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| | A0A1A0HEV1 | High affinity nicotinic acid plasma membrane permease. (492 aa) |
| | CIA1 | Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (388 aa) |
| | A0A1A0HL19 | GST N-terminal domain-containing protein; Belongs to the GST superfamily. (324 aa) |
| | A0A1A0HKK5 | Cobalamin-independent methionine synthase. (767 aa) |
| | A0A1A0HKJ9 | Glutathione synthetase. (490 aa) |
| | A0A1A0HKB2 | Glutathione degradosome. (970 aa) |
| | A0A1A0HJU6 | HIRA-interacting protein 5. (253 aa) |
| | A0A1A0HJF1 | HSCB_C domain-containing protein. (208 aa) |
| | A0A1A0HJ40 | Cysteine dioxygenase. (246 aa) |
| | A0A1A0HIR1 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (472 aa) |
| | A0A1A0HIP3 | Uncharacterized protein. (576 aa) |
| | A0A1A0HIM1 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (631 aa) |
| | A0A1A0HIJ2 | Uncharacterized protein. (357 aa) |
| | A0A1A0HII6 | Vitamin B6 biosynthesis protein; Belongs to the PdxS/SNZ family. (292 aa) |
| | A0A1A0HI98 | N-terminal nucleophile aminohydrolase. (355 aa) |
| | A0A1A0HHS7 | Gamma-glutamyltranspeptidase. (576 aa) |
| | CFD1 | Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD [...] (294 aa) |
| | TAH18 | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (588 aa) |
| | A0A1A0HHE6 | P-loop containing nucleoside triphosphate hydrolase protein. (316 aa) |
| | A0A1A0HHD4 | Aspartokinase. (534 aa) |
| | A0A1A0HHD1 | Uncharacterized protein. (577 aa) |
| | A0A1A0HHC9 | PLP-dependent transferase. (592 aa) |
| | MET3 | Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. Belongs to the sulfate adenylyltransferase family. (527 aa) |
| | A0A1A0HGW2 | Hydantoinase B multi-domain protein. (1318 aa) |
| | A0A1A0HG86 | Thioesterase/thiol ester dehydrase-isomerase. (341 aa) |
| | A0A1A0HFY0 | Thioesterase/thiol ester dehydrase-isomerase. (341 aa) |
| | A0A1A0HFW2 | Thioesterase/thiol ester dehydrase-isomerase. (334 aa) |
| | NBP35 | Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NB [...] (325 aa) |
| | A0A1A0HFJ1 | Cysteine proteinase 1, mitochondrial; Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. (456 aa) |
| | A0A1A0HFE1 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (493 aa) |
| | A0A1A0HF85 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (514 aa) |
| | A0A1A0HEV9 | Aspartate-semialdehyde dehydrogenase. (366 aa) |
| | A0A1A0HBC3 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (362 aa) |
| | A0A1A0HBK6 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (485 aa) |
| | A0A1A0HBS5 | Uncharacterized protein. (481 aa) |
| | A0A1A0HBT3 | Uncharacterized protein; Belongs to the complex I LYR family. (89 aa) |
| | A0A1A0HBY1 | Zn(2)-C6 fungal-type domain-containing protein. (901 aa) |
| | A0A1A0HBY3 | Rhodanese-like protein. (166 aa) |
| | A0A1A0HC34 | TMP-TENI-domain-containing protein. (510 aa) |
| | A0A1A0HC45 | Flavodoxin-like domain-containing protein. (1421 aa) |
| | A0A1A0HCF4 | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (315 aa) |
| | A0A1A0HCI6 | FeS_assembly_P domain-containing protein. (276 aa) |
| | A0A1A0HCN7 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (324 aa) |
| | A0A1A0HCT6 | Biotin synthase. (375 aa) |
| | A0A1A0HCV1 | Uncharacterized protein. (2214 aa) |
| | UTR4 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (228 aa) |
| | A0A1A0HD02 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (611 aa) |
| | A0A1A0HD23 | HIRA-interacting protein 5. (252 aa) |
| | A0A1A0HD29 | Acetyl-coenzyme A synthetase. (676 aa) |
