1A0H4R8 | UBC-like protein. (137 aa) | ||||
A0A1A0H4R0 | Uncharacterized protein. (916 aa) | ||||
A0A1A0H4P6 | 2OG-FeII_Oxy_2 domain-containing protein. (423 aa) | ||||
A0A1A0H4N2 | Uncharacterized protein. (827 aa) | ||||
A0A1A0H4M7 | DRMBL domain-containing protein. (425 aa) | ||||
A0A1A0H4G8 | Actin/actin-like protein. (376 aa) | ||||
A0A1A0H2A0 | DHS-like NAD/FAD-binding domain-containing protein. (497 aa) | ||||
A0A1A0H270 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1165 aa) | ||||
A0A1A0H261 | CDK-activating kinase assembly factor. (498 aa) | ||||
A0A1A0H260 | PIN domain-like protein. (660 aa) | ||||
A0A1A0H230 | Uncharacterized protein. (163 aa) | ||||
A0A1A0H202 | DNA polymerase. (1067 aa) | ||||
A0A1A0H1X6 | Uncharacterized protein. (1260 aa) | ||||
A0A1A0H1W1 | Uncharacterized protein. (604 aa) | ||||
A0A1A0GZA5 | Uncharacterized protein. (1497 aa) | ||||
A0A1A0GZ20 | Actin/actin-like protein; Belongs to the actin family. (473 aa) | ||||
A0A1A0GYY6 | SPOC domain-like protein. (472 aa) | ||||
A0A1A0HF03 | ATP-dependent DNA helicase. (1033 aa) | ||||
A0A1A0HF05 | DNA ligase. (718 aa) | ||||
A0A1A0HF40 | PNK3P-domain-containing protein. (223 aa) | ||||
A0A1A0HF46 | mRNA export factor Sac3. (1213 aa) | ||||
NTG1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (377 aa) | ||||
A0A1A0HFD1 | SAE2-domain-containing protein. (468 aa) | ||||
A0A1A0HFE6 | Peptidase S59 domain-containing protein. (1401 aa) | ||||
A0A1A0HFF9 | CDT1_C domain-containing protein. (308 aa) | ||||
A0A1A0HFI2 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1132 aa) | ||||
A0A1A0HFL1 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa) | ||||
A0A1A0HFL6 | DNA dependent ATPase. (1113 aa) | ||||
A0A1A0HFM4 | Uncharacterized protein. (691 aa) | ||||
A0A1A0HFM9 | DNA glycosylase. (355 aa) | ||||
A0A1A0HFW4 | Uncharacterized protein. (1048 aa) | ||||
A0A1A0HFY4 | Timeless-domain-containing protein. (1264 aa) | ||||
A0A1A0HG15 | Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (168 aa) | ||||
A0A1A0HG48 | P-loop containing nucleoside triphosphate hydrolase protein. (706 aa) | ||||
A0A1A0HG80 | Uncharacterized protein. (478 aa) | ||||
A0A1A0HG94 | AAA_23 domain-containing protein. (1303 aa) | ||||
A0A1A0HGA2 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase. (188 aa) | ||||
A0A1A0HGC0 | Uncharacterized protein. (1153 aa) | ||||
A0A1A0HGC5 | HMG box domain-containing protein. (89 aa) | ||||
A0A1A0HGD1 | Uncharacterized protein. (182 aa) | ||||
A0A1A0HGS8 | Uncharacterized protein. (2196 aa) | ||||
A0A1A0HGV5 | CDC45-like protein. (692 aa) | ||||
A0A1A0HGW4 | RNI-like protein. (563 aa) | ||||
A0A1A0HGW8 | Chromatin modification-related protein. (262 aa) | ||||
A0A1A0HH80 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (793 aa) | ||||
A0A1A0HHF1 | Uncharacterized protein. (1457 aa) | ||||
A0A1A0HHJ5 | Putative structural maintenance of chromosomes protein. (1080 aa) | ||||
A0A1A0HHK8 | HMG-box. (271 aa) | ||||
A0A1A0HHM0 | DNA repair protein rad18. (419 aa) | ||||
A0A1A0HHM9 | Uncharacterized protein. (1279 aa) | ||||
A0A1A0HHP6 | DNA glycosylase. (275 aa) | ||||
A0A1A0HHQ3 | RMI1_N domain-containing protein. (189 aa) | ||||
A0A1A0HHX9 | Enhancer of polycomb-like protein. (916 aa) | ||||
A0A1A0HI59 | ERCC4 domain-containing protein. (1061 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (780 aa) | ||||
A0A1A0HIA7 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (891 aa) | ||||
A0A1A0HIB4 | SP-RING-type domain-containing protein. (278 aa) | ||||
A0A1A0HIJ5 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (151 aa) | ||||
A0A1A0HIL2 | DNA/RNA polymerase. (750 aa) | ||||
A0A1A0HIR6 | Yeats-domain-containing protein. (220 aa) | ||||
A0A1A0HIS4 | Recombination protein Rad52. (439 aa) | ||||
A0A1A0HIU4 | ERCC4-domain-containing protein. (549 aa) | ||||
A0A1A0HIV6 | Mitochondrial genome maintenance MGM101. (242 aa) | ||||
A0A1A0HIX9 | P-loop containing nucleoside triphosphate hydrolase protein. (807 aa) | ||||
A0A1A0HIY6 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (745 aa) | ||||
A0A1A0HJ01 | DNA helicase; Belongs to the MCM family. (727 aa) | ||||
A0A1A0HJ30 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (344 aa) | ||||
A0A1A0HJ39 | AAA_23 domain-containing protein. (137 aa) | ||||
A0A1A0HJ62 | Nudix hydrolase domain-containing protein. (361 aa) | ||||
A0A1A0HJ86 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2855 aa) | ||||
A0A1A0HJA7 | MAGE domain-containing protein. (292 aa) | ||||
A0A1A0HJG9 | DNA_LIGASE_A3 domain-containing protein. (113 aa) | ||||
A0A1A0HJL2 | Kinase-like protein. (585 aa) | ||||
A0A1A0HJL9 | SPT16-domain-containing protein. (1031 aa) | ||||
A0A1A0HJT8 | Uncharacterized protein. (872 aa) | ||||
A0A1A0HJY1 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (515 aa) | ||||
A0A1A0HK13 | BSD-domain-containing protein. (650 aa) | ||||
A0A1A0HK24 | Helicase C-terminal domain-containing protein. (180 aa) | ||||
A0A1A0HK74 | Kinase-like protein; Belongs to the protein kinase superfamily. (417 aa) | ||||
A0A1A0HK99 | Phospholipase D/nuclease. (613 aa) | ||||
A0A1A0HKA3 | Uncharacterized protein. (442 aa) | ||||
A0A1A0HKC1 | 26S proteasome subunit P45; Belongs to the AAA ATPase family. (440 aa) | ||||
A0A1A0HKD6 | DNA polymerase. (1580 aa) | ||||
A0A1A0HKE2 | Uncharacterized protein. (1156 aa) | ||||
A0A1A0HKG5 | Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (405 aa) | ||||
A0A1A0HKH9 | Structural maintenance of chromosomes protein. (1193 aa) | ||||
A0A1A0HKI5 | DNA helicase; Belongs to the MCM family. (940 aa) | ||||
A0A1A0HKS7 | DNA polymerase alpha binding protein. (881 aa) | ||||
A0A1A0HKX6 | DNA helicase component of transcription factor b. (795 aa) | ||||
A0A1A0HL49 | DNase I-like protein. (560 aa) |