| | A0A1A0HD31 | Pyridoxal phosphate-dependent enzyme, beta subunit. (388 aa) |
| | A0A1A0HD74 | Cysteine proteinase 1, mitochondrial; Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. (471 aa) |
| | A0A1A0HDM1 | S-adenosyl-L-methionine uroporphyrinogen III transmethylase; Belongs to the precorrin methyltransferase family. (533 aa) |
| | A0A1A0HDY4 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (251 aa) |
| | A0A1A0HE13 | Lipoyl synthase. (259 aa) |
| | A0A1A0HE16 | Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (431 aa) |
| | A0A1A0HE82 | Homoserine O-acetyltransferase. (470 aa) |
| | A0A1A0HE92 | Glutathione S-transferase; Belongs to the GST superfamily. (244 aa) |
| | A0A1A0HED2 | Putative sulfite reductase [NADPH] flavo protein component. (1110 aa) |
| | A0A1A0HEH4 | O-acetylhomoserine ami. (439 aa) |
| | A0A1A0GZ04 | Protein URE2; Plays an important role in the cellular response to the nitrogen source; Belongs to the GST superfamily. (321 aa) |
| | THI4 | Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (332 aa) |
| | A0A1A0H1S6 | Uncharacterized protein; Belongs to the GST superfamily. (249 aa) |
| | A0A1A0H4Y6 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (382 aa) |
| | A0A1A0H543 | 3'5'-bisphosphate nucleotidase. (361 aa) |
| | A0A1A0H5I2 | Glyoxalase I. (326 aa) |
| | A0A1A0H5Q9 | Homocysteine S-methyltransferase. (330 aa) |
| | A0A1A0H5S2 | Adenosylhomocysteinase. (449 aa) |
| | A0A1A0H5Z1 | Dihydrolipoamide succinyltransferase. (420 aa) |
| | A0A1A0H661 | Bola-like protein; Belongs to the BolA/IbaG family. (114 aa) |
| | A0A1A0H696 | Cystathionine beta-l. (403 aa) |
| | A0A1A0H6S9 | Fe-S_biosyn domain-containing protein. (313 aa) |
| | A0A1A0H6Z4 | Uncharacterized protein. (398 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (179 aa) |
| | A0A1A0H7B7 | Phosphoadenosine phosphosulfate reductase. (246 aa) |
| | A0A1A0H7C0 | ARM repeat-containing protein. (1063 aa) |
| | A0A1A0H7C3 | Acetyl-coenzyme A synthetase. (672 aa) |
| | A0A1A0H7M1 | Putative translation initiation factor; Belongs to the eIF-2B alpha/beta/delta subunits family. (375 aa) |
| | A0A1A0H7R3 | Frataxin. (175 aa) |
| | A0A1A0H7S3 | Iron hydrogenase; Belongs to the NARF family. (528 aa) |
| | A0A1A0H7U3 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (447 aa) |
| | A0A1A0H803 | GCS-domain-containing protein. (758 aa) |
| | A0A1A0H809 | Acetyl-CoA synthetase-like protein. (697 aa) |
| | MEU1 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (333 aa) |
| | A0A1A0H8B0 | Uncharacterized protein. (1514 aa) |
| | MDE1 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (250 aa) |
| | A0A1A0H8D8 | TauD-domain-containing protein. (378 aa) |
| | A0A1A0H8R4 | Cysteine desulfurase mitochondrial. (445 aa) |
| | A0A1A0H8Y5 | Uncharacterized protein. (370 aa) |
| | A0A1A0H9M9 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (399 aa) |
| | A0A1A0HA06 | Fe-S_biosyn domain-containing protein. (174 aa) |
| | A0A1A0HA08 | PLP-dependent transferase. (422 aa) |
| | A0A1A0HA41 | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (425 aa) |
| | A0A1A0HAH6 | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (385 aa) |
| | A0A1A0HAP9 | Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (159 aa) |
| | DRE2 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (334 aa) |
| | A0A1A0HB14 | Ferredoxin. (162 aa) |
| | A0A1A0HB33 | Cysteine synthase. (375 aa) |
| | A0A1A0HB85 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (199 aa) |
